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Levodopa
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PSP and Macuna
Hi does Macuna help in PSP related symptoms though lot of articles state that L-DOPA is ineffective for PSP but works for Parkinson's
Hi does Macuna help in PSP related symptoms though lot of articles state that L-DOPA is ineffective for PSP but works for Parkinson's
Seeker_12
in
PSP Association
2 years ago
Acupuncture in "Chapter 26: Traditional Chinese Medicine: a "hidden" wonder behind a different vision".
There have even been studies on the increased efficacy of combining acupuncture with Madopar,
levodopa
with benserazide (Ren 2008, Liu 2017).
There have even been studies on the increased efficacy of combining acupuncture with Madopar,
levodopa
with benserazide (Ren 2008, Liu 2017).
parkinsonshereandnow
in
Cure Parkinson's
2 years ago
Tapering down Levodopa any advice ?
Hi I’m new here and London, UK based. I’m trying to wean off Sinemet (total dose per day 75/300) slowly and completely after taking it for 4 months (since diagnosis). I’ve had more intense non- motor symptoms (e.g. depression exhaustion) trying to come off than before I started the meds. I’m wondering
Hi I’m new here and London, UK based. I’m trying to wean off Sinemet (total dose per day 75/300) slowly and completely after taking it for 4 months (since diagnosis). I’ve had more intense non- motor symptoms (e.g. depression exhaustion) trying to come off than before I started the meds. I’m wondering
Cardiology
in
Cure Parkinson's
2 years ago
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Who wakes up “on”?
Can you please indicate if when you wake up you need a dose of
levodopa
to be able to move, and who feels best first thing before a dose? I just found this picture.
Can you please indicate if when you wake up you need a dose of
levodopa
to be able to move, and who feels best first thing before a dose? I just found this picture.
LAJ12345
in
Cure Parkinson's
2 years ago
CHAPTER 6.THE SEARCH FOR HOPE "OUTSIDE" THE BUBBLE: OTHER NEUROLOGISTS, OTHER MEDICINES, OTHER DISEASES...
the natural internal production (tyrosine-dopa-dopamine) of dopamine instead of supplying it from external sources (
levodopa
-dopamine).
the natural internal production (tyrosine-dopa-dopamine) of dopamine instead of supplying it from external sources (
levodopa
-dopamine).
parkinsonshereandnow
in
Cure Parkinson's
2 years ago
My Current Stack (what is in your stack?)
According to RXlist.com you should NOT take Methylene Blue and Levadopa: https://www.rxlist.com/drug-interactions/methylene-blue-oral-and-
levodopa
-oral-interaction.htm "methylene blue oral and
levodopa
oral methylene blue oral and
levodopa
oral both increase affecting serotonin levels in the blood.
According to RXlist.com you should NOT take Methylene Blue and Levadopa: https://www.rxlist.com/drug-interactions/methylene-blue-oral-and-
levodopa
-oral-interaction.htm "methylene blue oral and
levodopa
oral methylene blue oral and
levodopa
oral both increase affecting serotonin levels in the blood.
Bolt_Upright
in
Cure Parkinson's
2 years ago
Finding some negatives on Berberine (I will keep digging)
EDIT March 17, 2024:
Today somebody shared a link to a two year old post of mine about a report on Berberine being neurotoxic and taking it off of my stack. Within a few months I found other information on Berberine and, using my High School educated brain, decided that Berberine definitely needed
EDIT March 17, 2024:
Today somebody shared a link to a two year old post of mine about a report on Berberine being neurotoxic and taking it off of my stack. Within a few months I found other information on Berberine and, using my High School educated brain, decided that Berberine definitely needed
Bolt_Upright
in
Cure Parkinson's
2 years ago
Man Lost Ability to Walk After Taking Too Many Vitamin B6 Supplements
https://www.insider.com/man-lost-ability-to-walk-too-much-vitamin-b6-supplements-2022-8 more on b6 toxicity https://healthunlocked.com/cure-parkinsons/posts/140776498/the-cause-of-vitamin-b-6-toxicity https://healthunlocked.com/cure-parkinsons/posts/136869228/
levodopa
-medications-vitamin-b6
https://www.insider.com/man-lost-ability-to-walk-too-much-vitamin-b6-supplements-2022-8 more on b6 toxicity https://healthunlocked.com/cure-parkinsons/posts/140776498/the-cause-of-vitamin-b-6-toxicity https://healthunlocked.com/cure-parkinsons/posts/136869228/
levodopa
-medications-vitamin-b6
Hidden
in
Cure Parkinson's
2 years ago
Phosphodiesterase 9 inhibition prolongs the antiparkinsonian action of l-DOPA in parkinsonian non-human primates
https://pubmed.ncbi.nlm.nih.gov/35461880/ These results indicate that cGMP upregulation interacts with dopamine signaling to enhance the l-DOPA reversal of parkinsonian motor disability. Therefore, striatal PDE9 inhibition may be further explored as a strategy to improve motor responses to l-DOPA in
https://pubmed.ncbi.nlm.nih.gov/35461880/ These results indicate that cGMP upregulation interacts with dopamine signaling to enhance the l-DOPA reversal of parkinsonian motor disability. Therefore, striatal PDE9 inhibition may be further explored as a strategy to improve motor responses to l-DOPA in
Hidden
in
Cure Parkinson's
2 years ago
My Liver on Kratom....
I was on DAs (carbidopa-
levodopa
, pramipexole) for about 35 years until finally augmenting on prami about a year ago (2021). I've spent countless hours researching over the years and have tried every diet, supplement, or treatment that you can think of.
I was on DAs (carbidopa-
levodopa
, pramipexole) for about 35 years until finally augmenting on prami about a year ago (2021). I've spent countless hours researching over the years and have tried every diet, supplement, or treatment that you can think of.
flobbest
in
Restless Legs Syndrome
1 year ago
Encouraging Stem Cell Trial Results
The % OFF-Time, which is the time during the day when
levodopa
medication is not performing optimally and PD symptoms return, decreased an average 47% from the baseline at 12 months post transplantation in cohort 2.
The % OFF-Time, which is the time during the day when
levodopa
medication is not performing optimally and PD symptoms return, decreased an average 47% from the baseline at 12 months post transplantation in cohort 2.
jimcaster
in
Cure Parkinson's
2 years ago
Sudden loss of ability to move?
He's been labeled "Possible CBD" because he didn't respond to
levodopa
like a normal Parkinson's patient. But does this sound more like PSP? Thanks in advance for any pointers!
He's been labeled "Possible CBD" because he didn't respond to
levodopa
like a normal Parkinson's patient. But does this sound more like PSP? Thanks in advance for any pointers!
LostinHeadSpace
in
PSP Association
2 years ago
Carbadopa/Levadopa
I am currently taking 1 pill three times a day of Carbidopa
levodopa
. I'm experiencing some dyskinesia. How do I cut back on the
levodopa
-carbidopa to eliminate the dyskinesia? Thanks for your help
I am currently taking 1 pill three times a day of Carbidopa
levodopa
. I'm experiencing some dyskinesia. How do I cut back on the
levodopa
-carbidopa to eliminate the dyskinesia? Thanks for your help
Smittybear7
in
Cure Parkinson's
2 years ago
Any advice about weaning off of levodopa and starting amantadine.
I have developed dyskinesia and doctors tried reducing
levodopa
thinking I was getting too much but dyskinesia persisted.
I have developed dyskinesia and doctors tried reducing
levodopa
thinking I was getting too much but dyskinesia persisted.
Hidden
in
Cure Parkinson's
2 years ago
How do you deal with central pain syndrome?
It sometimes runs from my brain to the bottom of my foot running on a straight line through my weak side reaching even my genitals (i know this is intimate but i think is relevant) it feels like an all body tooth sensitivity and yes
levodopa
seems to dull it a bit but the moment im off the pain is there
It sometimes runs from my brain to the bottom of my foot running on a straight line through my weak side reaching even my genitals (i know this is intimate but i think is relevant) it feels like an all body tooth sensitivity and yes
levodopa
seems to dull it a bit but the moment im off the pain is there
HekateMoon
in
Cure Parkinson's
2 years ago
Dhivy, New Levodopa Pill new, easy-to-break levodopa/carbidopa tablet approved by FDA
A tablet of Dhivy includes 100 mg
levodopa
and 25 mg carbidopa. (These are the same amounts as in other immediate-release
levodopa
/carbidopa tablets, such as Sinemet.) A quarter tablet of Dhivy contains 25 mg
levodopa
and 6.25 mg carbidopa.
A tablet of Dhivy includes 100 mg
levodopa
and 25 mg carbidopa. (These are the same amounts as in other immediate-release
levodopa
/carbidopa tablets, such as Sinemet.) A quarter tablet of Dhivy contains 25 mg
levodopa
and 6.25 mg carbidopa.
Hidden
in
Cure Parkinson's
2 years ago
Discovery of levodopa-induced dyskinesia-associated genes using genomic studies in patients and Drosophila behavioral analyses
Similar to the therapeutic effect of Ldopa in patients, acute Ldopa treatment restore the motor defect of Parkinsons flies, while prolonged treatments cause LID-related symptoms, such as increased yawing, freezing & abrupt acceleration of locomotives
Similar to the therapeutic effect of Ldopa in patients, acute Ldopa treatment restore the motor defect of Parkinsons flies, while prolonged treatments cause LID-related symptoms, such as increased yawing, freezing & abrupt acceleration of locomotives
Farooqji
in
Cure Parkinson's
2 years ago
Q10 1200mg for PSP?
My mother in law was diagnosed PSP 1 year ago and she is not responsive to
Levodopa
med. Dr. says only option is management. I read about Q10 1200 mg recommended for PSP as adjunct treatment. Does anyone have experience with Q10? Her doctor said she has no experience with Q10.
My mother in law was diagnosed PSP 1 year ago and she is not responsive to
Levodopa
med. Dr. says only option is management. I read about Q10 1200 mg recommended for PSP as adjunct treatment. Does anyone have experience with Q10? Her doctor said she has no experience with Q10.
DaniSS
in
PSP Association
2 years ago
Jelly loaded "nano gel" with mucuna
Jelly loaded "nano gel" with mucuna? "Natural L-dopa, M. pruriens seed extract and prepared a nanogel containing extract incorporated into a jelly formulation for use as a "functional food" in elderly Parkinson's disease. Maybe for other PD meds too? https://twitter.com/MichaelOkun/status/1531274710591451138
Jelly loaded "nano gel" with mucuna? "Natural L-dopa, M. pruriens seed extract and prepared a nanogel containing extract incorporated into a jelly formulation for use as a "functional food" in elderly Parkinson's disease. Maybe for other PD meds too? https://twitter.com/MichaelOkun/status/1531274710591451138
Hidden
in
Cure Parkinson's
2 years ago
Road block
Levodopa
has stopped working after only 3 months, I was only allowed minimum dose, so the much hated jerking has returned, plus the weird walking. No suggestion how to improve slow speech or loss of fine motor skills.
Levodopa
has stopped working after only 3 months, I was only allowed minimum dose, so the much hated jerking has returned, plus the weird walking. No suggestion how to improve slow speech or loss of fine motor skills.
MONIREN
in
Functional Neurological Disorder - FND Hope
2 years ago
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