Experiences with

Enzalutamide

They also just started me on Enzalutamide, but a few studies seem to suggest that Daralutamide may be better. I’m seeing my Oncolgist on Friday, should I ask about switching both?

I found a trustworthy place to purchase Enzalutamide, a medication for prostate cancer, at a fair price. I bought it from Oddway International, an Indian pharmaceutical distributor. They were really helpful and answered all my questions patiently.

Started Xtandi/enzalutamide about 10 days ago and this week's blood test showed AST jumped 22 to 85 within 12 days. (Normal AST range is 13-39). I do NOT have a history of liver issues, except for the Zytiga/abiraterone episode.

He was off all meds from Feb 2023 through March 2024 (PSA started rising in August 2023 - but MO essentially watched it until March 2024 before starting treatment with a half dose of Enzalutamide monotherapy). He still has has prostate and has had no radiation or any other treatment.

Among these patients, 66 had activating mutations in the androgen receptor ligand-binding domain (AR-LBD), known to confer resistance to standard treatments like abiraterone and enzalutamide. Results indicated that patients with AR-LBD mutations experienced higher response rates.

Hi I lost my dad a year ago but enzalutamide slowed the progression and shrunk the met also alleviating pain. This is taken in tablet form and offered as an alternative to chemotherapy. Hope this might help.

I had 4 oligomets in the spine, stable since a PET PSMA in November 2023 when I started Enzalutamide.

Tall Allen recently posted about a trial in which taking enzalutamide during docetaxel chemotherapy might help get the PSA down. Abiraterone failed for me recently and I’m re-challenging with docetaxel. I’m based in the UK, and NHS protocol doesn’t allow this.

Hi, Anyone experienced ENZALUTAMIDE, BE GRATEFUL FOR YOUR EXPERIENCE ON IT?

Enzalutamide stopped working earlier in the year. PSA doubling. Lesion in spine led to pathological fracture and some pressure on the spinal cord. Radiation to spine and pain relieved. Docetaxel started but discontinued due to severe allergic reaction.

Conclusion "...enzalutamide may be as efficacious as ADT as an adjuvant treatment in combination with RT. It may be better tolerated than ADT as well."

BMS-986365 is designed to inhibit androgen receptor (AR) activity through a dual mechanism of degrading the receptor and blocking its function, aiming to overcome resistance to standard AR pathway inhibitors like enzalutamide and abiraterone.

My father has had a relapse of long controlled PSA in 2022 and his PSA levels went upto 10.58; abieraterone didn't work ; he was also put on Docetaxal, he could tolerate one dose of it only and was stopped on this...he is on Enzalutamide 160 along with Wysolone 5 mg for the last 4 months...with his

Recent guidelines and studies suggest that combining docetaxel with an androgen receptor (AR) pathway inhibitor (like abiraterone, enzalutamide, or apalutamide) may offer substantial benefits even in patients with low-volume disease.

Enzalutamide stopped working. Had severe hyposensitivity reaction to docetaxel so looking at olaparib subject to gene testing. Coming off prednisalone gradually. Interested if anyone experienced similar issues with wrists and how long it lasted.

The comparator is basically the same as my current treatment with the option of changing from Abiraterone to Enzalutamide. I’m not sure of my next best move.

This doctor recently put him on Enzalutamide (two weeks now) and he's not sure whether it's making any difference yet. My brother has been on a strict ketogenic diet since being diagnosed and has also used hyperbaric oxygen therapy intermittently and is now using it five days a week.

I've seen a number of posters here and there who say they use one of the "mides" listed above with no ADT like Lupron, Eligard, Firmagan, or Orgovyx, etc. If so, did you begin that regimen after being on first level ADT for a while along with the 'mide," or did you start on the "mide" alone at the start

However I don’t regret giving BAT a go - when I enrolled in the trial I was 6 years after diagnosis, enzalutamide had failed, my PSA was high and doubling every few months. BAT was a gamble I was willing to take.

I have been trying to get my Oncologist to prescribe Enzalutamide. I have been treated with docetaxel again and thought it might re-sensitize me for another hormonal drug. Does anyone have any thoughts or experience with a situation like this.