Search
Search
About
Log in
Join
Experiences with
Ceritinib
Posts
Communities
36 public posts
Filter results
Lorlatinib
So after 3 and half years
Ceritinib
has finally stopped working for me. It’s had a really good run but I always knew it wouldn’t be forever. I have been offered Lorlatinib as my next step in treatment.
So after 3 and half years
Ceritinib
has finally stopped working for me. It’s had a really good run but I always knew it wouldn’t be forever. I have been offered Lorlatinib as my next step in treatment.
BellaBe
in
The Roy Castle Lung Cancer Foundation
10 months ago
Caffeic acid phenethyl ester [CAPE]
New study [1]. "
Caffeic acid phenethyl ester suppresses EGFR/FAK/Akt signaling, migration, and tumor growth of prostate cancer cells
" There have been 2 dozen CAPE papers these last 20 years. Ten of these specifically mention Akt inhibition. CAPE is found in propolis, which bees use to seal
New study [1]. "
Caffeic acid phenethyl ester suppresses EGFR/FAK/Akt signaling, migration, and tumor growth of prostate cancer cells
" There have been 2 dozen CAPE papers these last 20 years. Ten of these specifically mention Akt inhibition. CAPE is found in propolis, which bees use to seal
pca2004
in
Fight Prostate Cancer
1 year ago
Radiation Necrosis?
I am stage 4 ALK positive and on treatment with
Ceritinib
for the last 3 years and was diagnosed over 5 years ago. I had SRS to 4 brain mets about 13 months ago. They responded really well with 2 disappearing,1 shrinking and one stable.
I am stage 4 ALK positive and on treatment with
Ceritinib
for the last 3 years and was diagnosed over 5 years ago. I had SRS to 4 brain mets about 13 months ago. They responded really well with 2 disappearing,1 shrinking and one stable.
BellaBe
in
The Roy Castle Lung Cancer Foundation
2 years ago
Want to take advantage of all our features? Just log in!
Log in
or
Join
Growth inhibitory effect of doxazosin on prostate and bladder cancer cells. Is the serotonin receptor pathway involved?
Doxazosin
, an alpha1-adrenoceptor antagonist, is used for the treatment of benign prostatic hyperplasia (BPH) and hypertension. Alpha-adrenoceptor antagonists also inhibit growth and induce apoptosis in malignant prostatic cells. The apoptotic activity is independent of their capacity to antagonize
Doxazosin
, an alpha1-adrenoceptor antagonist, is used for the treatment of benign prostatic hyperplasia (BPH) and hypertension. Alpha-adrenoceptor antagonists also inhibit growth and induce apoptosis in malignant prostatic cells. The apoptotic activity is independent of their capacity to antagonize
Hidden
in
Advanced Prostate Cancer
2 years ago
Dose reduction, advice please?
Hello I was just wondering if anyone has had a dose reduction from
Ceritinib
? I have been taking it successfully for 2 and a half years on the full dose of 450mg but have always struggled with gastric side effects.
Hello I was just wondering if anyone has had a dose reduction from
Ceritinib
? I have been taking it successfully for 2 and a half years on the full dose of 450mg but have always struggled with gastric side effects.
BellaBe
in
The Roy Castle Lung Cancer Foundation
3 years ago
Brain Mets
My lung cancer is well controlled with targeted therapy,
Ceritinib
but they have just found 3 small tumours in my brain. I’m really frightened as I have read that the average survival with brain mets is 6 months. I’m only 47. Any experience with this would be much appreciated. Thanks x
My lung cancer is well controlled with targeted therapy,
Ceritinib
but they have just found 3 small tumours in my brain. I’m really frightened as I have read that the average survival with brain mets is 6 months. I’m only 47. Any experience with this would be much appreciated. Thanks x
BellaBe
in
The Roy Castle Lung Cancer Foundation
3 years ago
Not sure if I should be worried?
I am stage 4 ALK+ and have been on
Ceritinib
for 2 years now which is working well. I have CT scans every 3 months to keep an eye on things and have always been told that my lungs are clear from tumours.
I am stage 4 ALK+ and have been on
Ceritinib
for 2 years now which is working well. I have CT scans every 3 months to keep an eye on things and have always been told that my lungs are clear from tumours.
BellaBe
in
The Roy Castle Lung Cancer Foundation
4 years ago
On gefitinib
My wife has been on gefitinib for 3 years now for sclc doing fairly well a lot of side effects I just wanted to know if anybody was in the same drug did they weakness in the legs and coordination problems would appreciate some feedback thank you
My wife has been on gefitinib for 3 years now for sclc doing fairly well a lot of side effects I just wanted to know if anybody was in the same drug did they weakness in the legs and coordination problems would appreciate some feedback thank you
Miceal58
in
The Roy Castle Lung Cancer Foundation
4 years ago
Ceritinib hard capsule discontinued
I just wondered if there is anyone else out there who are now having to take
Ceritinib
as a film coated tablet? The capsule has been discontinued and initially I was very pleased as the tablet is much smaller than the capsule.
I just wondered if there is anyone else out there who are now having to take
Ceritinib
as a film coated tablet? The capsule has been discontinued and initially I was very pleased as the tablet is much smaller than the capsule.
BellaBe
in
The Roy Castle Lung Cancer Foundation
4 years ago
High risk category? Letter received?
I am on targeted therapy
Ceritinib
which as far as I was aware is one of the protein kinase inhibitors which is on the government’s high risk list. I have had no text or letter advising me to stay home for 12 weeks and am worried that I have slipped through the net somehow.
I am on targeted therapy
Ceritinib
which as far as I was aware is one of the protein kinase inhibitors which is on the government’s high risk list. I have had no text or letter advising me to stay home for 12 weeks and am worried that I have slipped through the net somehow.
BellaBe
in
The Roy Castle Lung Cancer Foundation
4 years ago
Drug Submission time again. We are looking to speak to anyone who has experience of Loratinib (Lorviqua)
The indication this new medicine will be assessed under is: "As monotherapy is indicated for the treatment of adult patients with anaplastic lymphoma kinase (ALK) positive advanced non-small cell lung cancer (NSCLC) whose disease has progressed after: Alectinib or
ceritinib
as the first ALK tyrosine
The indication this new medicine will be assessed under is: "As monotherapy is indicated for the treatment of adult patients with anaplastic lymphoma kinase (ALK) positive advanced non-small cell lung cancer (NSCLC) whose disease has progressed after: Alectinib or
ceritinib
as the first ALK tyrosine
NicF4
Administrator
in
The Roy Castle Lung Cancer Foundation
5 years ago
Others like me
I was diagnosed with stage 4 lung cancer, metastasised on Xmas day last year and had no symptoms until I got breathless on Dec 16th. I'm 63. I've never smoked or drunk alcohol. I need oxygen regularly through the day. I have felt so isolated and angry since. I have not met anyone in my position at the
I was diagnosed with stage 4 lung cancer, metastasised on Xmas day last year and had no symptoms until I got breathless on Dec 16th. I'm 63. I've never smoked or drunk alcohol. I need oxygen regularly through the day. I have felt so isolated and angry since. I have not met anyone in my position at the
Terrierbob
in
The Roy Castle Lung Cancer Foundation
5 years ago
Targeted therapy working beyond expectations
I am currently taking
Ceritinib
for stage 4 ALK positive lung cancer,my first 3 month scan showed a big reduction in size and quantity of tumours. My recent 6 month scan shows I have had a complete pathological response to the drug, which makes the dodgy side effects all worth it.
I am currently taking
Ceritinib
for stage 4 ALK positive lung cancer,my first 3 month scan showed a big reduction in size and quantity of tumours. My recent 6 month scan shows I have had a complete pathological response to the drug, which makes the dodgy side effects all worth it.
BellaBe
in
The Roy Castle Lung Cancer Foundation
5 years ago
Ceritinib Query
Hi everyone, I’m currently on the 450 mg dose of
Ceritinib
with food and have been for the last 4 months. I take mine in the morning but do suffer with stomach cramps, diarrhoea and nausea for several hours after.
Hi everyone, I’m currently on the 450 mg dose of
Ceritinib
with food and have been for the last 4 months. I take mine in the morning but do suffer with stomach cramps, diarrhoea and nausea for several hours after.
BellaBe
in
The Roy Castle Lung Cancer Foundation
5 years ago
Integrating Novel Targets and Precision Medicine Into Prostate Cancer Care—Part 1: The Non-Androgen–Targetable Pathways in Castration-Resist
Good article that provides an update - LOTS going on!! Integrating Novel Targets and Precision Medicine Into Prostate Cancer Care—Part 1: The Non-Androgen–Targetable Pathways in Castration-Resistant Prostate Cancer Bryden Considine, DODaniel P. Petrylak, MD March 13, 2019 Volume: 33Issue: 3 Prostate
Good article that provides an update - LOTS going on!! Integrating Novel Targets and Precision Medicine Into Prostate Cancer Care—Part 1: The Non-Androgen–Targetable Pathways in Castration-Resistant Prostate Cancer Bryden Considine, DODaniel P. Petrylak, MD March 13, 2019 Volume: 33Issue: 3 Prostate
JLS1
in
Advanced Prostate Cancer
5 years ago
“Disease Flare” in lung cancer
Hi all 😊 I am still around and check in on you all even if I don’t always post. As a lot of you know, my dad had stage IV NSCLC adenocarcinoma diagnosed 2/28/18, low tumor volume, and was held stable until 9/2018 at which time he went into the hospital on 10/16 and heartbreakingly passed on 11/20/18
Hi all 😊 I am still around and check in on you all even if I don’t always post. As a lot of you know, my dad had stage IV NSCLC adenocarcinoma diagnosed 2/28/18, low tumor volume, and was held stable until 9/2018 at which time he went into the hospital on 10/16 and heartbreakingly passed on 11/20/18
Lisam81
in
Lung Cancer Support
5 years ago
Trying to be hopeful
Apparently my cancer has the ALK mutation so I am being prescribed
Ceritinib
, with a view to buying me more time with my family. I was advised this could amount to a number of years. Does anyone have any experience of taking this drug?
Apparently my cancer has the ALK mutation so I am being prescribed
Ceritinib
, with a view to buying me more time with my family. I was advised this could amount to a number of years. Does anyone have any experience of taking this drug?
BellaBe
in
The Roy Castle Lung Cancer Foundation
6 years ago
Advice on drug
My wife is on gefitinib doing fairly well cancer stable but she has very bad itching in her arms any advice has used e45 not helping
My wife is on gefitinib doing fairly well cancer stable but she has very bad itching in her arms any advice has used e45 not helping
Miceal58
in
The Roy Castle Lung Cancer Foundation
6 years ago
Pemetrexed seems not to work
Ceritinib
was amazingly successful but pneumonitis meant we had to stop for now. Carb and Pem with 3 cycles of Pem but new brain secondaries. CT body today and Gamma Knife again as mets are symptomatic.
Ceritinib
was amazingly successful but pneumonitis meant we had to stop for now. Carb and Pem with 3 cycles of Pem but new brain secondaries. CT body today and Gamma Knife again as mets are symptomatic.
Stouens
in
The Roy Castle Lung Cancer Foundation
6 years ago
SD last CXR
Diagnosed S4 with brain secondaries Feb 18 treated with Gamma Knife and
ceritinib
. Pneumonia so now just going onto Pem maintenance. Initial partial response now SD. ROS 1
Diagnosed S4 with brain secondaries Feb 18 treated with Gamma Knife and
ceritinib
. Pneumonia so now just going onto Pem maintenance. Initial partial response now SD. ROS 1
Stouens
in
The Roy Castle Lung Cancer Foundation
6 years ago
1
2
Next page
Filter results
Clear filters
Posted in
All communities
The Roy Castle Lung Cancer Foundation
29 results
Advanced Prostate Cancer
5 results
Fight Prostate Cancer
1 result
View top 10 communities
Sort by
Most Relevant
Newest