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Carbidopa / Levodopa
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12 months
A year ago yesterday I officially retired to become a professional caregiver. Not sure how professional I am but we’re supposed to say that so as not to feel invisible. This is explained in a book that someone mentioned on this site titled “The Selfish Pig’s Guide To Caring”. I’ve only read a few chapters
A year ago yesterday I officially retired to become a professional caregiver. Not sure how professional I am but we’re supposed to say that so as not to feel invisible. This is explained in a book that someone mentioned on this site titled “The Selfish Pig’s Guide To Caring”. I’ve only read a few chapters
SewBears
in
PSP Association
5 years ago
L-carnosine
It seems like L-carnosine, a natural molecule of the brain, may have some significant benefits for PWP: https://www.mdpi.com/2072-6643/10/2/147 https://www.ncbi.nlm.nih.gov/pubmed/18729814 Following is the relevant quotation from self hacked.com: 10) May Treat Parkinson’s Disease Carnosine reduces
It seems like L-carnosine, a natural molecule of the brain, may have some significant benefits for PWP: https://www.mdpi.com/2072-6643/10/2/147 https://www.ncbi.nlm.nih.gov/pubmed/18729814 Following is the relevant quotation from self hacked.com: 10) May Treat Parkinson’s Disease Carnosine reduces
MehmetKutlu
in
Cure Parkinson's
5 years ago
Awful lot of levodopa for such a short disease duration
Anyone on 6 x
Carbidopa
Levodopa
25/100 mg, less than 2 years after diagnosis? My neuro is increasing my c/l from 1 tablet 3 x a day to 2 tablets 3 x a day. It seems to me like it's an awful lot of levodopa for such a short disease duration.
Anyone on 6 x
Carbidopa
Levodopa
25/100 mg, less than 2 years after diagnosis? My neuro is increasing my c/l from 1 tablet 3 x a day to 2 tablets 3 x a day. It seems to me like it's an awful lot of levodopa for such a short disease duration.
Parkie-
in
Cure Parkinson's
5 years ago
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Why should not we increase L-Dopa bioavailability in the Brain
After watching this video you will find out why you shouldn’t manipulate the L Dopa bioavailability in the brain. https://youtu.be/_eq28PCvfsg You are trying to balance something but you will end up messing with the same thing, in this case the Dopamine.
After watching this video you will find out why you shouldn’t manipulate the L Dopa bioavailability in the brain. https://youtu.be/_eq28PCvfsg You are trying to balance something but you will end up messing with the same thing, in this case the Dopamine.
Kia17
in
Cure Parkinson's
5 years ago
Generic Treatment for Parkinson Disease Receives FDA Approval
Alembic Pharmaceuticals has received FDA approval for its
Carbidopa
and
Levodopa
Extended-Release Tablets USP, 2.5 mg/100 mg and 50 mg/200 mg, according to the company.
Alembic Pharmaceuticals has received FDA approval for its
Carbidopa
and
Levodopa
Extended-Release Tablets USP, 2.5 mg/100 mg and 50 mg/200 mg, according to the company.
Farooqji
in
Cure Parkinson's
5 years ago
Can you take sinemet and sertraline (Zoloft) together ?
Can you take them together or do they need to be spaced out. Hubby has been leaving a gap between sinemet and breakfast with his sertraline and vitamins but I’m wondering if he can take the sertraline at the same time as the sinemet to get it into him earlier in the morning. He is struggling with the
Can you take them together or do they need to be spaced out. Hubby has been leaving a gap between sinemet and breakfast with his sertraline and vitamins but I’m wondering if he can take the sertraline at the same time as the sinemet to get it into him earlier in the morning. He is struggling with the
LAJ12345
in
Cure Parkinson's
5 years ago
Scratching your head for the origin of Parkinsons - is there a common link between Dandruff and PD ?
This Canadian-Spanish team examines the hypothesis that the micro-fungus, Malassezzia which causes dandruff and seborrheic dermatitis (SD) xould get into the brain and damage cells. The association between the two conditions may also be due to a common factor that helps promote both conditions. Not
This Canadian-Spanish team examines the hypothesis that the micro-fungus, Malassezzia which causes dandruff and seborrheic dermatitis (SD) xould get into the brain and damage cells. The association between the two conditions may also be due to a common factor that helps promote both conditions. Not
wriga
in
Cure Parkinson's
5 years ago
APL-130277 still without FDA Approval: Why?
Apomorphine is a somewhat strange Dopamine Agonist (non-egoline DA Parky B!) that required subcutaneous injections. It certainly hasn't been a mainline DA prescription in the USA. Sunovian developed back in 2012 a 2 part sublingual film that was applied under the tongue to reduce the difficulties of
Apomorphine is a somewhat strange Dopamine Agonist (non-egoline DA Parky B!) that required subcutaneous injections. It certainly hasn't been a mainline DA prescription in the USA. Sunovian developed back in 2012 a 2 part sublingual film that was applied under the tongue to reduce the difficulties of
sharoncrayn
in
Cure Parkinson's
5 years ago
Levodopa and CYP3A4, but probably not Grapefruit juice... The next steps
The next step in my research will be to help set up a "Proof of Concept" trial, hopefully with an international team of experts in pharmacology, pharmacokinetics, drug development and Parkinson's disease. This means scientifically answering the following question (or something like it). "Does inhibition
The next step in my research will be to help set up a "Proof of Concept" trial, hopefully with an international team of experts in pharmacology, pharmacokinetics, drug development and Parkinson's disease. This means scientifically answering the following question (or something like it). "Does inhibition
wriga
in
Cure Parkinson's
5 years ago
Does Magnesium, especially L-Threonate cancels out levadopa effect?
Hi, My PD friend has leg / foot cramp and I suggested Magnesium, but she said it cancels out levodopa (c/l). Any suggestion please? Thanks.
Hi, My PD friend has leg / foot cramp and I suggested Magnesium, but she said it cancels out levodopa (c/l). Any suggestion please? Thanks.
TL500
in
Cure Parkinson's
5 years ago
Please spell it out for me.
I currently take 2 tablets of generic for Sinemet 25mg
carbidopa
100mg
levodopa
4 times per day at about 6 a.m., noon, 6 p.m. and midnight or when I wake during the night. I am also doing the HCL thiamine and after much experimentation settled on 1 500mg capsule in the a.m.
I currently take 2 tablets of generic for Sinemet 25mg
carbidopa
100mg
levodopa
4 times per day at about 6 a.m., noon, 6 p.m. and midnight or when I wake during the night. I am also doing the HCL thiamine and after much experimentation settled on 1 500mg capsule in the a.m.
ladyaudree
in
Cure Parkinson's
5 years ago
Apomorphin and L Dopa, both s.c.
Has anybody tested this new therapeutic option? In Autria as apoorphinr and D-mine are available.
Has anybody tested this new therapeutic option? In Autria as apoorphinr and D-mine are available.
matthias_baum
in
Cure Parkinson's
5 years ago
Chronic nausea anyone?
Does anyone experience "chronic" nausea on their
carbidopa
/
levodopa
...my brother has been on meds for 5 years now....and has had chronic nausea for about 3-4 years. It's terrible.
Does anyone experience "chronic" nausea on their
carbidopa
/
levodopa
...my brother has been on meds for 5 years now....and has had chronic nausea for about 3-4 years. It's terrible.
Brills3
in
Cure Parkinson's
5 years ago
Homocysteine: friend or foe?
Those who are canny will recognize that homocysteine levels can be elevated by taking levodopa, and this may lead to unwanted health side effects. (There are things you can do to mitigate this.) However, does mean that homocysteine is just bad? Maybe not. Have a peek the interconnected Methylation
Those who are canny will recognize that homocysteine levels can be elevated by taking levodopa, and this may lead to unwanted health side effects. (There are things you can do to mitigate this.) However, does mean that homocysteine is just bad? Maybe not. Have a peek the interconnected Methylation
ElliotGreen
in
Cure Parkinson's
5 years ago
C/L CR with food?
Many places it is written to avoid taking C/L with food. I think this to avoid the C/L absorption problems when the meal contain protein, and also, I guess if you take the C/L immediately after a large meal, it could be a while before the C/L reaches the small colon (where it can be absorbed)... But
Many places it is written to avoid taking C/L with food. I think this to avoid the C/L absorption problems when the meal contain protein, and also, I guess if you take the C/L immediately after a large meal, it could be a while before the C/L reaches the small colon (where it can be absorbed)... But
Hidden
in
Cure Parkinson's
5 years ago
Cause of dyskinesia? Parkinsons or carbilev? Advice about amantadine?
I am on half 100/25 c/l more or less every 6 hours. I am fine during the day but I have to get up and move during the night or I end up jerking hopelessly for hours. Last night I was up from 12 to 1.30 and again at 4 am. When I told the neuro that I feel cl does nothing for me (my tremor gets worse
I am on half 100/25 c/l more or less every 6 hours. I am fine during the day but I have to get up and move during the night or I end up jerking hopelessly for hours. Last night I was up from 12 to 1.30 and again at 4 am. When I told the neuro that I feel cl does nothing for me (my tremor gets worse
Celtis
in
Cure Parkinson's
5 years ago
Wallowing in the Trough of Carbidopa and Benserazide
I hesitate to even start a thread that is heresy to many, many PD sufferers, many self proclaimed pharmacologists/biochemists on this forum and many of their physicians as well. It is all about a couple of PD drugs that can go very deadly if used inappropriately. Please realize, if you can do so, that
I hesitate to even start a thread that is heresy to many, many PD sufferers, many self proclaimed pharmacologists/biochemists on this forum and many of their physicians as well. It is all about a couple of PD drugs that can go very deadly if used inappropriately. Please realize, if you can do so, that
sharoncrayn
in
Cure Parkinson's
5 years ago
Barlowe's herbals elixirs Macuna Pruriens
Seed extract 650mg. 40% PILL form it's white, I thought I was getting the whole herb which is brown, this looks like it's pure L-dopa. Has anyone tried this, and how much would replace 25/100 cardopa/levadopa. I take 2 25/100 every 3 half hours. I would like to try cutting back one pill and replace
Seed extract 650mg. 40% PILL form it's white, I thought I was getting the whole herb which is brown, this looks like it's pure L-dopa. Has anyone tried this, and how much would replace 25/100 cardopa/levadopa. I take 2 25/100 every 3 half hours. I would like to try cutting back one pill and replace
akgirlsrock
in
Cure Parkinson's
5 years ago
Dyskinesia control
Hello! Could you please give ideas how to control dyskinesia from long term levodopa usage?
Hello! Could you please give ideas how to control dyskinesia from long term levodopa usage?
GalinaBlanca
in
Cure Parkinson's
5 years ago
PD Without Rigidity.
Are there any PWP here that don't have rigidity? I don't mean body stiffness but mean no trouble with handwriting, no cogwheel rigidity in any joints? I have stiff neck 24/7 and axial (central body) stiffness that affects walking making me slow and off balance but no rigidity as yet. L-Dopa relieves
Are there any PWP here that don't have rigidity? I don't mean body stiffness but mean no trouble with handwriting, no cogwheel rigidity in any joints? I have stiff neck 24/7 and axial (central body) stiffness that affects walking making me slow and off balance but no rigidity as yet. L-Dopa relieves
rideabike
in
Cure Parkinson's
5 years ago
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