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Epigenetic therapy (decitabine) shows promise for endocrine-resistant breast cancer
Using a low dose of the epigenetic therapy drug decitabine, which is currently used to treat some blood cancers, the researchers significantly suppressed the growth of endocrine resistant
breast
tumours
in mice and increased survival time by 90%.
Using a low dose of the epigenetic therapy drug decitabine, which is currently used to treat some blood cancers, the researchers significantly suppressed the growth of endocrine resistant
breast
tumours
in mice and increased survival time by 90%.
Split
in
SHARE Metastatic Breast Cancer
4 months ago
Could Morphine accelerate prostate cancer progression?
I was looking up wether morphine can activate mast cells and found the following: “We demonstrate that morphine does not influence cancer initiation, but it stimulates the progression of spontaneously developed
breast
tumours
and shortens the survival of tumour-bearing mice.
I was looking up wether morphine can activate mast cells and found the following: “We demonstrate that morphine does not influence cancer initiation, but it stimulates the progression of spontaneously developed
breast
tumours
and shortens the survival of tumour-bearing mice.
markrichardson
in
Advanced Prostate Cancer
7 months ago
New DX
I am a 76 yo woman. I was DX in 2016 and was in a trial at MD Anderson from 2017-2019. I achieved UMRD at the end of the trial of Ibrutinib and Venetoclax. I remained in total remission until my first visit after my husband died from Alzheimer’s in Oct 2021. Since then it’s been downhill. Dr Wierda
I am a 76 yo woman. I was DX in 2016 and was in a trial at MD Anderson from 2017-2019. I achieved UMRD at the end of the trial of Ibrutinib and Venetoclax. I remained in total remission until my first visit after my husband died from Alzheimer’s in Oct 2021. Since then it’s been downhill. Dr Wierda
pkpayne
in
CLL Support
3 days ago
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WHAT SHOULD I AVOID TAKING WITH IBRANCE
I am a Nigerian ,a single lady of 32years ,I was diagnosed of metastatic breast cancer on September 2023 then I redid my biopsy for a second opinion and it was same ,so I underwent 8chemo of Paclitaxel and carboplatin, which was 3weeks regimen from October 2023 to March 2023 ,afterwards a chest CT was
I am a Nigerian ,a single lady of 32years ,I was diagnosed of metastatic breast cancer on September 2023 then I redid my biopsy for a second opinion and it was same ,so I underwent 8chemo of Paclitaxel and carboplatin, which was 3weeks regimen from October 2023 to March 2023 ,afterwards a chest CT was
RuchiM
in
SHARE Metastatic Breast Cancer
7 days ago
Digoxin
Can I start Digoxin while still weaning off of Lopressor? Doc said stop lopressor and start dig no weaning needed I am a little nervous after all I read Thanks for Comments
Can I start Digoxin while still weaning off of Lopressor? Doc said stop lopressor and start dig no weaning needed I am a little nervous after all I read Thanks for Comments
farewelltoarms
in
Atrial Fibrillation Support
13 days ago
mastectomy now tamoxifen
I’m 48 and just had a double mastectomy almost 4 weeks ago. My bc tumor was 1.2 cm and ER/PR positive and HER 2 negative with an onco type score of 21 and nymph nodes were negative. I was hoping I was done with treatment, but was told I need to take tamoxifen. I read a lot of horrible stories about
I’m 48 and just had a double mastectomy almost 4 weeks ago. My bc tumor was 1.2 cm and ER/PR positive and HER 2 negative with an onco type score of 21 and nymph nodes were negative. I was hoping I was done with treatment, but was told I need to take tamoxifen. I read a lot of horrible stories about
Lulu427
in
SHARE Breast Cancer Support
13 days ago
Hay fever medicines
I continue to have badly blocked ears and a runny nose for several weeks. I’ve only managed to see paramedics rather than a GP about it. I haven’t used any nasal sprays (other than saline) but would like to try anti-allergy medication such as antihistamine. Yet I’ve read that “A few common stimulating
I continue to have badly blocked ears and a runny nose for several weeks. I’ve only managed to see paramedics rather than a GP about it. I haven’t used any nasal sprays (other than saline) but would like to try anti-allergy medication such as antihistamine. Yet I’ve read that “A few common stimulating
Samazeuilh2
in
Atrial Fibrillation Support
15 days ago
What next? re maintenance for HGS recurrence
Would love to know if any ladies who has also been unsuccessful with Olaparib, what has been a successful maintenance for you? I’ve just got 2 cycles more of Carbo/Caelyx, min scan showed slight reduction not as good as hoped for. Only maintenance mentioned by oncologist is to go on Letrozole. I
Would love to know if any ladies who has also been unsuccessful with Olaparib, what has been a successful maintenance for you? I’ve just got 2 cycles more of Carbo/Caelyx, min scan showed slight reduction not as good as hoped for. Only maintenance mentioned by oncologist is to go on Letrozole. I
Towergirl
in
My Ovacome
17 days ago
Trying to follow a healthy lifestyle while on long term drug therapy
So finding my lump and realising I had Breast Cancer has taken me on a strange journey. I'm a healthy active 75 year old carer for my darling hubby. I am starting month 6 of Letrozole, have had 1 Ibandronic acid treatment and have just been taken off my Abemeciclib tablets after almost 8 weeks as
So finding my lump and realising I had Breast Cancer has taken me on a strange journey. I'm a healthy active 75 year old carer for my darling hubby. I am starting month 6 of Letrozole, have had 1 Ibandronic acid treatment and have just been taken off my Abemeciclib tablets after almost 8 weeks as
wackier
in
SHARE Breast Cancer Support
23 days ago
how much to raise by?
I’m taking tamoxifen for breast cancer. It had impacted thyroid levels in the autumn but I only adjusted by a little. Latest test was tsh 5.17 and t4 17 (not taken that day) on 125 for 3 days a week and 100 for 4 days a week. Obviously I’m not very with it now. I think it has been like this for
I’m taking tamoxifen for breast cancer. It had impacted thyroid levels in the autumn but I only adjusted by a little. Latest test was tsh 5.17 and t4 17 (not taken that day) on 125 for 3 days a week and 100 for 4 days a week. Obviously I’m not very with it now. I think it has been like this for
haggisplant
in
Thyroid UK
28 days ago
Clinical trial update
Trial Drugs: Inavolisib and Giredestrant. Today was my second set of scans (every 8 weeks) and the results of the chest CT and Bone scans were great, nothing new, all stable and NED in lungs. The abdomen CT showed slight increase in the size of my liver lesions. I am ER+, HER2 low +1, PR-, AR+, with
Trial Drugs: Inavolisib and Giredestrant. Today was my second set of scans (every 8 weeks) and the results of the chest CT and Bone scans were great, nothing new, all stable and NED in lungs. The abdomen CT showed slight increase in the size of my liver lesions. I am ER+, HER2 low +1, PR-, AR+, with
Trissh
in
SHARE Metastatic Breast Cancer
1 month ago
Letrozole
I saw the oncologist yesterday to discuss radiotherapy and hormone therapy.The plan for radiotherapy is on hold ATM because I have an ongoing issue with a seroma on the breast and underarm. During the meeting she said she would give me a prescription for Letrozole, I told her I wasn't happy to start
I saw the oncologist yesterday to discuss radiotherapy and hormone therapy.The plan for radiotherapy is on hold ATM because I have an ongoing issue with a seroma on the breast and underarm. During the meeting she said she would give me a prescription for Letrozole, I told her I wasn't happy to start
LindaLittleBear
in
My Breast Cancer Community
1 month ago
Oil of Evening Primrose
I had a lumpectomy last May. It was a small ductal carcinoma which was invasive. I went on to have Radiotherapy and started a five year course of Letrozole. I developed bad joint pain and I had a month off to see if the Letrozole was the culprit. It was better but not gone. The oncology nurse suggested
I had a lumpectomy last May. It was a small ductal carcinoma which was invasive. I went on to have Radiotherapy and started a five year course of Letrozole. I developed bad joint pain and I had a month off to see if the Letrozole was the culprit. It was better but not gone. The oncology nurse suggested
Tabbycat64
in
My Breast Cancer Community
1 month ago
Question about tumor markers
Hi there, happy spring to all!! My Mom’s been doing well with trial med in combination with Faslodex monthly. Her blood work has been normal with good liver function. Her tumor marker test (the CA 15-3) test showed in the 350 range. I’m not sure it’s ever been that high but it was in the 150 range
Hi there, happy spring to all!! My Mom’s been doing well with trial med in combination with Faslodex monthly. Her blood work has been normal with good liver function. Her tumor marker test (the CA 15-3) test showed in the 350 range. I’m not sure it’s ever been that high but it was in the 150 range
Pups2Cute
in
SHARE Metastatic Breast Cancer
1 month ago
Exemestane and Afinitor
Hi everyone I just completed 1 month of Truqap. I had to stop treatment due to a cough and a horrible rash. I had to stay in the ER for 24 hours due to the rash. I am now moving on to Exemestane and Afinitor. I would so appreciate any experience that anyone has had on these 2 meds. I’m mostly interested
Hi everyone I just completed 1 month of Truqap. I had to stop treatment due to a cough and a horrible rash. I had to stay in the ER for 24 hours due to the rash. I am now moving on to Exemestane and Afinitor. I would so appreciate any experience that anyone has had on these 2 meds. I’m mostly interested
Jhshl512
in
SHARE Metastatic Breast Cancer
1 month ago
Breast dimpling post Lumpectomy?
Hi there! Anyone notice breast dimpling after lumpectomy? It has been 6 months after my surgery and I’m seeing 2 distinct dimples showing in the surgery area. I’m thinking it could be from the scar tissue?
Hi there! Anyone notice breast dimpling after lumpectomy? It has been 6 months after my surgery and I’m seeing 2 distinct dimples showing in the surgery area. I’m thinking it could be from the scar tissue?
NeenJah
in
SHARE Breast Cancer Support
1 month ago
Lizzietish
'Benign' cyst removed and has turned out to be in my bones and lungs and obviously in my skin. ER, PR + and HER-. All my research tells me I am doomed as skin mets are meant to be terminal?????? My oncology team were so upbeat, started on Letrozole and Ribociclib and Denosumab. I have no symptoms
'Benign' cyst removed and has turned out to be in my bones and lungs and obviously in my skin. ER, PR + and HER-. All my research tells me I am doomed as skin mets are meant to be terminal?????? My oncology team were so upbeat, started on Letrozole and Ribociclib and Denosumab. I have no symptoms
Lizzietosh
in
SHARE Metastatic Breast Cancer
1 month ago
Radiation for cancer other than thyroid.
Does radiation treatment for breast cancer affect thyroid medications? Does dose need to be adjusted during or after treatment?
Does radiation treatment for breast cancer affect thyroid medications? Does dose need to be adjusted during or after treatment?
raglansleeve
in
Thyroid UK
2 months ago
Acute Liver Failure Diagnosis
On Tuesday, I finally received the long awaited Truqap. I was told to hold off beginning treatment and to bring the medicine to the oncologist's off on Thursday. The oncologist took one look at me and dropped her jaw in awe of my yellow skin color, which I could not see, then shipped me off to the
On Tuesday, I finally received the long awaited Truqap. I was told to hold off beginning treatment and to bring the medicine to the oncologist's off on Thursday. The oncologist took one look at me and dropped her jaw in awe of my yellow skin color, which I could not see, then shipped me off to the
jersey-jazz
in
SHARE Metastatic Breast Cancer
2 months ago
TP53 Testing
Good afternoon. My oncologist called me last month to tell me that my FISH test indicated that I had Trisomy 12. He went on to say “You should feel lucky that you don’t have TP53.” I watched this excellent video yesterday. The doctors discussed the importance of having the separate TP53 test with FISH
Good afternoon. My oncologist called me last month to tell me that my FISH test indicated that I had Trisomy 12. He went on to say “You should feel lucky that you don’t have TP53.” I watched this excellent video yesterday. The doctors discussed the importance of having the separate TP53 test with FISH
Hidden
in
CLL Support
2 months ago
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