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Experiences with
Calquence
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Calquence headache question
My wife has just
Calquence
and has”waves” of light headaches in the front part of brain. Her question to others taking
calquence
is the front headache area the common place for headache?
My wife has just
Calquence
and has”waves” of light headaches in the front part of brain. Her question to others taking
calquence
is the front headache area the common place for headache?
GL64
in
CLL Support
5 years ago
What do you do when you are MRD Negative?
We had been planning on adding
calquence
. My doctor still wants to do that. It seems he wants to hit it hard while it is down. On the other hand, I'd like to relax and save the meds for later. So, perhaps just stay on a reduced dosage of venetoclax.
We had been planning on adding
calquence
. My doctor still wants to do that. It seems he wants to hit it hard while it is down. On the other hand, I'd like to relax and save the meds for later. So, perhaps just stay on a reduced dosage of venetoclax.
profrich
in
CLL Support
5 years ago
acalabrutinib gets Breakthrough Therapy Designation for CLL from FDA
https://www.astrazeneca.com/media-centre/press-releases/2019/
calquence
-granted-us-breakthrough-therapy-designation-for-chronic-lymphocytic-leukaemia-14082019.html Hopefully FDA approval will follow within a few months. When V+O got the BTD in March 2019, it was approved in May 2019.
https://www.astrazeneca.com/media-centre/press-releases/2019/
calquence
-granted-us-breakthrough-therapy-designation-for-chronic-lymphocytic-leukaemia-14082019.html Hopefully FDA approval will follow within a few months. When V+O got the BTD in March 2019, it was approved in May 2019.
avzuclav
in
CLL Support
5 years ago
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Factors Identified for Risk of Second Cancer in CLL Following BTK Inhibition
The study analyzed 691 patients with CLL who were treated with either acalabrutinib (
Calquence
) or ibrutinib (Imbruvica) and developed a second primary malignancy.
The rate of developing a second primary neoplasia in patients with CLL treated with this class of agents was 7.6% at 3 years
.
The study analyzed 691 patients with CLL who were treated with either acalabrutinib (
Calquence
) or ibrutinib (Imbruvica) and developed a second primary malignancy.
The rate of developing a second primary neoplasia in patients with CLL treated with this class of agents was 7.6% at 3 years
.
AussieNeil
Administrator
in
CLL Support
5 years ago
Fatigue
I'm on
Calquence
, 2x/daily, 100mg.
I'm on
Calquence
, 2x/daily, 100mg.
fdshulman
in
CLL America Support
5 years ago
Financial Assistance for Acalabrutinib on Medicare
For those on Acalbrutinib/
Calquence
- if you are on Medicare is there financial assitance from the drug manufacturer to help cover the cost of the drug? If I start it now while I'm working, they provide a patient assistance discount but I could not find info about assistance if on Medicare.
For those on Acalbrutinib/
Calquence
- if you are on Medicare is there financial assitance from the drug manufacturer to help cover the cost of the drug? If I start it now while I'm working, they provide a patient assistance discount but I could not find info about assistance if on Medicare.
ReneeSusan
in
CLL America Support
5 years ago
Moving to Calquence from Ibrutinib
Anyone else on
Calquence
?
Anyone else on
Calquence
?
Mellyjake
in
CLL Support
5 years ago
NO amitryptiline while on Imbuverica or Calquence
Please do not take it if you are on imbuverica or
calquence
.
Please do not take it if you are on imbuverica or
calquence
.
profrich
in
CLL Support
5 years ago
Imbruvic to Calquence due to heart rhythm probems
I had heart rhythm problems in imbruvica and am switching to
calquence
. Is there anyone who has done this? If, so did the rhythm problems (PVC, Afib) not come back on
calquence
?
I had heart rhythm problems in imbruvica and am switching to
calquence
. Is there anyone who has done this? If, so did the rhythm problems (PVC, Afib) not come back on
calquence
?
profrich
in
CLL Support
5 years ago
Update on no amitryptiline when taking Imbruvica or Calquence
He said amitryptiline is a definite no when on Imbruvica or
Calquence
. It lengthens the QT interval, which can lead to arrhythmia. However, he said 1-2 nightly drinks is okay.
He said amitryptiline is a definite no when on Imbruvica or
Calquence
. It lengthens the QT interval, which can lead to arrhythmia. However, he said 1-2 nightly drinks is okay.
profrich
in
CLL Support
5 years ago
Anyone taking calquence (acalabrutinib)?
My doctor wants me to take
calquence
(acalabrutinib). However, I am even afraid of that after my experience with imbruvica. I am leaning towards immunotherapy. Is anyone on
calquence
? If, is all going okay? Thanks, Rich
My doctor wants me to take
calquence
(acalabrutinib). However, I am even afraid of that after my experience with imbruvica. I am leaning towards immunotherapy. Is anyone on
calquence
? If, is all going okay? Thanks, Rich
profrich
in
CLL Support
5 years ago
Imbruvica plus alcohol or amitryptiline yields Afib?
I am now switching to
calquence
. I have two drinks every night. I googled and learned that alcohol can trigger Afib. So, I wonder if drinking plus imbruvica triggered the arrhythmia. I have never had a heart problem, and an echocardium and cat scan shows everything is in good shape.
I am now switching to
calquence
. I have two drinks every night. I googled and learned that alcohol can trigger Afib. So, I wonder if drinking plus imbruvica triggered the arrhythmia. I have never had a heart problem, and an echocardium and cat scan shows everything is in good shape.
profrich
in
CLL Support
5 years ago
New drug soon...Acalabrutinic (Calquence) will have less side effects than Imbruvica.
J C Byrd has helped to develop 2ND generation BTK inhibitor -
Calquence
which will be available this year. Let us all hope for newer drugs - they have saved my life !! Without IB ,i was almost gone. So far, CLL is forever, and cannot be cured !
J C Byrd has helped to develop 2ND generation BTK inhibitor -
Calquence
which will be available this year. Let us all hope for newer drugs - they have saved my life !! Without IB ,i was almost gone. So far, CLL is forever, and cannot be cured !
mhrh
in
CLL Support
6 years ago
Encouraging results from son of Ibrutinib studies (Acalabrutinib/Calquence)
https://cancer.osu.edu/news-and-media/news/second-generation-btk-inhibitor-highly-effective-safe-as-solo-therapy-in-adult-leukemia [i]Title changed so information on Acalabrutinib/
Calquence
can be found via Search - Admin[/i]
https://cancer.osu.edu/news-and-media/news/second-generation-btk-inhibitor-highly-effective-safe-as-solo-therapy-in-adult-leukemia [i]Title changed so information on Acalabrutinib/
Calquence
can be found via Search - Admin[/i]
AdrianUK
in
CLL Support
6 years ago
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