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Bomedemstat in Patients With Polycythemia Vera
This is a Phase 2 open label study of an orally administered LSD1 inhibitor, bomedemstat (IMG-7289), in patients with polycythemia vera. This study investigates the following: – The safety and tolerability of bomedemstat – The pharmacodynamic effect of bomedemstat »Participating in This Clinical Trial
This is a Phase 2 open label study of an orally administered LSD1 inhibitor, bomedemstat (IMG-7289), in patients with polycythemia vera. This study investigates the following: – The safety and tolerability of bomedemstat – The pharmacodynamic effect of bomedemstat »Participating in This Clinical Trial
Manouche
in
MPN Voice
2 years ago
It's spread to liver and bones. Any advice?
Good morning friends. @I was two treatments in to a clinical trial but the CAT scan yesterday discovered lesions in the liver, bone metestases and some adenopathies. I have been referred back to my own oncologist but in the meantime I am in limbo, wondering if this is the end of the line or if there
Good morning friends. @I was two treatments in to a clinical trial but the CAT scan yesterday discovered lesions in the liver, bone metestases and some adenopathies. I have been referred back to my own oncologist but in the meantime I am in limbo, wondering if this is the end of the line or if there
Riverflo
in
My Ovacome
2 years ago
Do you have persistent or long-standing AF?
We are currently recruiting a small number of volunteers to form a panel to discuss your personal experiences of living with the condition. You must be aged 70+, live in the UK, and have received a confirmed diagnosis of persistent or long-standing AF. You may also be taking medications, have previously
We are currently recruiting a small number of volunteers to form a panel to discuss your personal experiences of living with the condition. You must be aged 70+, live in the UK, and have received a confirmed diagnosis of persistent or long-standing AF. You may also be taking medications, have previously
TracyAdmin
ArrhythmiaAlliance
in
Arrhythmia Alliance
1 year ago
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Do you have persistent or long-standing AF?
We are currently recruiting a small number of volunteers to form a panel to discuss your personal experiences of living with the condition. You must be aged 70+, live in the UK, and have received a confirmed diagnosis of persistent or long-standing AF. You may also be taking medications, have previously
We are currently recruiting a small number of volunteers to form a panel to discuss your personal experiences of living with the condition. You must be aged 70+, live in the UK, and have received a confirmed diagnosis of persistent or long-standing AF. You may also be taking medications, have previously
TracyAdmin
Partner
in
AF Association
1 year ago
Third PSMA PET indicator may be approved by FDA
F18-rhPSMA-7, is an experimental PET indicators that is cleared quickly from the bladder, and is among the best so far. In a clinical trial, it was able to find prostate cancer metastases in 71% of men with post-prostatectomy PSA between 0.2-0.5 ng/ml, which is about 50% greater than the detection rate
F18-rhPSMA-7, is an experimental PET indicators that is cleared quickly from the bladder, and is among the best so far. In a clinical trial, it was able to find prostate cancer metastases in 71% of men with post-prostatectomy PSA between 0.2-0.5 ng/ml, which is about 50% greater than the detection rate
Tall_Allen
in
Advanced Prostate Cancer
2 years ago
Genetic test results (or not?)
I've been waiting 6 weeks for the results of genetic tests of my prostate tumour biopsy sample and blood to see if I qualify for the Amplitude clinical trial. They finally came through today but were disappointing in that they have told me very little! (Apart from I'm not eligible for the trial). The
I've been waiting 6 weeks for the results of genetic tests of my prostate tumour biopsy sample and blood to see if I qualify for the Amplitude clinical trial. They finally came through today but were disappointing in that they have told me very little! (Apart from I'm not eligible for the trial). The
Benkaymel
in
Advanced Prostate Cancer
2 years ago
Recovery while manic
Today is day 9 of my recovery. Since my last post on this log. I am going through the withdrawal process and I feel like I need to score. It sucks to say "I like to get high when I'm feeling low". I've been working on myself for 12yrs now. And these days I'm really wanting to quit my old habits and grow
Today is day 9 of my recovery. Since my last post on this log. I am going through the withdrawal process and I feel like I need to score. It sucks to say "I like to get high when I'm feeling low". I've been working on myself for 12yrs now. And these days I'm really wanting to quit my old habits and grow
Rayman559
in
Above & Beyond
1 year ago
diagnosed in Feb. with atrial flutter at ED
good morning, My name is Patrick McConnell and I live in Burlington Ontario Canada. I am 79 years old and a very athletic person most of my life. But my main issue is no stamina and always short of breath. I have been on a BTK blocker for 7 years to control my CLL. Chronic lymphocytic leukemia and
good morning, My name is Patrick McConnell and I live in Burlington Ontario Canada. I am 79 years old and a very athletic person most of my life. But my main issue is no stamina and always short of breath. I have been on a BTK blocker for 7 years to control my CLL. Chronic lymphocytic leukemia and
PRM54
in
AF Association
1 year ago
Difficulty turning over in bed
A few years ago l asked if any of you had trouble turning over in bed and got a lot of responses- some compared it to feeling like a beached whale ! Recently l had a shoulder replacement which made it even worse for me so my son came to my rescue. It has helped so much that l thought l would share it
A few years ago l asked if any of you had trouble turning over in bed and got a lot of responses- some compared it to feeling like a beached whale ! Recently l had a shoulder replacement which made it even worse for me so my son came to my rescue. It has helped so much that l thought l would share it
Trulyscrumpious
in
PMRGCAuk
1 year ago
Cancelled Again
Well here I go again, another cancellation, another wait. I have continual AF for just coming up to two years. I’m on 10mg of Bisoprolol and 62.5 digoxin, plus Apixaban. First appointment with Cardio, told to lose weight and get on with it, no medication, oh ok. Went to GP who gave medication and
Well here I go again, another cancellation, another wait. I have continual AF for just coming up to two years. I’m on 10mg of Bisoprolol and 62.5 digoxin, plus Apixaban. First appointment with Cardio, told to lose weight and get on with it, no medication, oh ok. Went to GP who gave medication and
Carnationmac
in
AF Association
1 year ago
A universal antiviral drug is being developed in Jerusalem
The next phase of ViroBlock’s
clinical
trials
will test the efficacy of its novel antiviral approach on humans. The company also has drugs in the pipeline currently being tested that could be effective against other viruses.
The next phase of ViroBlock’s
clinical
trials
will test the efficacy of its novel antiviral approach on humans. The company also has drugs in the pipeline currently being tested that could be effective against other viruses.
lupus-support1
Administrator
in
LUpus Patients Understanding and Support
2 years ago
Periodic episodes of fluctuating tachycardia while in AFib.
Never had any heart problems until early 2020. I'm a rather robust yet strong guy , late 40s. I suspect COVID may have had something to do with it. Never vaccinated either..went to e.r after having AFib for 16 hrs. Was blacking out at work. Thought I was going to die. Spent 2 days in hospital. Echocardiogram
Never had any heart problems until early 2020. I'm a rather robust yet strong guy , late 40s. I suspect COVID may have had something to do with it. Never vaccinated either..went to e.r after having AFib for 16 hrs. Was blacking out at work. Thought I was going to die. Spent 2 days in hospital. Echocardiogram
Arrythimicaneurysm
in
Arrhythmia Alliance
1 year ago
*TW*:Check in on depressed ppl who act happy out of nowhere. Im kinda preoccupied with my family but my friend attempting to end it, is uh
Shocking....I just. I just don't know what to say. I'm in a shock since yesterday. Remember i wrote about a friend on 1st of November? Then he dissapeared. Asked some common friend, she told me. But yesterday i was doing homework with her and he texted. I asked how he was, he said "i haven't told you
Shocking....I just. I just don't know what to say. I'm in a shock since yesterday. Remember i wrote about a friend on 1st of November? Then he dissapeared. Asked some common friend, she told me. But yesterday i was doing homework with her and he texted. I asked how he was, he said "i haven't told you
Against_the_current
in
Anxiety and Depression Support
1 year ago
Apixaban and Ablation
Hi everyone, I am currently on a very long waiting list for Ablation. I have PAF with very symptomatic episodes lasting 30 hours approximately every 4 months. I take apixaban and sotalol but do not want to up the dose as suggested by my EP (I currently take 40mg three times daily).At the last visit to
Hi everyone, I am currently on a very long waiting list for Ablation. I have PAF with very symptomatic episodes lasting 30 hours approximately every 4 months. I take apixaban and sotalol but do not want to up the dose as suggested by my EP (I currently take 40mg three times daily).At the last visit to
Karendeena
in
AF Association
1 year ago
Ketamine?
Levodopa, a standard Parkinson’s therapy, is a precursor molecule that is converted to dopamine in the brain. It is well-known for controlling Parkinson’s disease symptoms such as rigidity and slowness of movement. However, prolonged use of levodopa may result in spontaneous involuntary movements
Levodopa, a standard Parkinson’s therapy, is a precursor molecule that is converted to dopamine in the brain. It is well-known for controlling Parkinson’s disease symptoms such as rigidity and slowness of movement. However, prolonged use of levodopa may result in spontaneous involuntary movements
kaypeeoh
in
Cure Parkinson's
2 years ago
Mid-week Boost
Hi community! Wishing everyone a great Wednesday free of depression and anxiety. Reach out if you’re feeling down
Hi community! Wishing everyone a great Wednesday free of depression and anxiety. Reach out if you’re feeling down
Sawdust23
in
Anxiety and Depression Support
1 year ago
My Turn to Ask a Question
Hello all, For the last eight or nine years I have participated in this forum dispensing what little information I could to various participants. After nine years and four months on Zoladex (goserelin) and the last five years on Xtandi (enzalutamide) plus Zoladex my PSA has started to slowly climb.
Hello all, For the last eight or nine years I have participated in this forum dispensing what little information I could to various participants. After nine years and four months on Zoladex (goserelin) and the last five years on Xtandi (enzalutamide) plus Zoladex my PSA has started to slowly climb.
RyderLake2
in
Advanced Prostate Cancer
2 years ago
Advice please on raising prednisone
hi. Haven't been in touch for long while but I read here every day. Reminder I'm 74 yr old diagnosed march '22 with GCA started on 80 mg prednisone now down to 6 mg. Before I speak to rheumy wanted to be armed with good information. I'm facing kidney biopsy. Recovery in hospital 8 to 24 hours then 3
hi. Haven't been in touch for long while but I read here every day. Reminder I'm 74 yr old diagnosed march '22 with GCA started on 80 mg prednisone now down to 6 mg. Before I speak to rheumy wanted to be armed with good information. I'm facing kidney biopsy. Recovery in hospital 8 to 24 hours then 3
Cobalt2sister
in
PMRGCAuk
1 year ago
Autoimmune Registry
The Autoimmune Registry helps recruit patients like you for
clinical
research and
clinical
trials
. When a trial begins, we contact you to see if you can participate.
The Autoimmune Registry helps recruit patients like you for
clinical
research and
clinical
trials
. When a trial begins, we contact you to see if you can participate.
Rexz
in
Pernicious Anaemia Society
2 years ago
Digoxin fears
Hello,am new to this forum, at mo feeling I am in the minority taking digoxin really feeling anxious about having to take prob have read Mr Google far too much I had an episode of AF was taken into a&e tried to right it by high dose of bisoprolol but had no affect, after 20 hrs erratic beats 140 to
Hello,am new to this forum, at mo feeling I am in the minority taking digoxin really feeling anxious about having to take prob have read Mr Google far too much I had an episode of AF was taken into a&e tried to right it by high dose of bisoprolol but had no affect, after 20 hrs erratic beats 140 to
Ssuegos
in
AF Association
1 year ago
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