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Recent paper on osteonecrosis of the jaw - some extracts relevant for PCa patients are given below
The main side effect of bisphosphonates is osteonecrosis of the jaw, but other side effects can also occur, such as gastrointestinal disturbances, atypical femur
fractures
, inflammation of the esophagus with mucosal erosions, secondary hyperparathyroidism, atrial fibrillation, eye discharge, muscle pain
The main side effect of bisphosphonates is osteonecrosis of the jaw, but other side effects can also occur, such as gastrointestinal disturbances, atypical femur
fractures
, inflammation of the esophagus with mucosal erosions, secondary hyperparathyroidism, atrial fibrillation, eye discharge, muscle pain
Graham49
in
Advanced Prostate Cancer
1 year ago
Osteonecrosis and Xgeva
Been a while since last post. I have been on the Xgeva 3 month shot since June 2019. Just been diagnosed with TMJ and my last shot was Mar 2022. How long will it take for Xgeva to leave the system since TMJ still feels like it is progressing? My oral surgeon does not want to operate unless a piece
Been a while since last post. I have been on the Xgeva 3 month shot since June 2019. Just been diagnosed with TMJ and my last shot was Mar 2022. How long will it take for Xgeva to leave the system since TMJ still feels like it is progressing? My oral surgeon does not want to operate unless a piece
ctflatlander
in
Advanced Prostate Cancer
2 years ago
Denosumab if bone strength increasing on ADT?
Hi everyone, my father was diagnosed with Stage 4 PCa last year (multiple bone mets). He has responded well to ADT so far with PSA dropping from 500 to 0.65 in 14 months and corresponding decrease in PSMA avidity seen in scans. At the time of his diagnosis he was advised Denosumab because a Dexa scan
Hi everyone, my father was diagnosed with Stage 4 PCa last year (multiple bone mets). He has responded well to ADT so far with PSA dropping from 500 to 0.65 in 14 months and corresponding decrease in PSMA avidity seen in scans. At the time of his diagnosis he was advised Denosumab because a Dexa scan
Rodeoz15
in
Advanced Prostate Cancer
2 years ago
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Feeling Accomplished
I completed the Couch to 5K program on 28 June and it has given me a feeling of real self accomplishment as well as having become more active and healthier than I have in a long time. I live in Gran Canaria but completed weeks 4 to 9 whist visiting back in the UK, so I benefited from the cooler temperatures
I completed the Couch to 5K program on 28 June and it has given me a feeling of real self accomplishment as well as having become more active and healthier than I have in a long time. I live in Gran Canaria but completed weeks 4 to 9 whist visiting back in the UK, so I benefited from the cooler temperatures
PDIGC
Graduate
in
Couch to 5K
2 years ago
NSAIDS anyone ?
Shortly afterwards he rang to say that the latest X-ray had shown 3 repairing pelvic
fractures
, one of which was a stress fracture , and asked if I had fallen . I hadn’t , and I asked if these could be
fractures
caused by my fall the previous May when I had hurt my hip .
Shortly afterwards he rang to say that the latest X-ray had shown 3 repairing pelvic
fractures
, one of which was a stress fracture , and asked if I had fallen . I hadn’t , and I asked if these could be
fractures
caused by my fall the previous May when I had hurt my hip .
Briefencounter
in
NRAS
2 years ago
Methotrexate in the US
Since our Supreme Court has removed Roe v Wade allowing abortion something has happened that most did not expect. Women of reproctive age are being denied their methotrexate that they've been taking for years as a treatment for things like RA because it is also a drug used in abortions. I know that most
Since our Supreme Court has removed Roe v Wade allowing abortion something has happened that most did not expect. Women of reproctive age are being denied their methotrexate that they've been taking for years as a treatment for things like RA because it is also a drug used in abortions. I know that most
Amkoffee
in
PMRGCAuk
2 years ago
Scan resuts etc.
After making me wait a week I finally got the results of a CT scan and bone scan. I think I mentioned that I had had a monor accident (falling about a foot into a shelf at chest height) and had really horrible pain that would not go away. Went to ER and the ER doctor interpreted the CT scan as metastatic
After making me wait a week I finally got the results of a CT scan and bone scan. I think I mentioned that I had had a monor accident (falling about a foot into a shelf at chest height) and had really horrible pain that would not go away. Went to ER and the ER doctor interpreted the CT scan as metastatic
spencoid2
in
Advanced Prostate Cancer
2 years ago
Modified Citrus Pectin Treatment in Non-Metastatic Biochemically Relapsed Prostate Cancer: Results of a Phase II Study
Modified Citrus Pectin https://www.nutraceuticalbusinessreview.com/news/article_page/The_groundbreaking_momentum_of_modified_citrus_pectin_research/1567 https://www.mdpi.com/2072-6643/13/12/4295
Modified Citrus Pectin https://www.nutraceuticalbusinessreview.com/news/article_page/The_groundbreaking_momentum_of_modified_citrus_pectin_research/1567 https://www.mdpi.com/2072-6643/13/12/4295
Bigm789
in
Advanced Prostate Cancer
2 years ago
Tough Questions
His PSA jumps about 30 points ever week or two (it is at 90 now), bone Mets from head to toe, his pelvis is solid Mets and he has three
fractures
in his spine, he can barely walk, has extreme fatigue and extreme pain, and is not the same person from two weeks ago, let alone one year ago.
His PSA jumps about 30 points ever week or two (it is at 90 now), bone Mets from head to toe, his pelvis is solid Mets and he has three
fractures
in his spine, he can barely walk, has extreme fatigue and extreme pain, and is not the same person from two weeks ago, let alone one year ago.
Sipj
in
Advanced Prostate Cancer
2 years ago
Provia
But in the same breath talking about
fractures
, thigh bones problems, dental issues. Can you give me some advice can you share with me any stories that you might have about this particular drug? Thank you so much.
But in the same breath talking about
fractures
, thigh bones problems, dental issues. Can you give me some advice can you share with me any stories that you might have about this particular drug? Thank you so much.
Whitelite
in
Osteoporosis Support
2 years ago
Understanding Osteoporosis
You may hear or read these described as fragility
fractures
.
Newly diagnosed?
You may hear or read these described as fragility
fractures
.
Newly diagnosed?
ROSModerator
Partner
in
Bone Health and Osteoporosis UK
2 years ago
Why men with prostate cancer should care about the Supreme Court abortion decision
I remember a patient who was fired from his job when his employer found out he had prostate cancer. Life insurance can still be denied if you release medical history info. But neither employers nor life insurance have any recourse if you do not allow them to have that info. What protects you is the
I remember a patient who was fired from his job when his employer found out he had prostate cancer. Life insurance can still be denied if you release medical history info. But neither employers nor life insurance have any recourse if you do not allow them to have that info. What protects you is the
Tall_Allen
in
Advanced Prostate Cancer
2 years ago
Soy Isoflavones-Updated 071522
Hi Guys, I wanted to share my experience with taking soy isoflavones. I read here about some studies that showed a possible benefit in taking soy. So I ordered some from Life Extension supplement company. I thought why not give it a shot. So I start taking them on 03/19. The recommended dose is
Hi Guys, I wanted to share my experience with taking soy isoflavones. I read here about some studies that showed a possible benefit in taking soy. So I ordered some from Life Extension supplement company. I thought why not give it a shot. So I start taking them on 03/19. The recommended dose is
pbaldwin
in
Advanced Prostate Cancer
2 years ago
Loosing muscles
During last 8 years on ADT, and last 2 years of Xtandi, I am facing continious loosing muscles, as well as weight, of course. Bones metastases prevent me regular training, exept walking dogs few times daily. Any contribution of the way of gaining muscles, or just stoping melting them further, would
During last 8 years on ADT, and last 2 years of Xtandi, I am facing continious loosing muscles, as well as weight, of course. Bones metastases prevent me regular training, exept walking dogs few times daily. Any contribution of the way of gaining muscles, or just stoping melting them further, would
beogradjanin
in
Advanced Prostate Cancer
2 years ago
Switching from Firmagon to Lucrin or Eligard
Hi, this is ALEX from Malaysia. First Dx 2016 psa 8.34, gs 3+4. Had RP 10/2017 with positive margin. Did salvage IMRT 8/4/2019 at psa 2.43 without adt. After 2nd Bcr post Salvage RT, psa rose from 0.05 to 0.94 , I started on FIRMAGON on 8/ 3/ 2022. ( Throughout this 5 1/2 year journey, a total of 4
Hi, this is ALEX from Malaysia. First Dx 2016 psa 8.34, gs 3+4. Had RP 10/2017 with positive margin. Did salvage IMRT 8/4/2019 at psa 2.43 without adt. After 2nd Bcr post Salvage RT, psa rose from 0.05 to 0.94 , I started on FIRMAGON on 8/ 3/ 2022. ( Throughout this 5 1/2 year journey, a total of 4
huraymond
in
Advanced Prostate Cancer
2 years ago
Post radiotherapy back pain
The medical experts put this down to the micro
fractures
caused by the radiation treatment. However, they do not seem to be able to advise on the area of visible bruising I also get at my low back which comes and goes at the same time as the pain.
The medical experts put this down to the micro
fractures
caused by the radiation treatment. However, they do not seem to be able to advise on the area of visible bruising I also get at my low back which comes and goes at the same time as the pain.
Wolfs131
in
Pelvic Radiation Disease Association
2 years ago
Calcium lactate
Hello everyone please can you help me with answer I start to take calcium lactate in powder form , because of my knee pains , and I’m in menopause. Any suggestions thank you 🙏
Hello everyone please can you help me with answer I start to take calcium lactate in powder form , because of my knee pains , and I’m in menopause. Any suggestions thank you 🙏
Charly1999
in
Thyroid UK
2 years ago
i have many conditions dont know where to start ,
times and 5 weeks ago was in the kitchin felt a severe pain in my back and down i went was taken to hospital whee i was x rayed no fracture i was told was sent home in severe pain 5 days later got a phone call prom my doctor my discharge notes from the hospital were sent to her stating i have 3 wedge
fractures
times and 5 weeks ago was in the kitchin felt a severe pain in my back and down i went was taken to hospital whee i was x rayed no fracture i was told was sent home in severe pain 5 days later got a phone call prom my doctor my discharge notes from the hospital were sent to her stating i have 3 wedge
fractures
sammason57
in
Bone Health and Osteoporosis UK
2 years ago
PDE5 inhibitors eg Taladalfal etc. 2 papers, one a cohort study showing positive survival association. The second about invitro studies
The association of phosphodiesterase-5 inhibitors with the biochemical recurrence-free and overall survival of patients with prostate cancer following radical prostatectomy
Author links open overlay panelKelsey T.DanleyM.D.aAlanTanM.D.bWilliam J.CatalonaM.D.cRobinLeikinPh.D.dIreneHelenowskiPh.D.eBorkoJovanovicPh.D.eMichaelGurleyB.A.dTimothy
The association of phosphodiesterase-5 inhibitors with the biochemical recurrence-free and overall survival of patients with prostate cancer following radical prostatectomy
Author links open overlay panelKelsey T.DanleyM.D.aAlanTanM.D.bWilliam J.CatalonaM.D.cRobinLeikinPh.D.dIreneHelenowskiPh.D.eBorkoJovanovicPh.D.eMichaelGurleyB.A.dTimothy
Graham49
in
Advanced Prostate Cancer
2 years ago
staying in a hotel with asthma: first intl trip in 2020
Hi all, Just wanted to report on my first attempt for international travel in 2+ years (since the pandemic and then since my asthma exacerbation). I've been on Xolair for the last 7 months, and gradually built the confidence to drive across the channel to attend a wedding. I had a FFP2 mask on while
Hi all, Just wanted to report on my first attempt for international travel in 2+ years (since the pandemic and then since my asthma exacerbation). I've been on Xolair for the last 7 months, and gradually built the confidence to drive across the channel to attend a wedding. I had a FFP2 mask on while
runcyclexcski
in
Asthma Community Forum
2 years ago
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