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Know your Biomarker … Know Your Mutation
KRAS mutation in colorectal cancer is an abnormal change in the KRAS gene, which is involved in controlling cell growth and survival. 40% of CRC has a KRAS mutation. There are more than 25 ongoing clinical trials studying treatments for KRAS-mutated colorectal cancer. Learn more about the KRAS biomarker
KRAS mutation in colorectal cancer is an abnormal change in the KRAS gene, which is involved in controlling cell growth and survival. 40% of CRC has a KRAS mutation. There are more than 25 ongoing clinical trials studying treatments for KRAS-mutated colorectal cancer. Learn more about the KRAS biomarker
GCCA-Survivor
Administrator
in
Colon Cancer Connected
4 months ago
Pinostilbene inhibits the Enz-resistant CRPC cell line by inhibiting AR variant 7
i take pterostilbene daily which pinostilbene is a metabolite of pterostilbene. in any event if you are failing on enzalutamide or any PCa warrior you probably should take pterostilbene. Below is a 2023 in-depth article https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550987/ Pinostilbene inhibits
i take pterostilbene daily which pinostilbene is a metabolite of pterostilbene. in any event if you are failing on enzalutamide or any PCa warrior you probably should take pterostilbene. Below is a 2023 in-depth article https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10550987/ Pinostilbene inhibits
KocoPr
in
Fight Prostate Cancer
6 months ago
PSA +
Is a PSA increase from .13 to .20 a concern? I'm on Eligard and Zytiga & Prednisone + Xgeva.
Is a PSA increase from .13 to .20 a concern? I'm on Eligard and Zytiga & Prednisone + Xgeva.
TommyCarz2
in
Advanced Prostate Cancer
6 months ago
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Back MRI Showed Pelvic Mass
Hello all! I am new here, so this is my first post. I had a back MRI in September 2023 in preparation for possible back surgery. The results of the MRI showed a pelvic mass in the area of left ovary. I took this information to my Gyn, who referred me to a GynOnc because of my age (65), the results
Hello all! I am new here, so this is my first post. I had a back MRI in September 2023 in preparation for possible back surgery. The results of the MRI showed a pelvic mass in the area of left ovary. I took this information to my Gyn, who referred me to a GynOnc because of my age (65), the results
retiredteacher1
in
My Ovacome
6 months ago
Studies help explain why some prostate cancers become resistant to hormone therapy
https://www.sciencedaily.com/releases/2023/12/231204135037.htm
https://www.sciencedaily.com/releases/2023/12/231204135037.htm
zeitgeistxx
in
Advanced Prostate Cancer
6 months ago
Avodart and Flomax
Hello brothers. Is it safe to use Avodart and Flomax with advanced prostate cáncer? I am tired of getting up to pee 7 or 8 times a night.
Hello brothers. Is it safe to use Avodart and Flomax with advanced prostate cáncer? I am tired of getting up to pee 7 or 8 times a night.
CountryJoe
in
Advanced Prostate Cancer
6 months ago
What do you think?
I’ve been on Lupron and Xgeva since 2014 and have had many other treatments along the way. As my PSA rose I found my best treatment was Xtandi. I had pretty good results from 2017 to 2020 , then my PSA moved upward again. Looks like I’m going to fail with Nubeqa, which I have been on for 2 1/2 months
I’ve been on Lupron and Xgeva since 2014 and have had many other treatments along the way. As my PSA rose I found my best treatment was Xtandi. I had pretty good results from 2017 to 2020 , then my PSA moved upward again. Looks like I’m going to fail with Nubeqa, which I have been on for 2 1/2 months
docbulldog
in
Advanced Prostate Cancer
6 months ago
updated scans post chemo
My dad has done 2 rounds of chemo, the third was delayed by hospitalization for sepsis. He has also had 10 rounds of radiation. His third round will be near Christmas and they completed scans to compare to his pre chemo scans. His full body bone scans state the following “Diffuse skeletal metastatic
My dad has done 2 rounds of chemo, the third was delayed by hospitalization for sepsis. He has also had 10 rounds of radiation. His third round will be near Christmas and they completed scans to compare to his pre chemo scans. His full body bone scans state the following “Diffuse skeletal metastatic
StayingSTRNG
in
Advanced Prostate Cancer
6 months ago
Break from ADT or not?
Hi everyone, my Dad was recommended 18-24 months of Lupron/Zytiga/Prednisone after Radiation Therapy. We reached that time and MO said that is up to my Dad if he wants to continue the treatment or not. Lately my dad had high blood pressure over 200 and he ended up in ER, but now the blood pressure is
Hi everyone, my Dad was recommended 18-24 months of Lupron/Zytiga/Prednisone after Radiation Therapy. We reached that time and MO said that is up to my Dad if he wants to continue the treatment or not. Lately my dad had high blood pressure over 200 and he ended up in ER, but now the blood pressure is
Simonapo
in
Advanced Prostate Cancer
6 months ago
Lupron and prostate cancer
hi everyone. im a 67 year old man taking Lupron hormone deprivation for prostate cancer. i finished receiving 20 external beam radiation treatments in August 2023. the Lupron injections are quarterly and will continue for 18-24 months. my interest in sex has completely dropped off. i assume this is normal
hi everyone. im a 67 year old man taking Lupron hormone deprivation for prostate cancer. i finished receiving 20 external beam radiation treatments in August 2023. the Lupron injections are quarterly and will continue for 18-24 months. my interest in sex has completely dropped off. i assume this is normal
rolex1951
in
Advanced Prostate Cancer
6 months ago
Bleeding when opening the bowels
does anyone else get this? I had to have an emergency appointment today as I went to the toilet and when I opened my bowels and looked in the toilet, the water and bowl were full of blood! I had confirmed stage 2 endo on my bladder and ovary, I’ve also had mumtiple colonoscopies, sigmoidoscopies, endoscopies
does anyone else get this? I had to have an emergency appointment today as I went to the toilet and when I opened my bowels and looked in the toilet, the water and bowl were full of blood! I had confirmed stage 2 endo on my bladder and ovary, I’ve also had mumtiple colonoscopies, sigmoidoscopies, endoscopies
nikogirl18
in
Endometriosis UK
4 months ago
hole in windpipe
I’m 3 years post Ivor Lewis, 2023 scan showed cancer in lymph node in neck had chemo and radiation, the radiation has now caused a hole in my windpipe that makes my saliva go down wrong pipe, causing chest infections just out of hospital after phenomena. Constant coughing . They first said could put
I’m 3 years post Ivor Lewis, 2023 scan showed cancer in lymph node in neck had chemo and radiation, the radiation has now caused a hole in my windpipe that makes my saliva go down wrong pipe, causing chest infections just out of hospital after phenomena. Constant coughing . They first said could put
Von66
in
Oesophageal & Gastric Cancer
2 months ago
PSA rise after RP
Hi all. First post on this board. Seems like I can learn a lot. Stressing out over my psa results this week. Highest since RP 8 years ago. Has been as follows: 2015…<.03 2016.. 0.020 2017…0.021 2018…0.028 2019…0.024 2020…0.029 2021…0.029 2022…0.03 2023…0.05 so my concern is the almost double
Hi all. First post on this board. Seems like I can learn a lot. Stressing out over my psa results this week. Highest since RP 8 years ago. Has been as follows: 2015…<.03 2016.. 0.020 2017…0.021 2018…0.028 2019…0.024 2020…0.029 2021…0.029 2022…0.03 2023…0.05 so my concern is the almost double
LockItUp
in
Prostate Cancer Network
6 months ago
Provenge Complete
Well folks, I completed Provenge with no issues or SE’s to note. I understand my PSA will not be lowered by this treatment and it has gone way up, from 24 first of October to 58 last week. I am still waiting to hear from Sarah Cannon Research to review possible clinical trials. In a way I feel like
Well folks, I completed Provenge with no issues or SE’s to note. I understand my PSA will not be lowered by this treatment and it has gone way up, from 24 first of October to 58 last week. I am still waiting to hear from Sarah Cannon Research to review possible clinical trials. In a way I feel like
Pmann
in
Advanced Prostate Cancer
6 months ago
positive HPV smear test
I had my smear test last week and after having smear tests for years this one has come back HPV positive with abnormal cells called low grade dyskaryosis and I’m being sent for a colposcopy. I’m so stressed what does this mean do I have cervical cancer??
I had my smear test last week and after having smear tests for years this one has come back HPV positive with abnormal cells called low grade dyskaryosis and I’m being sent for a colposcopy. I’m so stressed what does this mean do I have cervical cancer??
DDolly
in
Endometriosis UK
6 months ago
And more ASCO GU 2024 phase 3 trial
Data will be presented at ASCO GU 2024 but looks promising "In combination with immunotherapy, Cabometyx is delivering long-term survival benefits today for people living with renal cell carcinoma worldwide, while also showcasing future potential in metastatic castration-resistant prostate cancer, an
Data will be presented at ASCO GU 2024 but looks promising "In combination with immunotherapy, Cabometyx is delivering long-term survival benefits today for people living with renal cell carcinoma worldwide, while also showcasing future potential in metastatic castration-resistant prostate cancer, an
Maxone73
in
Advanced Prostate Cancer
4 months ago
Big bleed
Oh my, juat need to vent a little. Im in the uk wales. Last night I had a really big bleed, for context I'm pregnant via IVF 6w6d and I'm on clexane (warfarin) due to a problem with clotting. I was advised to go A&E , after waiting 4 hours I got triage, and was told I will need to wait a minimum 12 hrs
Oh my, juat need to vent a little. Im in the uk wales. Last night I had a really big bleed, for context I'm pregnant via IVF 6w6d and I'm on clexane (warfarin) due to a problem with clotting. I was advised to go A&E , after waiting 4 hours I got triage, and was told I will need to wait a minimum 12 hrs
Tanzytilly
in
Fertility Network UK - Pregnancy Support
5 days ago
225Ac-J591 Yields Responses in Difficult-to-Treat Metastatic Prostate Cancer
It seems to work better on visceral and bone metastatis... https://www.cancertherapyadvisor.com/home/news/conference-coverage/suo-2023/225ac-j591-yields-responses-in-difficult-to-treat-metastatic-prostate-cancer/
It seems to work better on visceral and bone metastatis... https://www.cancertherapyadvisor.com/home/news/conference-coverage/suo-2023/225ac-j591-yields-responses-in-difficult-to-treat-metastatic-prostate-cancer/
Maxone73
in
Advanced Prostate Cancer
6 months ago
Recurrence after prostatectomy
I have a relative who had surgery 6.5 years ago. Pathology was very favorable, 3+3+tertiary 4 i.e. less than 5%, no pos margins, no ECE, no nodes. He remained undetectable for 6.5 years, but now is .07 verified. What would SOC be for him? Prostate bed or wide radiation, length of ADT, just Lupron or
I have a relative who had surgery 6.5 years ago. Pathology was very favorable, 3+3+tertiary 4 i.e. less than 5%, no pos margins, no ECE, no nodes. He remained undetectable for 6.5 years, but now is .07 verified. What would SOC be for him? Prostate bed or wide radiation, length of ADT, just Lupron or
Fred312
in
Advanced Prostate Cancer
6 months ago
BROQ/Prostaphane
Last week I had my 3 monthly PSA check and was happy and surprised to see that it had remained unchanged at 0.07. It had previously been creeping up and I am not currently on any treatement since my Cyberknife to a lymph node in December 21 together with 6 months of bicalutamide. I take a large variety
Last week I had my 3 monthly PSA check and was happy and surprised to see that it had remained unchanged at 0.07. It had previously been creeping up and I am not currently on any treatement since my Cyberknife to a lymph node in December 21 together with 6 months of bicalutamide. I take a large variety
GreenStreet
in
Fight Prostate Cancer
6 months ago
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