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Unsure of best option in early prostate cancer diagnosis.
I have had PSA tests annually for 10 years and in Oct 2023 had an elevated 6.42 result. Was referred to a urologist, whom performed a DRE. There was prostate enlargement but no tumor discovered through DRE. After discussing several options, I decided to have a biopsy on Nov 21, 2023. Dec 5, 2023,
I have had PSA tests annually for 10 years and in Oct 2023 had an elevated 6.42 result. Was referred to a urologist, whom performed a DRE. There was prostate enlargement but no tumor discovered through DRE. After discussing several options, I decided to have a biopsy on Nov 21, 2023. Dec 5, 2023,
cobrasc429
in
Advanced Prostate Cancer
3 months ago
I am still struggling with treatment decisions - Help please.
I am struggling to decide on my treatment. The main point of conflict is HT or not, and LDR Brachytherapy (if I am eligible - because of a previous HOLEP) or IMRT. I also wonder if I should push hard for a 10-day earlier consultation at the risk of bad feeling. I welcome advice. In the UK - Referral
I am struggling to decide on my treatment. The main point of conflict is HT or not, and LDR Brachytherapy (if I am eligible - because of a previous HOLEP) or IMRT. I also wonder if I should push hard for a 10-day earlier consultation at the risk of bad feeling. I welcome advice. In the UK - Referral
Nordman
in
Advanced Prostate Cancer
4 months ago
Know your Biomarker … Know Your Mutation
KRAS mutation in colorectal cancer is an abnormal change in the KRAS gene, which is involved in controlling cell growth and survival. 40% of CRC has a KRAS mutation. There are more than 25 ongoing clinical trials studying treatments for KRAS-mutated colorectal cancer. Learn more about the KRAS biomarker
KRAS mutation in colorectal cancer is an abnormal change in the KRAS gene, which is involved in controlling cell growth and survival. 40% of CRC has a KRAS mutation. There are more than 25 ongoing clinical trials studying treatments for KRAS-mutated colorectal cancer. Learn more about the KRAS biomarker
GCCA-Survivor
Administrator
in
Colon Cancer Connected
4 months ago
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Staying on Ibrance & Anastrozole after 2 recurrences
I’ve been on Ibrance and Anastrozole for the last 6 years for metastatic endometrial cancer. I started out on the Ibrance125 mg and after a couple of years, had a problem recovering on the week off, so my dose was reduced to 100 mg. By spring this year, the counts could not recover on the week off,
I’ve been on Ibrance and Anastrozole for the last 6 years for metastatic endometrial cancer. I started out on the Ibrance125 mg and after a couple of years, had a problem recovering on the week off, so my dose was reduced to 100 mg. By spring this year, the counts could not recover on the week off,
Merma
in
SHARE Metastatic Breast Cancer
4 months ago
Squamous cell Carcinoma
HERE’S WHAT TO LOOK OUT FOR: Small, hard white or skin coloured lumps. SCCs often first appear on the skin like this. A persistent, scaly red patch with irregular borders. These can sometimes crust or bleed. An elevated growth with a central depression A growth of this type may rapidly increase
HERE’S WHAT TO LOOK OUT FOR: Small, hard white or skin coloured lumps. SCCs often first appear on the skin like this. A persistent, scaly red patch with irregular borders. These can sometimes crust or bleed. An elevated growth with a central depression A growth of this type may rapidly increase
SkcinHQ
Partner
in
Skin Cancer UK
4 months ago
Orchiectomy and Psa
Can anyone who has had Bilateral Ochiectomy tell me if there is a certain psa level required before surgery can be done. Thanks Guys Knittingque
Can anyone who has had Bilateral Ochiectomy tell me if there is a certain psa level required before surgery can be done. Thanks Guys Knittingque
Knittingque
in
Advanced Prostate Cancer
4 months ago
liver Mets, Pluvicto failed
diagnosed 2021, spread to distant lymph nodes. Castrate resistant within 6 months. Had platinum based chemo. Stabilized for bit. 4 Pluvicto treatments. PSA went from 4 to 70. Latest scans show new mets to liver. Genetic testing shows ATM mutation. Where to go from here?
diagnosed 2021, spread to distant lymph nodes. Castrate resistant within 6 months. Had platinum based chemo. Stabilized for bit. 4 Pluvicto treatments. PSA went from 4 to 70. Latest scans show new mets to liver. Genetic testing shows ATM mutation. Where to go from here?
mysticmini
in
Advanced Prostate Cancer
4 months ago
Brain Lipoma Symptoms
Hi, I'm looking for others who have this rare type of benign brain tumour. What are some of your symptoms and what has been your journey in getting help. I have a lipoma in the middle of my brain and have headaches, limb weakness and some other issues but can't find anyone to relate to..... thank you
Hi, I'm looking for others who have this rare type of benign brain tumour. What are some of your symptoms and what has been your journey in getting help. I have a lipoma in the middle of my brain and have headaches, limb weakness and some other issues but can't find anyone to relate to..... thank you
Flower589
in
Headway
4 months ago
Heliocare
I am going to post this and everyone can do with the information what they want. I wanted to bring this dietary supplement to everyone’s attention especially those of us who take meds that put us at higher risks for skin cancer from our meds. Heliocare is a dietary supplement I have kept seen coming
I am going to post this and everyone can do with the information what they want. I wanted to bring this dietary supplement to everyone’s attention especially those of us who take meds that put us at higher risks for skin cancer from our meds. Heliocare is a dietary supplement I have kept seen coming
KLCTJC
in
MPN Voice
4 months ago
Help, bad Decipher results, this changes everything, please advise (NE WI area but will travel)
Hi everyone~ I just wrote recently but this Decipher test seems to have up-ended our lives. My husband, 75, overweight w/Watchman, was dx'ed late Nov. w/what was originally classified as Favorable Risk Intermediate after random biopsy; we went to a urologic oncologist out of Froedtert in Milwaukee
Hi everyone~ I just wrote recently but this Decipher test seems to have up-ended our lives. My husband, 75, overweight w/Watchman, was dx'ed late Nov. w/what was originally classified as Favorable Risk Intermediate after random biopsy; we went to a urologic oncologist out of Froedtert in Milwaukee
AliceinW57
in
Prostate Cancer Network
4 months ago
Surgery vs SBRT Cyberknife
I posted this in the Advanced PC group and shouldn't have, as my Hubs is not in an advanced stage. Posting here in hopes of more input! I apologize if you are in the other group and have already seen this! Hubs diagnosed 11/15/23. 2 of 12 positive. Gleason 6 and 7. PSA 3.7-4.2. Met with Surgeon first
I posted this in the Advanced PC group and shouldn't have, as my Hubs is not in an advanced stage. Posting here in hopes of more input! I apologize if you are in the other group and have already seen this! Hubs diagnosed 11/15/23. 2 of 12 positive. Gleason 6 and 7. PSA 3.7-4.2. Met with Surgeon first
Pride123
in
Prostate Cancer Network
4 months ago
Bleeding when opening the bowels
does anyone else get this? I had to have an emergency appointment today as I went to the toilet and when I opened my bowels and looked in the toilet, the water and bowl were full of blood! I had confirmed stage 2 endo on my bladder and ovary, I’ve also had mumtiple colonoscopies, sigmoidoscopies, endoscopies
does anyone else get this? I had to have an emergency appointment today as I went to the toilet and when I opened my bowels and looked in the toilet, the water and bowl were full of blood! I had confirmed stage 2 endo on my bladder and ovary, I’ve also had mumtiple colonoscopies, sigmoidoscopies, endoscopies
nikogirl18
in
Endometriosis UK
4 months ago
biopsy - fragmented cores and progression risk
I had 3 biopsies from January 2020 to July 2022. The first two almost identical being Gleason 3+4 with <10% 4. However 6 months post HIFU it was Gleason 9 with 4+5 with 10% 5 and 70% 5 (see below). I am curious as the cores are fragmented and so it’s hard to know what this means and if it makes any
I had 3 biopsies from January 2020 to July 2022. The first two almost identical being Gleason 3+4 with <10% 4. However 6 months post HIFU it was Gleason 9 with 4+5 with 10% 5 and 70% 5 (see below). I am curious as the cores are fragmented and so it’s hard to know what this means and if it makes any
SimMartin
in
Advanced Prostate Cancer
4 months ago
Hello friends. It's me again. Bone Biopsy + Dr. nonsense.
Ok, so I have not posted my situation for awhile because I was/am still waiting for tests. Quick review-Luminal A Hr Es+ 90-100% Pr+80-90%,ki67<10% HER2 neg(2+,sish neg) her2 low, I guess. This was the original in 2016. Had chemo, rads, anastrozle up to 2019 when dx mbc. Ibrance + fasoldex, then xeloda
Ok, so I have not posted my situation for awhile because I was/am still waiting for tests. Quick review-Luminal A Hr Es+ 90-100% Pr+80-90%,ki67<10% HER2 neg(2+,sish neg) her2 low, I guess. This was the original in 2016. Had chemo, rads, anastrozle up to 2019 when dx mbc. Ibrance + fasoldex, then xeloda
Hopeful4Cure
in
SHARE Metastatic Breast Cancer
4 months ago
Please send me some positivity.
I have just had the results of my CT scan and I have been told I have a recurrance in one para-aortic lymph node. I will either need surgery (if they can), chemo or radiotherapy. I'm so scared as this is my first recurrence from Stage 4 ovarian cancer and I'm only 56 and have two teenagers. I can't
I have just had the results of my CT scan and I have been told I have a recurrance in one para-aortic lymph node. I will either need surgery (if they can), chemo or radiotherapy. I'm so scared as this is my first recurrence from Stage 4 ovarian cancer and I'm only 56 and have two teenagers. I can't
Nectirlawone
in
My Ovacome
4 months ago
And more ASCO GU 2024 phase 3 trial
Data will be presented at ASCO GU 2024 but looks promising "In combination with immunotherapy, Cabometyx is delivering long-term survival benefits today for people living with renal cell carcinoma worldwide, while also showcasing future potential in metastatic castration-resistant prostate cancer, an
Data will be presented at ASCO GU 2024 but looks promising "In combination with immunotherapy, Cabometyx is delivering long-term survival benefits today for people living with renal cell carcinoma worldwide, while also showcasing future potential in metastatic castration-resistant prostate cancer, an
Maxone73
in
Advanced Prostate Cancer
4 months ago
Abnormalities on the CT 6 months after Chemo (while on Niraparib) CA125 at 4.9, anyone same experience?
Dear ladies, Background : IVB HSOC Jan 2023, Debulking April 23, last chemo June 23, on Niraparib since Aug 23, diagnosed at 40 yo (now 41). Now CT shows small abnormalities: They saw 2 nodular abnormalities on CT scan, (16mm) suspecting local recurrence but they do not know for sure. Also they noticed
Dear ladies, Background : IVB HSOC Jan 2023, Debulking April 23, last chemo June 23, on Niraparib since Aug 23, diagnosed at 40 yo (now 41). Now CT shows small abnormalities: They saw 2 nodular abnormalities on CT scan, (16mm) suspecting local recurrence but they do not know for sure. Also they noticed
Beatyourself
in
My Ovacome
4 months ago
Surgery vs SBRT Cyberknife
Hubs diagnosed 11/15/23. 2 of 12 positive. Gleason 6 and 7. PSA 3.7-4.2. Met with Surgeon first, "slow growing, non aggressive" he believes is contained by looking at margins and pathology. Met with Radiology Oncologist, "favorable intermediate risk, non aggressive" he believes it is contained. Both
Hubs diagnosed 11/15/23. 2 of 12 positive. Gleason 6 and 7. PSA 3.7-4.2. Met with Surgeon first, "slow growing, non aggressive" he believes is contained by looking at margins and pathology. Met with Radiology Oncologist, "favorable intermediate risk, non aggressive" he believes it is contained. Both
Pride123
in
Advanced Prostate Cancer
4 months ago
clinical trial: ATR inhibitor for ATM mutated solid tumors
in vivo and in vitro studies suggest that ATR inhibitors work better than PARP inhibitors for people with ATM gene mutations…but together they may work even better I hope to find more data about this clinical trial https://www.biospace.com/article/releases/aprea-therapeutics-announces-dosing-of-first-patient-in-phase
in vivo and in vitro studies suggest that ATR inhibitors work better than PARP inhibitors for people with ATM gene mutations…but together they may work even better I hope to find more data about this clinical trial https://www.biospace.com/article/releases/aprea-therapeutics-announces-dosing-of-first-patient-in-phase
Maxone73
in
Advanced Prostate Cancer
4 months ago
Orchidectomy vs ADT
For anyone who had the bilateral orchidectomy, I would like some advice for my husband. When was it done? Before or after BCR occurred? What are the side effects? Do you take any other ADT meds after? How is your QOL and is there anything you'd do differently. He had RP in Dec 2021. No other treatment
For anyone who had the bilateral orchidectomy, I would like some advice for my husband. When was it done? Before or after BCR occurred? What are the side effects? Do you take any other ADT meds after? How is your QOL and is there anything you'd do differently. He had RP in Dec 2021. No other treatment
tn12
in
Advanced Prostate Cancer
4 months ago
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