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Estradiol / Dienogest
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Estrogen Receptors
New study below [1]. At the time I was diagnosed (2004), there was enough research on the 'new' estrogen receptor [ERbeta], to cause concern. At diagnosis, ERbeta has generally become downregulated. In contrast, ERalpha, which is otherwise restricted to stromal cells, starts to appear in PCa (epithelial
New study below [1]. At the time I was diagnosed (2004), there was enough research on the 'new' estrogen receptor [ERbeta], to cause concern. At diagnosis, ERbeta has generally become downregulated. In contrast, ERalpha, which is otherwise restricted to stromal cells, starts to appear in PCa (epithelial
pjoshea13
in
Fight Prostate Cancer
1 year ago
Dienogest and the coil
Hi everyone, My doctor prescribed me Dienogest for endo pain and said it was fine to take it even though I have a mirena coil. However, in the leaflet it says not to take it if you have a coil… does anyone have any idea? I ask because my moods have been all over the place and I wonder if it’s because
Hi everyone, My doctor prescribed me Dienogest for endo pain and said it was fine to take it even though I have a mirena coil. However, in the leaflet it says not to take it if you have a coil… does anyone have any idea? I ask because my moods have been all over the place and I wonder if it’s because
Badger17
in
Endometriosis UK
1 year ago
day 12 lining scan - need advice
hi all, I had my day 12 endometrial lining thickness scan and it’s only on 5.96mm. I’ve been on estradiol since day 1. Sonography let said it’s less than where it should be and my clinic in Spain will reply tomorrow but I’m obviously stressing out now! You’re welcome your thoughts on it. Thanks in
hi all, I had my day 12 endometrial lining thickness scan and it’s only on 5.96mm. I’ve been on estradiol since day 1. Sonography let said it’s less than where it should be and my clinic in Spain will reply tomorrow but I’m obviously stressing out now! You’re welcome your thoughts on it. Thanks in
IVFat43
in
Fertility Network UK
1 year ago
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Can menopause trigger hypothyroidism?
When I turned 50 (few years ago now) over a few months my health changed, I developed weakness, brain fog, insomnia, heat intolerance, poor appetite, joint aches, atrophy etc etc. I even stopped exercising when I had been reasonably fit before. GP sent off some bloods and called me within days to start
When I turned 50 (few years ago now) over a few months my health changed, I developed weakness, brain fog, insomnia, heat intolerance, poor appetite, joint aches, atrophy etc etc. I even stopped exercising when I had been reasonably fit before. GP sent off some bloods and called me within days to start
M33R4
in
Menopause and Perimenopause Support
1 year ago
Thin womb lining at D8 scan
Hi All, I haven’t posted on here for a little while as my last cycle was cancelled. I didn’t respond well to the stims 😔 Trying again this month but although I have 3 follicles on D8 (I have low AMH so I don’t respond well anyway), now my womb lining is too thin at 5.4mm. I’m taking aspirin and dr is
Hi All, I haven’t posted on here for a little while as my last cycle was cancelled. I didn’t respond well to the stims 😔 Trying again this month but although I have 3 follicles on D8 (I have low AMH so I don’t respond well anyway), now my womb lining is too thin at 5.4mm. I’m taking aspirin and dr is
Cica22
in
Fertility Network UK
1 year ago
dienogest!? Advice needed please xx
I had an appointment today with my endo consultant, he’s suggested I start taking Dienogest,he said it’s relatively new in the UK but medical data suggests to can work. Have any of you tried it? From what I can see online there’s mixed reviews so I’m not sure what to do for the best.
I had an appointment today with my endo consultant, he’s suggested I start taking Dienogest,he said it’s relatively new in the UK but medical data suggests to can work. Have any of you tried it? From what I can see online there’s mixed reviews so I’m not sure what to do for the best.
Laulou87
in
Endometriosis UK
2 years ago
Help understanding blood tests. Undermedicated or perimenopausal?
help understanding latest blood tests...on only 37mg of levothryoxine and symtoms worse than ever but blood tests (TSH) say am on too much. Has anyone had this? Consultant has said maybe I am also going through perimenopause (have just turned 40). latest bloods show: TSH 0.01 mI (L 0.27 - 4.20mIU
help understanding latest blood tests...on only 37mg of levothryoxine and symtoms worse than ever but blood tests (TSH) say am on too much. Has anyone had this? Consultant has said maybe I am also going through perimenopause (have just turned 40). latest bloods show: TSH 0.01 mI (L 0.27 - 4.20mIU
Frankyn
in
Thyroid UK
1 year ago
Fluctuating AMH Levels and then huge decline in one year.
Hi, I am just interested in whether anyone has been in a similar position. I am 34. I had my AMH and AFC tested 3 months before I turned 34. My AFC was good at 19 but my AMH was low for my age at 8.9. Two weeks later, I got my AMH retested and it was 6.2. I thought AMH wasn’t meant to change that much
Hi, I am just interested in whether anyone has been in a similar position. I am 34. I had my AMH and AFC tested 3 months before I turned 34. My AFC was good at 19 but my AMH was low for my age at 8.9. Two weeks later, I got my AMH retested and it was 6.2. I thought AMH wasn’t meant to change that much
48JJ
in
Fertility Network UK
1 year ago
Estradiol patches for FET coming off
Any advice welcome…I am on estradiol patches 2 x weekly for my FET. The patches are secure but are coming loose before the 3.5 days is up. My current patch has only been on 2 days and has mainly come off, I have tried to secure it back down with micropore tape but not sure what to do. Worried I f I
Any advice welcome…I am on estradiol patches 2 x weekly for my FET. The patches are secure but are coming loose before the 3.5 days is up. My current patch has only been on 2 days and has mainly come off, I have tried to secure it back down with micropore tape but not sure what to do. Worried I f I
Cricril
in
Fertility Network UK
1 year ago
Vertebral Fractures [VF]
New study from the Netherlands, below [1]. One would expect bone issues with ADT, since near-zero testosterone equates to near-zero estradiol. When estradiol goes below 12 pg/mL (my limit, based on old non-PCa studies), bone loss can be rapid. But this study looked at men who were about to start ADT
New study from the Netherlands, below [1]. One would expect bone issues with ADT, since near-zero testosterone equates to near-zero estradiol. When estradiol goes below 12 pg/mL (my limit, based on old non-PCa studies), bone loss can be rapid. But this study looked at men who were about to start ADT
pca2004
in
Fight Prostate Cancer
1 year ago
Experiences of Dienogest/Zalkya?
Currently taking the mini pill which I started around 4 months ago, but unfortunately I am still in quite a lot of pain on a daily basis. My specialist has suggested dienogest for my next line of treatment but I am absolutely terrified of the side effects I have read on the internet. I can deal with
Currently taking the mini pill which I started around 4 months ago, but unfortunately I am still in quite a lot of pain on a daily basis. My specialist has suggested dienogest for my next line of treatment but I am absolutely terrified of the side effects I have read on the internet. I can deal with
puzzleprincess
in
Endometriosis UK
2 years ago
anything different to do after another failed fet?
hi all, this is my first post here. Sadly I received the news that my 3rd fet cycle failed today. My clinic has changed the protocol of each cycle with this one being more intense I.e. short down regulation (about 2 weeks) with buserline for mild ademiosis, lubion + pessaries for progestrone, patches
hi all, this is my first post here. Sadly I received the news that my 3rd fet cycle failed today. My clinic has changed the protocol of each cycle with this one being more intense I.e. short down regulation (about 2 weeks) with buserline for mild ademiosis, lubion + pessaries for progestrone, patches
Bed12
in
Fertility Network UK
1 year ago
Anxious - Endo and bowel surgery
Hello all! Joined this group when I discovered I had endometriosis. I’ve since had a laparoscopy which has confirmed severe endo, obliterated pouch of Douglas, adhesions to the bowel. MRI has also confirmed adenomyosis. Not great! I’ve tried dienogest which just turned me into a psycho so not keen
Hello all! Joined this group when I discovered I had endometriosis. I’ve since had a laparoscopy which has confirmed severe endo, obliterated pouch of Douglas, adhesions to the bowel. MRI has also confirmed adenomyosis. Not great! I’ve tried dienogest which just turned me into a psycho so not keen
Highlandgoat
in
Endometriosis UK
2 years ago
Hormone Results from medichecks
Hi and thank you for a your help. I just wonder if it might shed some light on how i am feeling alongside the hypo issues if i show the Hormone results, as they don't make any sense to me. FSH 104.27 IU/L Ref Range for Post - Meno 16.71 -113.59 LH 30.6 IU/L Ref Range
Hi and thank you for a your help. I just wonder if it might shed some light on how i am feeling alongside the hypo issues if i show the Hormone results, as they don't make any sense to me. FSH 104.27 IU/L Ref Range for Post - Meno 16.71 -113.59 LH 30.6 IU/L Ref Range
mary18
in
Thyroid UK
2 years ago
Can/does NDT elevate slightly oestradiol and progesterone in menopaused women?
I have not found any info on this. Every best wish, G.
I have not found any info on this. Every best wish, G.
Gillybean1
in
Thyroid UK
2 years ago
Timing of meds and supplements?
I wonder if anyone is able to share their optimal timing schedule- I feel like there aren’t enough hours in the day for all the different tablets with their exclusion zones! Not to mention fitting coffee into the day! This is what I currently take:
On waking:
ferograd C iron (every other day
I wonder if anyone is able to share their optimal timing schedule- I feel like there aren’t enough hours in the day for all the different tablets with their exclusion zones! Not to mention fitting coffee into the day! This is what I currently take:
On waking:
ferograd C iron (every other day
musette
in
Thyroid UK
2 years ago
burning from estradiol vag cream
I've been prescribed a generic estradiol vaginal cream for vaginal atrophy due to menopause. I'm actually still in perimenopause but about 4 years ago (age 46) I began to get UTI's after intercourse and would feel irritated and itchy also. It's just gotten worse over time and now it's really bad.
I've been prescribed a generic estradiol vaginal cream for vaginal atrophy due to menopause. I'm actually still in perimenopause but about 4 years ago (age 46) I began to get UTI's after intercourse and would feel irritated and itchy also. It's just gotten worse over time and now it's really bad.
sungirl55
in
Menopause and Perimenopause Support
2 years ago
Should I be worried?
Hello my brothers and sisters. After 3 years of ADT (Zoladex) and with a stable PSA of .13, my MO put me on vacation (to my great joy) I June, 2022. It has now been 5 months. Three months into my vacatión I could begin to feel the changes with greater strength, muscle mass and hope, although the hot
Hello my brothers and sisters. After 3 years of ADT (Zoladex) and with a stable PSA of .13, my MO put me on vacation (to my great joy) I June, 2022. It has now been 5 months. Three months into my vacatión I could begin to feel the changes with greater strength, muscle mass and hope, although the hot
CountryJoe
in
Advanced Prostate Cancer
2 years ago
[b]Diabetes and the Prostate: Elevated Fasting Glucose, Insulin Resistance and Higher Levels of Adrenal Steroids in Prostate Cancer[/b]
This post is prompted by a new German study: "
Diabetes and the Prostate: Elevated Fasting Glucose, Insulin Resistance and Higher Levels of Adrenal Steroids in Prostate Cancer
" [1] [It has been 20 years since a nodule was detected on my prostate. I have been spending the past few months of self-exile
This post is prompted by a new German study: "
Diabetes and the Prostate: Elevated Fasting Glucose, Insulin Resistance and Higher Levels of Adrenal Steroids in Prostate Cancer
" [1] [It has been 20 years since a nodule was detected on my prostate. I have been spending the past few months of self-exile
pjoshea13
in
Fight Prostate Cancer
2 years ago
Endo and mega high levels of oestradiol...
My cognitive issues/brain fog/inability to learn new info/feeling confused and forgetful; they are getting worse and worse. I thought these would be menopausal but my blood tests today show that I am not menopausal at all. How can this be? My oestradiol levels are 1888 pmol/L and FSH is 6.8iu/L and LH
My cognitive issues/brain fog/inability to learn new info/feeling confused and forgetful; they are getting worse and worse. I thought these would be menopausal but my blood tests today show that I am not menopausal at all. How can this be? My oestradiol levels are 1888 pmol/L and FSH is 6.8iu/L and LH
CofG
in
Endometriosis UK
2 years ago
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