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Enzalutamide
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Xtandi.....(enzalutamide tablets)
I have received my medication, and it is Xtandi, not Erleada which I thought it would be from the brochure I received from the physician.....Anyone using this stuff.....and if you will.....what's the "scoop" on this stuff..........thanks......I will start this in early May
I have received my medication, and it is Xtandi, not Erleada which I thought it would be from the brochure I received from the physician.....Anyone using this stuff.....and if you will.....what's the "scoop" on this stuff..........thanks......I will start this in early May
eddieboy52
in
Advanced Prostate Cancer
1 year ago
Xtandi (enzalutamide) +ADT slows metastases in recurrent men
https://www.prostatecancer.news/2023/05/xtandi-
enzalutamide
-adt-slows.html Early treatment with either may allow extended ADT vacations.
https://www.prostatecancer.news/2023/05/xtandi-
enzalutamide
-adt-slows.html Early treatment with either may allow extended ADT vacations.
Tall_Allen
in
Advanced Prostate Cancer
1 year ago
Hello, good People!
Now He starter
enzalutamide
. Every month he has an Xgeva, for bones. He feels fine, he s ok.I just want to ask you, should we be scared? I m very affraid of what I read about life expectancy, about pronostics.
Now He starter
enzalutamide
. Every month he has an Xgeva, for bones. He feels fine, he s ok.I just want to ask you, should we be scared? I m very affraid of what I read about life expectancy, about pronostics.
tuta1960
in
Advanced Prostate Cancer
1 year ago
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Elreada: minimal effective dose
Before Elreada came along I was thinking, if forced, that I would opt for
Enzalutamide
but prefering to go with a shot at a minimal effectiv dose of half or a quarter as some have recorded here and elsewhere. Now I am thinking that I might go for Elreada.
Before Elreada came along I was thinking, if forced, that I would opt for
Enzalutamide
but prefering to go with a shot at a minimal effectiv dose of half or a quarter as some have recorded here and elsewhere. Now I am thinking that I might go for Elreada.
Rickytarr
in
Fight Prostate Cancer
1 year ago
FYI: New data on progression of visceral mets without PSA progression (discordance) and ARAT/docetaxel therapy
., abiraterone and
enzalutamide
) may be susceptible to discordant progression. With the incorporation of early ARAT in SOC, we may see this number rise.
., abiraterone and
enzalutamide
) may be susceptible to discordant progression. With the incorporation of early ARAT in SOC, we may see this number rise.
SeosamhM
in
Advanced Prostate Cancer
10 months ago
No relief for Xtandi Prices
Health and Human Services (HHS) Secretary Xavier Becerra to grant march-in rights—under which the government can grant patent licenses to companies other than a drug's manufacturer—for
enzalutamide
, which is sold under the brand name Xtandi by Pfizer and Japanese pharmaceutical giant Astellas.
Health and Human Services (HHS) Secretary Xavier Becerra to grant march-in rights—under which the government can grant patent licenses to companies other than a drug's manufacturer—for
enzalutamide
, which is sold under the brand name Xtandi by Pfizer and Japanese pharmaceutical giant Astellas.
Magnus1964
in
Advanced Prostate Cancer
1 year ago
Retrospective study shows enzalutamide gives slightly longer survival than abiraterone for mCRCP
After propensity score matching by age and cardiac comorbidities,
enzalutamide
was significantly associated with a 10% decreased mortality risk compared with abiraterone.
After propensity score matching by age and cardiac comorbidities,
enzalutamide
was significantly associated with a 10% decreased mortality risk compared with abiraterone.
Graham49
in
Advanced Prostate Cancer
2 years ago
PSA still rising after 9 cycles of Docetaxel
Enzalutamide
was effective year ago but only for 7 months? Thanks
Enzalutamide
was effective year ago but only for 7 months? Thanks
Finlay66
in
Advanced Prostate Cancer
1 year ago
PCa spread to Liver
He is currently on
Enzalutamide
+ hormone injections(monthly) and has had 6 rounds of chemo (Docetaxel) finished in first week of March 2023.
He is currently on
Enzalutamide
+ hormone injections(monthly) and has had 6 rounds of chemo (Docetaxel) finished in first week of March 2023.
A-rat-22
in
Advanced Prostate Cancer
11 months ago
Clarification on ALP and LDH markers
Has been on
enzalutamide
after reoccurance until Dec 20, 2022 when he came off of it to start chemo again (docetaxel 10 rounds + prednisone is the plan). In early Oct, bone scan was clear and CT scan revealed prostate tumour and some lymph involvement.
Has been on
enzalutamide
after reoccurance until Dec 20, 2022 when he came off of it to start chemo again (docetaxel 10 rounds + prednisone is the plan). In early Oct, bone scan was clear and CT scan revealed prostate tumour and some lymph involvement.
fmoser
in
Advanced Prostate Cancer
1 year ago
Rising PSA Again! What Next? Any Thoughts?
Try to get on a drug such
enzalutamide
, apalutamide, etc.? Any thoughts that I could discuss with my Oncologist?
Try to get on a drug such
enzalutamide
, apalutamide, etc.? Any thoughts that I could discuss with my Oncologist?
MGBman
in
Advanced Prostate Cancer
1 year ago
Squalene Monooxygenase
"Furthermore, SQLE was essential for proliferation of AR-positive PCa cell lines, including abiraterone or
enzalutamide
resistant derivatives, and blocked transactivation of the AR pathway. ...
"Furthermore, SQLE was essential for proliferation of AR-positive PCa cell lines, including abiraterone or
enzalutamide
resistant derivatives, and blocked transactivation of the AR pathway. ...
pjoshea13
in
Fight Prostate Cancer
1 year ago
I would like to connect with fellow warriors that are HSPC and on Darolutamide to discuss Time to Failure, early detection assays etc...
Second generation androgen receptor antagonists and challenges in prostate cancer treatment https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304354/ " The utility of these agents has expanded with the emergence of second-generation AR antagonists, which began with the approval of
enzalutamide
in 2012
Second generation androgen receptor antagonists and challenges in prostate cancer treatment https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9304354/ " The utility of these agents has expanded with the emergence of second-generation AR antagonists, which began with the approval of
enzalutamide
in 2012
KocoPr
in
Advanced Prostate Cancer
1 year ago
Lu-177 PNT2002 SPLASH trial
The randomized study (32 weeks) will have arm A and arm B (abiraterone or
enzalutamide
) with crossover eligibility. I am concerned if I get assigned to arm B and moving the possible treatment well too late down the road if I change as requested from Abiraterone to
Enzalutamide
.
The randomized study (32 weeks) will have arm A and arm B (abiraterone or
enzalutamide
) with crossover eligibility. I am concerned if I get assigned to arm B and moving the possible treatment well too late down the road if I change as requested from Abiraterone to
Enzalutamide
.
Ollie1948
in
Advanced Prostate Cancer
2 years ago
Xtandi question
I am interested in hearing from anyone with experience in taking XTANDI® (
enzalutamide
). Has anyone else had an issue with TGA... Transient Global Amnesia? My husband has been on Xtandi for 6 weeks and has been in two different hospitals this last week.
I am interested in hearing from anyone with experience in taking XTANDI® (
enzalutamide
). Has anyone else had an issue with TGA... Transient Global Amnesia? My husband has been on Xtandi for 6 weeks and has been in two different hospitals this last week.
September221
in
Advanced Prostate Cancer
1 year ago
Pluvicto increases radiographic progression-free survival (rPFS) before chemo
https://clinicaltrials.gov/ct2/show/NCT04689828 It tested whether giving Pluvicto increases radiographic progression-free survival (rPFS) in men who: (1) have failed one of the second-line hormonals (abiraterone,
enzalutamide
, darolutamide, or apalutamide) (2) have not had taxane chemo (3) are metastatic
https://clinicaltrials.gov/ct2/show/NCT04689828 It tested whether giving Pluvicto increases radiographic progression-free survival (rPFS) in men who: (1) have failed one of the second-line hormonals (abiraterone,
enzalutamide
, darolutamide, or apalutamide) (2) have not had taxane chemo (3) are metastatic
Tall_Allen
in
Advanced Prostate Cancer
2 years ago
CCS 1477 3rd generation AR
it looks as though they’ve created a 3rd generation AR now.For when Aberaterone /
Enzalutamide
runs out of steam. Can a drug be fast tracked onto the market at a 3 year point or do the trials need at least 5 years before being approved does anyone know
it looks as though they’ve created a 3rd generation AR now.For when Aberaterone /
Enzalutamide
runs out of steam. Can a drug be fast tracked onto the market at a 3 year point or do the trials need at least 5 years before being approved does anyone know
Farn
in
Advanced Prostate Cancer
2 years ago
test Enzalutamide or Lu 177 for the first line therapy?
I wonder what is the best treatment to test lowering PSA now,
Enzalutamide
or Lu 177? I appreciate any idea.
I wonder what is the best treatment to test lowering PSA now,
Enzalutamide
or Lu 177? I appreciate any idea.
Samani
in
Advanced Prostate Cancer
2 years ago
An update on Peter Mac and Lu-177
I just wanted to update on my previous post (https://healthunlocked.com/advanced-prostate-cancer/posts/149757852/update-on-failing-
enzalutamide
).
I just wanted to update on my previous post (https://healthunlocked.com/advanced-prostate-cancer/posts/149757852/update-on-failing-
enzalutamide
).
CrocodileShoes
in
Advanced Prostate Cancer
11 months ago
Docetaxel Extends Enzalutamide Effectiveness
This is our first proof that resistance to
enzalutamide
can be reduced with docetaxel. It also shows that triplet therapy may be beneficial in patients who have already progressed to castration resistance. We would expect a larger effect if used at the first sign of castration resistance.
This is our first proof that resistance to
enzalutamide
can be reduced with docetaxel. It also shows that triplet therapy may be beneficial in patients who have already progressed to castration resistance. We would expect a larger effect if used at the first sign of castration resistance.
Tall_Allen
in
Advanced Prostate Cancer
2 years ago
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