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Enzalutamide
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Radiotherapy on Prostate. Recommendations?
on my dad who was diagnosed in Feb last year; T3b, N1 (left external iliac, bilateral common iliac, para aortic and bilateral hilar lymph nodes) M1b L5 metastases, Gleason 4+4 adenocarcinoma of prostate Presenting PSA: 97 He was initially placed on zoladex injections and was also placed on
Enzalutamide
on my dad who was diagnosed in Feb last year; T3b, N1 (left external iliac, bilateral common iliac, para aortic and bilateral hilar lymph nodes) M1b L5 metastases, Gleason 4+4 adenocarcinoma of prostate Presenting PSA: 97 He was initially placed on zoladex injections and was also placed on
Enzalutamide
Hillwalker87
in
Advanced Prostate Cancer
3 years ago
Sequencing Opportunity?
https://www.urotoday.com/conference-highlights/asco-2020/asco-2020-prostate-cancer/121890-asco-2020-transformer-bipolar-androgen-therapy-vs-
enzalutamide
-for-castration-resistant-metastatic-prostate-cancer.html
https://www.urotoday.com/conference-highlights/asco-2020/asco-2020-prostate-cancer/121890-asco-2020-transformer-bipolar-androgen-therapy-vs-
enzalutamide
-for-castration-resistant-metastatic-prostate-cancer.html
taylor123
in
Advanced Prostate Cancer
3 years ago
What if your loved one could get access to free immunotherapy treatment using Nivolumab, also known as OPDIVO?
Abiraterone,
enzalutamide
, apalitamide, darolutamide, etc) in the metastatic setting (can have received up to 2 hormonal therapies in the non-metastatic setting) You must live in either the USA or Canada Start your inquiry even if you are not sure that you qualify: malecare.org/clinical-trial
Abiraterone,
enzalutamide
, apalitamide, darolutamide, etc) in the metastatic setting (can have received up to 2 hormonal therapies in the non-metastatic setting) You must live in either the USA or Canada Start your inquiry even if you are not sure that you qualify: malecare.org/clinical-trial
Darryl
Partner
in
Prostate Cancer Caregivers
3 years ago
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What if you could get access to free immunotherapy treatment using Nivolumab, also known as OPDIVO?
Abiraterone,
enzalutamide
, apalitamide, darolutamide, etc) in the metastatic setting (can have received up to 2 hormonal therapies in the non-metastatic setting) You must live in either the USA or Canada Start your inquiry even if you are not sure that you qualify: malecare.org/clinical-trial
Abiraterone,
enzalutamide
, apalitamide, darolutamide, etc) in the metastatic setting (can have received up to 2 hormonal therapies in the non-metastatic setting) You must live in either the USA or Canada Start your inquiry even if you are not sure that you qualify: malecare.org/clinical-trial
Darryl
Partner
in
Prostate Cancer And Gay Men
3 years ago
Exclusive Fasttrak - Apply to clinical trial testing a new immunotherapy for prostate cancer!
Abiraterone,
enzalutamide
, apalitamide, darolutamide, etc) in the metastatic setting (can have received up to 2 hormonal therapies in the non-metastatic setting) You must live in either the USA or Canada Start your inquiry even if you are not sure that you qualify: https://malecare.org/clinical-trial
Abiraterone,
enzalutamide
, apalitamide, darolutamide, etc) in the metastatic setting (can have received up to 2 hormonal therapies in the non-metastatic setting) You must live in either the USA or Canada Start your inquiry even if you are not sure that you qualify: https://malecare.org/clinical-trial
Darryl
Partner
in
Advanced Prostate Cancer
3 years ago
General Advice from You Brain boxes 😉
background info on my dad who was diagnosed in Feb last year; T3b, N1 (left external iliac, bilateral common iliac, para aortic and bilateral hilar lymph nodes) M1b L5 metastases, Gleason 4+4 adenocarcinoma of prostate Presenting PSA: 97 He was initially placed on zoladex injections and was also placed on
Enzalutamide
background info on my dad who was diagnosed in Feb last year; T3b, N1 (left external iliac, bilateral common iliac, para aortic and bilateral hilar lymph nodes) M1b L5 metastases, Gleason 4+4 adenocarcinoma of prostate Presenting PSA: 97 He was initially placed on zoladex injections and was also placed on
Enzalutamide
Hillwalker87
in
Advanced Prostate Cancer
3 years ago
Target PSA value?
I got spinal compressive surgery Aug. 1 and was started on lupron +
enzalutamide
(Xtandi). Since then my PSA and been falling and this week is down to 0.3 ng/mL. I am also doing a lot of alternative medicine as a companion and want to go off hormone blockers and cycle if needed once i hit nadir.
I got spinal compressive surgery Aug. 1 and was started on lupron +
enzalutamide
(Xtandi). Since then my PSA and been falling and this week is down to 0.3 ng/mL. I am also doing a lot of alternative medicine as a companion and want to go off hormone blockers and cycle if needed once i hit nadir.
Biteson62
in
Advanced Prostate Cancer
3 years ago
Planned Chemo tomorrow need suggestion and information
As PSA(200) started increasing doctor asked to go on
Enzalutamide
, initially for 1 month it worked, and thereafter PSA started increasing. for the past 3 months, we were on
Enzalutamide
. Now PSA is 517. Doctor asked to go for Chemo I have attached his prescription.
As PSA(200) started increasing doctor asked to go on
Enzalutamide
, initially for 1 month it worked, and thereafter PSA started increasing. for the past 3 months, we were on
Enzalutamide
. Now PSA is 517. Doctor asked to go for Chemo I have attached his prescription.
Vasanta
in
Advanced Prostate Cancer
4 years ago
EMBARK trial results already available?
EMBARK is a randomized Phase 3 study of
enzalutamide
plus leuprolide,
enzalutamide
monotherapy, and leuprolide alone in men with high-risk non-metastatic HSPC.
EMBARK is a randomized Phase 3 study of
enzalutamide
plus leuprolide,
enzalutamide
monotherapy, and leuprolide alone in men with high-risk non-metastatic HSPC.
GP24
in
Advanced Prostate Cancer
4 years ago
Neuroendocrine cells.
GnRH agonists and antagonists), inhibiting intratumoral androgen synthesis (i.e. abiraterone acetate) or competitive inhibition of AR itself (i.e.
enzalutamide
). This treatment, although initially effective, eventually fails after the tumor cells develop various mechanisms of resistance.
GnRH agonists and antagonists), inhibiting intratumoral androgen synthesis (i.e. abiraterone acetate) or competitive inhibition of AR itself (i.e.
enzalutamide
). This treatment, although initially effective, eventually fails after the tumor cells develop various mechanisms of resistance.
pjoshea13
in
Advanced Prostate Cancer
3 years ago
BAT: transformer trial
(Testosterone Revival Abolishes Negative Symptoms, Fosters Objective Response and Modulates
Enzalutamide
Resistance (Transformer) – what violence we do to language in science!) In this one they took about 200 asymptomatic patients who had progressed on abiraterone and had not taken
enzalutamide
.
(Testosterone Revival Abolishes Negative Symptoms, Fosters Objective Response and Modulates
Enzalutamide
Resistance (Transformer) – what violence we do to language in science!) In this one they took about 200 asymptomatic patients who had progressed on abiraterone and had not taken
enzalutamide
.
kaptank
in
Advanced Prostate Cancer
4 years ago
New York Times article on the recent Lutetium-177–PSMA-617 study [VISION] + NEJM paper
., abiraterone and
enzalutamide
).
., abiraterone and
enzalutamide
).
pjoshea13
in
Advanced Prostate Cancer
3 years ago
Advice and Opinions would be great.
*
Enzalutamide
(Xtandi)

 * Ketoconazole * High dose Testosterone to shock the PCa cells.
*
Enzalutamide
(Xtandi)

 * Ketoconazole * High dose Testosterone to shock the PCa cells.
taylor123
in
Advanced Prostate Cancer
4 years ago
Update to Can't treat what we can't see
Following is from the After Visit Summary: We discussed a recommendation for
enzalutamide
at this point - while it may have a lower response rate compared to docetaxel, especially after progression on abiraterone therapy, the toxicity of docetaxel is significantly greater, especially in the context
Following is from the After Visit Summary: We discussed a recommendation for
enzalutamide
at this point - while it may have a lower response rate compared to docetaxel, especially after progression on abiraterone therapy, the toxicity of docetaxel is significantly greater, especially in the context
SF22
in
Advanced Prostate Cancer
4 years ago
To treat or not to treat: is it acceptable to avoid active therapies in advanced prostate cancer today?
Furthermore, two more recent phase III RCTs have shown that adding
enzalutamide
[9] or apalutamide [14] to ADT improves OS in comparison with ADT alone.
Furthermore, two more recent phase III RCTs have shown that adding
enzalutamide
[9] or apalutamide [14] to ADT improves OS in comparison with ADT alone.
pjoshea13
in
Advanced Prostate Cancer
4 years ago
Title :Enzalutamide and Niclosamide in Treating Patients With Recurrent or Metastatic Castration-Resistant Prostate Cancer
With all the interest in my last post I thought some might be interested in this: https://www.cureitt.com/trialdetails?nctid=NCT03123978 Maybe someone out there could explain the difference between niclosamide and Fenbendazole, they are both used for deworming dogs.
With all the interest in my last post I thought some might be interested in this: https://www.cureitt.com/trialdetails?nctid=NCT03123978 Maybe someone out there could explain the difference between niclosamide and Fenbendazole, they are both used for deworming dogs.
Magnus1964
in
Advanced Prostate Cancer
4 years ago
I vitro evidence for effectiveness of Simvastatin Metformin combination against Enzalutamide resistant CRPC
The second generation androgen receptor (AR) antagonist
enzalutamide
(ENZU) exhibits survival advantage in CRPC patients, however ∼30% of patients develop resistance overtime activating AR in these tumors.
The second generation androgen receptor (AR) antagonist
enzalutamide
(ENZU) exhibits survival advantage in CRPC patients, however ∼30% of patients develop resistance overtime activating AR in these tumors.
Graham49
in
Advanced Prostate Cancer
4 years ago
Sipuleucel-T boosts survival versus abiraterone or enzalutamide alone in real-world mCRPC analysis
The median OS was improved by 14.5 months with sipuleucel-T https://www.urologytimes.com/view/sipuleucel-t-boosts-survival-versus-abiraterone-or-
enzalutamide
-alone-in-real-world-mcrpc-analysis
The median OS was improved by 14.5 months with sipuleucel-T https://www.urologytimes.com/view/sipuleucel-t-boosts-survival-versus-abiraterone-or-
enzalutamide
-alone-in-real-world-mcrpc-analysis
George71
in
Advanced Prostate Cancer
4 years ago
Enzalutamide and headaches
I've recently started on
enzalutamide
. I am experiencing headaches since I started taking this drug. Some evenings I'm ok, others I get the headache. I spoke to the hospital and they told me, come back to us if this persists. They think it might be my body getting used to enza.
I've recently started on
enzalutamide
. I am experiencing headaches since I started taking this drug. Some evenings I'm ok, others I get the headache. I spoke to the hospital and they told me, come back to us if this persists. They think it might be my body getting used to enza.
londoncyclist48
in
Advanced Prostate Cancer
4 years ago
Starting enzalutamide
MO recommends adding
enzalutamide
to current ADT regimen since PSA has gradually risen to 4.4 from 2,9 in 3 months. Original idea was for darolutamide but insurance disallowed. Passed on Zytinga with the prednisone due to afib and mild heart failure.
MO recommends adding
enzalutamide
to current ADT regimen since PSA has gradually risen to 4.4 from 2,9 in 3 months. Original idea was for darolutamide but insurance disallowed. Passed on Zytinga with the prednisone due to afib and mild heart failure.
33947
in
Advanced Prostate Cancer
4 years ago
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