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Castration
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What is mCRPC
I’m getting mixed signals on whether or not my cancer is
castration
resistant. My PSA went down to zero after chemo but has risen to 20 over the past year while on Lupron. My oncologist said that since my bone mets have not returned I am not
castration
resistant.
I’m getting mixed signals on whether or not my cancer is
castration
resistant. My PSA went down to zero after chemo but has risen to 20 over the past year while on Lupron. My oncologist said that since my bone mets have not returned I am not
castration
resistant.
ewhite999
in
Advanced Prostate Cancer
6 years ago
From a Post I was going to put on Facebook, but didn't.
it's
CASTRATION
. 4. RE. 3 (above)....one of the main side effect of
CASTRATION
is depression.
it's
CASTRATION
. 4. RE. 3 (above)....one of the main side effect of
CASTRATION
is depression.
greatjohn
in
Advanced Prostate Cancer
6 years ago
Castration resistant prostate cancer - Starting Jevtana with Prednisone in a few days
My Dad has
castration
resistant prostate cancer. He has already done surgery over 20 years ago, and has tried Zytiga for about two years until it stopped working. He was placed on Xtandi which put his body through hell. His doctor had to stop the medication and gave my Dad a few months to recover.
My Dad has
castration
resistant prostate cancer. He has already done surgery over 20 years ago, and has tried Zytiga for about two years until it stopped working. He was placed on Xtandi which put his body through hell. His doctor had to stop the medication and gave my Dad a few months to recover.
afhhr
in
Advanced Prostate Cancer
6 years ago
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Erleada , a new prostate cancer treatment
Erleada just received FDA approval for non-metastatic
castration
resistent prostate cancer. https://malecare.org/erleada/ Ever though many in this community may not be in the nmCRPC category, I think we can all feel hopeful that new treatments are being developed.
Erleada just received FDA approval for non-metastatic
castration
resistent prostate cancer. https://malecare.org/erleada/ Ever though many in this community may not be in the nmCRPC category, I think we can all feel hopeful that new treatments are being developed.
Darryl
Partner
in
Prostate Cancer Network
6 years ago
Good news for those with nonmetastatic castration resistant prostate cancer
It was just announced that the FDA has approved the first drug aimed exclusively for those warriors here who’s cancer has not spread but where it has become
castration
resistant.
It was just announced that the FDA has approved the first drug aimed exclusively for those warriors here who’s cancer has not spread but where it has become
castration
resistant.
Dr_WHO
in
Advanced Prostate Cancer
6 years ago
EAU18 Copenhagen. BRCA Testing.
"EAU 2018: Case-Based Debate: BRCA 1/2 Testing Before Treatment of Metastatic
Castration
-Resistant Prostate Cancer - Ready for Prime Time Copenhagen, Denmark (UroToday.com) Dr.
"EAU 2018: Case-Based Debate: BRCA 1/2 Testing Before Treatment of Metastatic
Castration
-Resistant Prostate Cancer - Ready for Prime Time Copenhagen, Denmark (UroToday.com) Dr.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Cross-resistance between Ethinylestradiol and Enzalutamide
KEYWORDS:
castration
-resistant prostate cancer; docetaxel; enzalutamide; ethinylestradiol PMID: 29521011 DOI: 10.1111/iju.13542
KEYWORDS:
castration
-resistant prostate cancer; docetaxel; enzalutamide; ethinylestradiol PMID: 29521011 DOI: 10.1111/iju.13542
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Transfusion dependent after Radium 223 and Xtandi - DRs want to stop his weekly transfusions. Help!
My dad has
castration
resistant advanced prostate cancer with bone metastasis and suddenly became transfusion dependent on a weekly basis just one month ago. He had been getting monthly Radium 223 injections for 3-4 months and taking Xtandi.
My dad has
castration
resistant advanced prostate cancer with bone metastasis and suddenly became transfusion dependent on a weekly basis just one month ago. He had been getting monthly Radium 223 injections for 3-4 months and taking Xtandi.
Ellehaze
in
Advanced Prostate Cancer
6 years ago
Fewer drugs after surgical castration? Upside? Downside?
Is Orchiectomy a durable cure? Does one continue on some form of ADT or wait until a rise in Testosterone and PSA? I admit my ignorance, so please be kind (thinking of Nala...et.al).
Is Orchiectomy a durable cure? Does one continue on some form of ADT or wait until a rise in Testosterone and PSA? I admit my ignorance, so please be kind (thinking of Nala...et.al).
ronton2
in
Advanced Prostate Cancer
6 years ago
Is Orchidectomy right for me?
I am considering surgical
castration
as an option to chemical treatment for PCa. I have been taking Lupron/Zytiga + prednisone for nearly a year. The results have been excellent--PSA undetectable--and I have grown used to the side effects, which, in my case, have not been unendurable.
I am considering surgical
castration
as an option to chemical treatment for PCa. I have been taking Lupron/Zytiga + prednisone for nearly a year. The results have been excellent--PSA undetectable--and I have grown used to the side effects, which, in my case, have not been unendurable.
ronton2
in
Advanced Prostate Cancer
6 years ago
Castration resistant prostate cancer
Hello, I have metastatic prostate cancer (bony metastases). Thus far, I have had 39 radiation treatments, have been on Lupron for over one year (in tandem with Bicumulide first, and now Xtandi). Due to a recent increase in my PSA, I will soon begin Provenge treatment. I have no pain and have, from the
Hello, I have metastatic prostate cancer (bony metastases). Thus far, I have had 39 radiation treatments, have been on Lupron for over one year (in tandem with Bicumulide first, and now Xtandi). Due to a recent increase in my PSA, I will soon begin Provenge treatment. I have no pain and have, from the
N-Kitch
in
Advanced Prostate Cancer
6 years ago
ADT or Orchiectomy
Four months back the disease turned to
castration
resistant. My M.O has added zytiga. But I have to still continue Lupron injections. I am looking for the possibility of an Orchiectomy as an alternative for lupron injections to reduce my expenses. Is it a good decision?
Four months back the disease turned to
castration
resistant. My M.O has added zytiga. But I have to still continue Lupron injections. I am looking for the possibility of an Orchiectomy as an alternative for lupron injections to reduce my expenses. Is it a good decision?
dress2544
in
Advanced Prostate Cancer
6 years ago
Immunotherapy for Prostate Cancer: Where Do We Go From Here?—PART 1: Prostate Cancer Vaccines
prostate cancer (NCT02649855), and
castration
-resistant prostate cancer (NCT01867333, NCT02933255) settings.
prostate cancer (NCT02649855), and
castration
-resistant prostate cancer (NCT01867333, NCT02933255) settings.
JLS1
in
Advanced Prostate Cancer
6 years ago
Phase II Study of Low-Dose Abiraterone With Food.
[Epub ahead of print] Prospective International Randomized Phase II Study of Low-Dose Abiraterone With Food Versus Standard Dose Abiraterone In
Castration
-Resistant Prostate Cancer.
[Epub ahead of print] Prospective International Randomized Phase II Study of Low-Dose Abiraterone With Food Versus Standard Dose Abiraterone In
Castration
-Resistant Prostate Cancer.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Damned if you do/Damned if you don't....Old Expression with NEW meaning.
P.P.S. when I was describing the "joys of Lupron/
Castration
" to my chiropractor...he asked...but "how long do you have to do it?" ~~OY, when I said...not sure...but "as long as I live" is what it seems like...even he looked SAD ! ! !
P.P.S. when I was describing the "joys of Lupron/
Castration
" to my chiropractor...he asked...but "how long do you have to do it?" ~~OY, when I said...not sure...but "as long as I live" is what it seems like...even he looked SAD ! ! !
greatjohn
in
Advanced Prostate Cancer
6 years ago
ASCO Issues New Guidelines for Optimizing Anticancer Therapy in Metastatic non-CRPC.
. - The appropriate regimen of abiraterone is 1,000 mg with either prednisolone or prednisone 5 mg once daily until treatment(s) for metastatic
castration
-resistant disease are initiated. - The panel noted that ADT plus docetaxel vs ADT plus abiraterone have not been compared, and it is unknown if some
. - The appropriate regimen of abiraterone is 1,000 mg with either prednisolone or prednisone 5 mg once daily until treatment(s) for metastatic
castration
-resistant disease are initiated. - The panel noted that ADT plus docetaxel vs ADT plus abiraterone have not been compared, and it is unknown if some
pjoshea13
in
Advanced Prostate Cancer
6 years ago
A "Novel" CRPC Mechanism.
Persistence of intratumoral androgens has been found in
castration
-resistant prostate cancer and attributed to increased in situ synthesis. Recently, Sharifi and colleagues reported an additional mechanism that can enhance local androgenic exposure: downregulation of an androgen-inactivating enzyme.
Persistence of intratumoral androgens has been found in
castration
-resistant prostate cancer and attributed to increased in situ synthesis. Recently, Sharifi and colleagues reported an additional mechanism that can enhance local androgenic exposure: downregulation of an androgen-inactivating enzyme.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
ASCO Genitourinary Cancers Symposium (Statin use & outcomes.)
{prednisone (P), abiraterone (AA)} -Patrick 230 Poster Session (Board #L6), Thu, 11:30 AM-1:00 PM and 5:15 PM-6:15 PM Impact of statins on outcomes in patients (pts) with metastatic
castration
resistant prostate cancer (mCRPC): Post-hoc analysis of data from COU-AA-301 and COU-AA-302 trials.
{prednisone (P), abiraterone (AA)} -Patrick 230 Poster Session (Board #L6), Thu, 11:30 AM-1:00 PM and 5:15 PM-6:15 PM Impact of statins on outcomes in patients (pts) with metastatic
castration
resistant prostate cancer (mCRPC): Post-hoc analysis of data from COU-AA-301 and COU-AA-302 trials.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
ASCO Genitourinary Cancers Symposium (Statins again)
-Patrick 277 Poster Session (Board #N9), Thu, 11:30 AM-1:00 PM and 5:15 PM-6:15 PM Statin use and outcomes of patients (pts) with metastatic
castration
resistant prostate cancer (mCRPC) being treated with abiraterone (Abi). Jacob A Gordon, Bernhard J. Eigl, Jennifer A.
-Patrick 277 Poster Session (Board #N9), Thu, 11:30 AM-1:00 PM and 5:15 PM-6:15 PM Statin use and outcomes of patients (pts) with metastatic
castration
resistant prostate cancer (mCRPC) being treated with abiraterone (Abi). Jacob A Gordon, Bernhard J. Eigl, Jennifer A.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
Ralaniten [EPI-506]
Unfortunately, the clinical trial "Safety and Anti-Tumor Study of Oral EPI-506 for Patients With Metastatic
Castration
-Resistant Prostate Cancer" has been terminated: "At end of Phase 1 excessive high pill burden (18 capsules/day)" [3] 18 caps? Why, that's nothing to Nalakrats.
Unfortunately, the clinical trial "Safety and Anti-Tumor Study of Oral EPI-506 for Patients With Metastatic
Castration
-Resistant Prostate Cancer" has been terminated: "At end of Phase 1 excessive high pill burden (18 capsules/day)" [3] 18 caps? Why, that's nothing to Nalakrats.
pjoshea13
in
Advanced Prostate Cancer
6 years ago
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