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Final STAMPEDE results for Abi with/out Enza when starting ADT.
New paper below [1]. "Between Nov 15, 2011, and Jan 17, 2014, 1003 patients were randomly assigned to standard of care (n=502) or standard of care plus abiraterone (n=501) in the abiraterone trial. "Between July 29, 2014, and March 31, 2016, 916 patients were randomly assigned to standard of care
New paper below [1]. "Between Nov 15, 2011, and Jan 17, 2014, 1003 patients were randomly assigned to standard of care (n=502) or standard of care plus abiraterone (n=501) in the abiraterone trial. "Between July 29, 2014, and March 31, 2016, 916 patients were randomly assigned to standard of care
pca2004
in
Fight Prostate Cancer
1 year ago
Phase II 2020-0200 Clinical Trial
Hello everyone, I was diagnosed in May 2021 at 50 years old. PSA 426/Gleason 8. Had been on Abiraterone Acetate (AA) along with Lupron and Prednisone. My PSA dropped to 0.1 until recently I became castrate resistant. I was advised by my team at MD Anderson that my cancer was a strong variant type.
Hello everyone, I was diagnosed in May 2021 at 50 years old. PSA 426/Gleason 8. Had been on Abiraterone Acetate (AA) along with Lupron and Prednisone. My PSA dropped to 0.1 until recently I became castrate resistant. I was advised by my team at MD Anderson that my cancer was a strong variant type.
Z06505hp
in
Advanced Prostate Cancer
1 year ago
PHASE 2 SATIVEX CLINICAL TRIAL (ARISTOCRAT)
Excellent news! The Brain Tumour Charity has announced that the Aristocrat Phase 2 clinical trial of SATIVEX is now going ahead. Please see the link below for further details. https://www.thebraintumourcharity.org/media-centre/news/research-news/aristocrat-a-pioneering-trial-using-a-cannabinoid-based-drug-to-treat-brain-tumours
Excellent news! The Brain Tumour Charity has announced that the Aristocrat Phase 2 clinical trial of SATIVEX is now going ahead. Please see the link below for further details. https://www.thebraintumourcharity.org/media-centre/news/research-news/aristocrat-a-pioneering-trial-using-a-cannabinoid-based-drug-to-treat-brain-tumours
Tansi75
in
Glioblastoma Support
1 year ago
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Patient Engagement Day UCL Cancer Trials Centre 23 June 2023
Hello All This is to let you know about a Patient Engagement Day being run by Cancer Research UK and UCL Cancer Trials Centre. The organisers have five patient spaces left available, and asked if any of our members would like to attend. It will be taking place in central London on Friday 23 June 2023
Hello All This is to let you know about a Patient Engagement Day being run by Cancer Research UK and UCL Cancer Trials Centre. The organisers have five patient spaces left available, and asked if any of our members would like to attend. It will be taking place in central London on Friday 23 June 2023
OvacomeSupport
My Ovacome Team
in
My Ovacome
1 year ago
Depression and anxiety
I'm having a hard go of this. This is my 4th Major Depressive Disorder over my life time. I always come out at the other end, but the feeling of being alone is awful.
I'm having a hard go of this. This is my 4th Major Depressive Disorder over my life time. I always come out at the other end, but the feeling of being alone is awful.
jleechis1
in
Anxiety and Depression Support
1 year ago
Life is so hard right now!
I am suffering from
clinical
depression
and it has been so hard! I’ve been here before. Wish I didn’t have this in my life!
I am suffering from
clinical
depression
and it has been so hard! I’ve been here before. Wish I didn’t have this in my life!
Ryleyboy
in
Anxiety and Depression Support
2 years ago
citalopram 20mg stopped working
was on 10mg to start, then 20mg for about 3 months was feeling great, noticed it starting to not have same effect then a trigger I got into low mood, doc recommended 30mg till the new year to see how I feel , have had some side effects lately not sleeping too well, and heightened anxiety has anyone had
was on 10mg to start, then 20mg for about 3 months was feeling great, noticed it starting to not have same effect then a trigger I got into low mood, doc recommended 30mg till the new year to see how I feel , have had some side effects lately not sleeping too well, and heightened anxiety has anyone had
macall75
in
Anxiety and Depression Support
1 year ago
The brain behind Buntanetap - Dr. Maria Maccecchini CEO of Annovis Bio
What you'll get out of this video: 📚 Dr. Maccecchini's background and how it led her to the founding of Annovis Bio? 🧪 How she transitioned from academia to biosciences 🩺 An overview of Annovis Bio’s approach and its lead compound? 📈 The data of the Buntanetap studies for Parkinson’s and Alzheimer
What you'll get out of this video: 📚 Dr. Maccecchini's background and how it led her to the founding of Annovis Bio? 🧪 How she transitioned from academia to biosciences 🩺 An overview of Annovis Bio’s approach and its lead compound? 📈 The data of the Buntanetap studies for Parkinson’s and Alzheimer
Farooqji
in
Cure Parkinson's
1 year ago
FDA Panel Rejects Broad Olaparib Indication in Metastatic CRPC — ODAC votes that olaparib-abiraterone comb be restricted to BRCA+ subset
Possible good news on the way for BRCA-mutated PCa patients. In this instance, it seems the ODAC actually read the results of the clinical trial and understood the efficacy (as indicated in the actual trial results) was limited to BRCA-mutated patients. * * * [i]
FDA Panel Rejects Broad Olaparib
Possible good news on the way for BRCA-mutated PCa patients. In this instance, it seems the ODAC actually read the results of the clinical trial and understood the efficacy (as indicated in the actual trial results) was limited to BRCA-mutated patients. * * * [i]
FDA Panel Rejects Broad Olaparib
cujoe
in
Fight Prostate Cancer
1 year ago
Residential treatment center and Prozac
Tuesday, I'm supposed to go to a residential treatment center. I started prozac two days ago. I've had chest pains since yesterday morning, so for today he lowered my dose. Still have them. Other side effects I have are more common; Anxiety, Emotional paralysis, like inertia, I just can't do anything
Tuesday, I'm supposed to go to a residential treatment center. I started prozac two days ago. I've had chest pains since yesterday morning, so for today he lowered my dose. Still have them. Other side effects I have are more common; Anxiety, Emotional paralysis, like inertia, I just can't do anything
Joshgw
in
Anxiety and Depression Support
1 year ago
Vitaman D and Prostate Cancer
Asian J Androl. 2018 May-Jun; 20(3): 244–252. Published online 2018 Apr 13. doi: 10.4103/aja.aja_14_18 PMCID: PMC5952478 PMID: 29667615 Vitamin D in prostate cancer Donald L Trump and Jeanny B Aragon-Ching Author information Article notes Copyright and License information Disclaimer Go to: Abstract
Asian J Androl. 2018 May-Jun; 20(3): 244–252. Published online 2018 Apr 13. doi: 10.4103/aja.aja_14_18 PMCID: PMC5952478 PMID: 29667615 Vitamin D in prostate cancer Donald L Trump and Jeanny B Aragon-Ching Author information Article notes Copyright and License information Disclaimer Go to: Abstract
Magnus1964
in
Advanced Prostate Cancer
1 year ago
Kidney Disease Clinical Trials: Are They Right for You?
Participating in a clinical trial could help you and future patients with CKD, but it is important to know possible risks and benefits involved. Learn more at: https://www.kidney.org/newsletter/kidney-disease-clinical-trials-are-they-right-you
Participating in a clinical trial could help you and future patients with CKD, but it is important to know possible risks and benefits involved. Learn more at: https://www.kidney.org/newsletter/kidney-disease-clinical-trials-are-they-right-you
JackieJ_NKF
Partner
in
Kidney Disease
1 year ago
Prozac and chest pains
Has anyone gotten chest pains as a side effect to taking prozac. I started it today and my chest is killing me. I've taken literally everything else, hospitalization, ECT, TMS and ketamine. It's my last hope. I need it to work. I've been very suicidal and bad Anxiety. Can anyone help please, I'm desperate
Has anyone gotten chest pains as a side effect to taking prozac. I started it today and my chest is killing me. I've taken literally everything else, hospitalization, ECT, TMS and ketamine. It's my last hope. I need it to work. I've been very suicidal and bad Anxiety. Can anyone help please, I'm desperate
Joshgw
in
Anxiety and Depression Support
1 year ago
I'd love to hear success stories about taking Buspirone for anxiety
I have had different degrees of anxiety my whole life. This has ranged from constant worry to full blown panic attacks for days on end. I was prescribed Celexa some years ago and didn't do well on it. I've tried to live my life the best I could while dealing with this disorder. Recently I had a major
I have had different degrees of anxiety my whole life. This has ranged from constant worry to full blown panic attacks for days on end. I was prescribed Celexa some years ago and didn't do well on it. I've tried to live my life the best I could while dealing with this disorder. Recently I had a major
jjf255
in
Anxiety Support
1 year ago
Cannot be bothered syndrome!
Hi, Having reduced my pred dose from 20mg, i have been on 7mg for 3 weeks. I had some initial tiredness and sugar craving. That seemed to improve but have been having some low mood and cannot be bothered syndrome and get around to it tomorrow. Is this a common symptom and does it pass? Thanks I
Hi, Having reduced my pred dose from 20mg, i have been on 7mg for 3 weeks. I had some initial tiredness and sugar craving. That seemed to improve but have been having some low mood and cannot be bothered syndrome and get around to it tomorrow. Is this a common symptom and does it pass? Thanks I
Animalover65
in
PMRGCAuk
1 year ago
Xeris subcutaneous levothyroxine
Slow at getting round to noticing this article and then posting about it! Given the numerous issues due to oral levothyroxine (whether solid or liquid), like tolerability, effects on gut, absorption, interference with food, drink, supplements and medicines, severe spiking of blood levels, and on and
Slow at getting round to noticing this article and then posting about it! Given the numerous issues due to oral levothyroxine (whether solid or liquid), like tolerability, effects on gut, absorption, interference with food, drink, supplements and medicines, severe spiking of blood levels, and on and
helvella
Thyroid UK
in
Thyroid UK
1 year ago
side affects of anxiety and depression meds
hello everyone this is my first post. I’m wondering if anyone has had negative side effects from taking Wellbutrin and serotonin medications. I started the serotonin in April and then the Wellbutrin mid May. In June my husband walked in the door and told him I wanted a divorce out of the blue. We went
hello everyone this is my first post. I’m wondering if anyone has had negative side effects from taking Wellbutrin and serotonin medications. I started the serotonin in April and then the Wellbutrin mid May. In June my husband walked in the door and told him I wanted a divorce out of the blue. We went
BlondeMomma88
in
Anxiety and Depression Support
1 year ago
ARE WE ALL "JUNKIES"
Yes. I was thinking about this really. Am I now a "Junkie". I guess so, but not by choice. Controlled drugs - yep I had to sign a form for pregabalin. I'm also on Nefopam too. An addict essentially but not by choice. Do I feel "normal" now. No I don't. I feel fogged actually. Do these two drugs KILL
Yes. I was thinking about this really. Am I now a "Junkie". I guess so, but not by choice. Controlled drugs - yep I had to sign a form for pregabalin. I'm also on Nefopam too. An addict essentially but not by choice. Do I feel "normal" now. No I don't. I feel fogged actually. Do these two drugs KILL
golly123
in
Fibromyalgia Action UK
1 year ago
Has anyone experienced benefits from coq10
According to the following article Comparing the youngest age people to the oldest, the number of striatal dopamine transporters was cut by 46%, or 6.6% per decade of life.3 The rate of loss of dopamine transporters is accelerated in Parkinson's patients, and this age-related factor may suggest why
According to the following article Comparing the youngest age people to the oldest, the number of striatal dopamine transporters was cut by 46%, or 6.6% per decade of life.3 The rate of loss of dopamine transporters is accelerated in Parkinson's patients, and this age-related factor may suggest why
Farooqji
in
Cure Parkinson's
1 year ago
Triplet Regimen vs Clinical Trial (Pluvicto)
I was recently diagnosed with advanced prostate cancer with diffuse bone metastases (March 20th). I met with my oncologist at Sloan Kettering on March 23rd and received my first hormone treatment (Degarelix). My PSA has already dropped from 189 to 23.89, and I had my second hormone treatment, which was
I was recently diagnosed with advanced prostate cancer with diffuse bone metastases (March 20th). I met with my oncologist at Sloan Kettering on March 23rd and received my first hormone treatment (Degarelix). My PSA has already dropped from 189 to 23.89, and I had my second hormone treatment, which was
Bruce98
in
Advanced Prostate Cancer
1 year ago
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