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Dopamine links to some AI diseases and maybe PMR/GCA ?
[i]'Dopamine has emerged as a fundamental regulator of inflammation. In this regard, it has been shown that dopaminergic signalling pathways are key players promoting homeostasis between the central nervous system and the immune system. Dysregulation in the dopaminergic system affects both innate and
[i]'Dopamine has emerged as a fundamental regulator of inflammation. In this regard, it has been shown that dopaminergic signalling pathways are key players promoting homeostasis between the central nervous system and the immune system. Dysregulation in the dopaminergic system affects both innate and
Rimmy
in
PMRGCAuk
5 years ago
Why Are Forum Members Who are Using HDT/B-1 Starting To Have Symptom Increases After 6 ~ 18 Months Of Being Stable With B-1/HDT ?
I've been answering questions about this more and more on this forum as members start to exceed 6 months of HDT use. I decided to make a post about this problem so members can search/reference this post as needed. According to Dr. Costantini, his theory is that thiamine/B-1 at higher dosing is reducing
I've been answering questions about this more and more on this forum as members start to exceed 6 months of HDT use. I decided to make a post about this problem so members can search/reference this post as needed. According to Dr. Costantini, his theory is that thiamine/B-1 at higher dosing is reducing
chartist
in
Cure Parkinson's
5 years ago
Dopamine fast
NYT week-end read https://nl.nytimes.com/f/newsletter/IlFnNz4tLi5GAven_n-FZA~~/AAAAAQA~/RgRfqHq9P0TYaHR0cHM6Ly93d3cubnl0aW1lcy5jb20vMjAxOS8xMS8wNy9zdHlsZS9kb3BhbWluZS1mYXN0aW5nLmh0bWw_dGU9MSZubD1ldmVuaW5nLWJyaWVmaW5nJmVtYz1lZGl0X25lXzIwMTkxMTA4P2NhbXBhaWduX2lkPTU3Jmluc3RhbmNlX2lkPTEzNzQzJnNlZ21lbnRfaWQ9MTg2NTUmdXNlcl9pZD03MTk2MmRiMDY5ZWQxYmRmZjVmNTY0N2YxMGFiMDZkYSZyZWdpX2lkPTU2MDUwNTE0VwNueXRCCgAdvfXFXfhY5ElSFGluZm9tYXJjZXRAZ21haWwuY29tWAQAAAAA
NYT week-end read https://nl.nytimes.com/f/newsletter/IlFnNz4tLi5GAven_n-FZA~~/AAAAAQA~/RgRfqHq9P0TYaHR0cHM6Ly93d3cubnl0aW1lcy5jb20vMjAxOS8xMS8wNy9zdHlsZS9kb3BhbWluZS1mYXN0aW5nLmh0bWw_dGU9MSZubD1ldmVuaW5nLWJyaWVmaW5nJmVtYz1lZGl0X25lXzIwMTkxMTA4P2NhbXBhaWduX2lkPTU3Jmluc3RhbmNlX2lkPTEzNzQzJnNlZ21lbnRfaWQ9MTg2NTUmdXNlcl9pZD03MTk2MmRiMDY5ZWQxYmRmZjVmNTY0N2YxMGFiMDZkYSZyZWdpX2lkPTU2MDUwNTE0VwNueXRCCgAdvfXFXfhY5ElSFGluZm9tYXJjZXRAZ21haWwuY29tWAQAAAAA
marcet
in
Cure Parkinson's
5 years ago
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Dopamine Agonists no longer first line treatment of RLS
Can anyone point me in the direction of reputable UK, US national health guidelines regarding the above? Also approaches to withdrawing off DAs. I'm wanting to arm myself before visiting my new doctor. Thanks.
Can anyone point me in the direction of reputable UK, US national health guidelines regarding the above? Also approaches to withdrawing off DAs. I'm wanting to arm myself before visiting my new doctor. Thanks.
YodaDog
in
Restless Legs Syndrome
5 years ago
Do other dopamine boosters also cause augmentation?
I’m experiencing really bad RLS augmentation from supplementing with L-Dopa for three months, but wondering if I switch to other dopamine boosters such as Chlonine, Uridine, L-theanine, will the effect be the same? For context, this is what they specifically do: https://www.mindlabpro.com/blogs/nootropics
I’m experiencing really bad RLS augmentation from supplementing with L-Dopa for three months, but wondering if I switch to other dopamine boosters such as Chlonine, Uridine, L-theanine, will the effect be the same? For context, this is what they specifically do: https://www.mindlabpro.com/blogs/nootropics
RoDomHarr
in
Restless Legs Syndrome
5 years ago
Scientific information about RLS
If anyone is looking for GREAT info on RLS , and what Dr, Christopher Earley says can be the 3 causes........go to this web site. www.hopkinsmedicine.org The RLS Quality Care Center is there at Johns Hopkins. The 3 main causes listed are "brain concentrations of iron", "brain concentrations of dopamine
If anyone is looking for GREAT info on RLS , and what Dr, Christopher Earley says can be the 3 causes........go to this web site. www.hopkinsmedicine.org The RLS Quality Care Center is there at Johns Hopkins. The 3 main causes listed are "brain concentrations of iron", "brain concentrations of dopamine
nightdancer
in
Restless Legs Syndrome
5 years ago
Causes of rls continued...
Sorry about interruption of message.. Low iron can lead to low dopamine so personally I'm eating as much dopamine foods as I can. Also other health issues can trigger rls.. such as.. Underactive thyroid.. Kidney disease.. Diabetes.. Parkinson's.. Rumatoid arthritis.. Fibromyalgia.. Some drugs can, such
Sorry about interruption of message.. Low iron can lead to low dopamine so personally I'm eating as much dopamine foods as I can. Also other health issues can trigger rls.. such as.. Underactive thyroid.. Kidney disease.. Diabetes.. Parkinson's.. Rumatoid arthritis.. Fibromyalgia.. Some drugs can, such
janland
in
Restless Legs Syndrome
5 years ago
Dopamine Receptor-targeting Drugs for New Dopamine-related Therapies for Fibrosis
Post by MPN-MATE Admin » Wed Oct 30, 2019 11:37 pm Hey everyone... :D This new piece of Research into Fibrosis may hold some fascinating insights in time... At this early juncture, it is only based upon 'Mouse-modelling' however, it really does make for an interesting read, and I hope that some of
Post by MPN-MATE Admin » Wed Oct 30, 2019 11:37 pm Hey everyone... :D This new piece of Research into Fibrosis may hold some fascinating insights in time... At this early juncture, it is only based upon 'Mouse-modelling' however, it really does make for an interesting read, and I hope that some of
socrates_8
in
MPN Voice
5 years ago
New insights into addictive behaviour caused by dopamine replacement therapy
"They created a kind of wiring map of the brain and found that those who had negative behavioural reactions to the medication had one of two things in common. 'We took circuits in the brain that we know have underlying important behaviours and two of those behaviours are choosing and stopping
"They created a kind of wiring map of the brain and found that those who had negative behavioural reactions to the medication had one of two things in common. 'We took circuits in the brain that we know have underlying important behaviours and two of those behaviours are choosing and stopping
jeffreyn
in
Cure Parkinson's
5 years ago
Low dose aspirin?
Not sure if anyone had seen this study, but wanted to post it just in case - "Aspirin: Barking up the right tree?" which presents a study on mice which may not translate to the same results in humans, however conclusion was very intriguing: "Recently researchers have found that low doses of the pain
Not sure if anyone had seen this study, but wanted to post it just in case - "Aspirin: Barking up the right tree?" which presents a study on mice which may not translate to the same results in humans, however conclusion was very intriguing: "Recently researchers have found that low doses of the pain
faridaro
in
Cure Parkinson's
5 years ago
Been on Elvanse (Vyvanse) for nearly three months, about to switch to Concerta XL for a trial...
Hi there (new here!) Have been on Elvanse for three months now - slowly titrating up from 20mg to maximum dose of 70mg. It stays in my system comfortably for at least 10 hours, and the main indication I have that it's wearing off is my RLS starts up! No major crash like some have described with other
Hi there (new here!) Have been on Elvanse for three months now - slowly titrating up from 20mg to maximum dose of 70mg. It stays in my system comfortably for at least 10 hours, and the main indication I have that it's wearing off is my RLS starts up! No major crash like some have described with other
RaphaeliteGirl
in
CHADD's Adult ADHD Support
5 years ago
How many Dopamine meds have you had
I have had Pramapixole Requip Xl Ropineral and the patch , Pregablin Gabapentin Tramodol and Amatriptyline
I have had Pramapixole Requip Xl Ropineral and the patch , Pregablin Gabapentin Tramodol and Amatriptyline
beady3
in
Restless Legs Syndrome
5 years ago
Phenylalanine for depression
I want to share my discovery of phenylalanine with you , it is an.amino acid it has been proven to help with depression it increases dopamine in the brain so it is not recommended for people with bipolar disorder also some people who can't process phenylalanine - PKU Phenylalanine is also an immune suppressor
I want to share my discovery of phenylalanine with you , it is an.amino acid it has been proven to help with depression it increases dopamine in the brain so it is not recommended for people with bipolar disorder also some people who can't process phenylalanine - PKU Phenylalanine is also an immune suppressor
lillyofthevalley37
in
Anxiety and Depression Support
5 years ago
Has anyone tried Targin?
Just want to say a big thank you to all of you here . It is powerful support for me, and much needed as I continue to suffer after stopping Dopamine Agonists My GP has me currently on Pregabalin 225 mg at 6 pm and Targin 10 mg at bedtime.I am still up and down all night walking etc and then very
Just want to say a big thank you to all of you here . It is powerful support for me, and much needed as I continue to suffer after stopping Dopamine Agonists My GP has me currently on Pregabalin 225 mg at 6 pm and Targin 10 mg at bedtime.I am still up and down all night walking etc and then very
picol
in
Restless Legs Syndrome
5 years ago
MY STORY sad but true
At 4:00 today I had my appointment with Dr. Berkowski at the University of Michigan . I saw him until 6:00 and I just got home at 9:00. I am exhausted and I really don't know how I feel yet. Apparently my brain doesn't absorb iron as it should. Years ago I became anemic and developed RLS and was
At 4:00 today I had my appointment with Dr. Berkowski at the University of Michigan . I saw him until 6:00 and I just got home at 9:00. I am exhausted and I really don't know how I feel yet. Apparently my brain doesn't absorb iron as it should. Years ago I became anemic and developed RLS and was
sweetiepye
in
Restless Legs Syndrome
5 years ago
Dopamine check
OK ok ok everyone. I've googled it now so everytime I see it now here I ll know about it & won't be so ignorant. (&cause controversey) lol
OK ok ok everyone. I've googled it now so everytime I see it now here I ll know about it & won't be so ignorant. (&cause controversey) lol
Sara_2611
in
Restless Legs Syndrome
5 years ago
Dopamine knowledge
OK! OK!! OK!! Everyone!! Lol I ll Google it just to show you that I'm not the ignoramus you think me to be lol - on this subject I mean &Yes I do know its mentioned on this site. Just because it's mentioned every day on this site doesn't mean I have to know much about it lol
OK! OK!! OK!! Everyone!! Lol I ll Google it just to show you that I'm not the ignoramus you think me to be lol - on this subject I mean &Yes I do know its mentioned on this site. Just because it's mentioned every day on this site doesn't mean I have to know much about it lol
Sara_2611
in
Restless Legs Syndrome
5 years ago
Dopamine vs Dopamine agonist. May someone explain the technical mechanism of action in the brain? Pros/Cons of these therapy methods?
Effectiveness of each method and how it compares. What about side effects? Which one is less harmful?
Effectiveness of each method and how it compares. What about side effects? Which one is less harmful?
marnegro
in
Cure Parkinson's
5 years ago
No real answer.
Did anyone watch chanel 5 programme on sleep disorders ? Dopamine angst ....no mention of augmentation !
Did anyone watch chanel 5 programme on sleep disorders ? Dopamine angst ....no mention of augmentation !
pilateskid
in
Restless Legs Syndrome
5 years ago
RLS / new member intro / alcohol Q&A
I have a question (it will be at the bottom ) and i have a post . Sorry for the length . Please bare with me . First I’m new to this group but I’m thankful that I found it . My name is Denise Tibbs . I’m 25, married , and have 2 kids . I’m the manager of a vet clinic and I am the boss and founder
I have a question (it will be at the bottom ) and i have a post . Sorry for the length . Please bare with me . First I’m new to this group but I’m thankful that I found it . My name is Denise Tibbs . I’m 25, married , and have 2 kids . I’m the manager of a vet clinic and I am the boss and founder
D_Tibbs211
in
Restless Legs Syndrome
5 years ago
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