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Overall Survival With [177]Lu-PSMA-617 vs Cabazitaxel in Metastatic Castration-Resistant Prostate Cancer
The Lancet Oncology TAKE-HOME MESSAGE TheraP was a phase II trial that compared the efficacy of radioligand therapy with 177Lu-PSMA-617 with that of cabazitaxel in patients with metastatic castration-resistant prostate cancer who had previously received docetaxel. After a median follow-up of 35.7 months
The Lancet Oncology TAKE-HOME MESSAGE TheraP was a phase II trial that compared the efficacy of radioligand therapy with 177Lu-PSMA-617 with that of cabazitaxel in patients with metastatic castration-resistant prostate cancer who had previously received docetaxel. After a median follow-up of 35.7 months
Magnus1964
in
Advanced Prostate Cancer
5 months ago
Criteria for "my ADT has stopped working and we have to move to another"
Hello - So my third post ADT initiation (Lupron+Abi) PSA test is coming up and since it was <.1 six weeks ago, I asked how the criteria of “has stopped working” works -to my Hopkins MO and I got this - “We want to declare a therapy no longer effective when PSA is clearly going up. We look for 0.3
Hello - So my third post ADT initiation (Lupron+Abi) PSA test is coming up and since it was <.1 six weeks ago, I asked how the criteria of “has stopped working” works -to my Hopkins MO and I got this - “We want to declare a therapy no longer effective when PSA is clearly going up. We look for 0.3
jackwfrench
in
Advanced Prostate Cancer
5 months ago
Advice on thyroid results
Hello I would be grateful if anyone could pass any comments on my thyroid results. I am feeling really ill can hardly get out of bed and my mood really low, this has been going on for a long time now and struggling to know how to proceed. Had total thyroid and parathyroid removal in august 2022 found
Hello I would be grateful if anyone could pass any comments on my thyroid results. I am feeling really ill can hardly get out of bed and my mood really low, this has been going on for a long time now and struggling to know how to proceed. Had total thyroid and parathyroid removal in august 2022 found
Cbreeze1961
in
Thyroid UK
5 months ago
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reaction to carboplatin
I’m on my second recurrence and currently on carbo/gemcitabine.. ive had a reaction on last three cycles each one being harder than the last.. my question is has this happened to anyone else and , if so what was was the outcome? It’s been mentioned they may slow carb infusion over Two hour period
I’m on my second recurrence and currently on carbo/gemcitabine.. ive had a reaction on last three cycles each one being harder than the last.. my question is has this happened to anyone else and , if so what was was the outcome? It’s been mentioned they may slow carb infusion over Two hour period
SKpaints1
in
My Ovacome
5 months ago
4 years after thyroidectomy
total thyroidectomy for papillaire carcinoma my tsh is 0.5 on levo 75 Thyroglobulin =1 after my USS found a little nodes in thyroid area noother nodes detected my endo whant me to be off levo 1 month to do scintigraphy is there any other way to kow if my cancer is back . Thanks guy for feed back
total thyroidectomy for papillaire carcinoma my tsh is 0.5 on levo 75 Thyroglobulin =1 after my USS found a little nodes in thyroid area noother nodes detected my endo whant me to be off levo 1 month to do scintigraphy is there any other way to kow if my cancer is back . Thanks guy for feed back
Raoudha
in
Thyroid UK
2 months ago
Proton Treatment - When to start the ADT relative to simulation and CT of the prostate
I am talking to two radiologists who have a strong difference of opinion. One radiologist tells me I should start ADT two months before I do the space OAR, markers and simulation, and then start the radiation. Another doctor tells me I should start the ADT at the same time as I do the space OAR and simulation
I am talking to two radiologists who have a strong difference of opinion. One radiologist tells me I should start ADT two months before I do the space OAR, markers and simulation, and then start the radiation. Another doctor tells me I should start the ADT at the same time as I do the space OAR and simulation
CBRD
in
Advanced Prostate Cancer
2 months ago
Tried Bovine Thyroid Supplement - feel very ill!
I could really use some help. I just started on a beef thyroid supplement this morning (Grassfed Beef Thyroid by Ancestral Supplements). And it looks like my body is reacting the same way it reacted when I tried 2 porcine thyroid supplements in the past - heart palpitations and severe fatigue. Although
I could really use some help. I just started on a beef thyroid supplement this morning (Grassfed Beef Thyroid by Ancestral Supplements). And it looks like my body is reacting the same way it reacted when I tried 2 porcine thyroid supplements in the past - heart palpitations and severe fatigue. Although
Betterhealth4me
in
Thyroid UK
5 months ago
Prostate cancer
My prostate condition started around eight years ago when I had urinary track infection which also led to prostatitis. Ever since then, my PSA jumped from 2 to 7.8 during the last 5 years. I had two biopsies… first one, four years ago, they detected no positive cancer cells in my prostate. However
My prostate condition started around eight years ago when I had urinary track infection which also led to prostatitis. Ever since then, my PSA jumped from 2 to 7.8 during the last 5 years. I had two biopsies… first one, four years ago, they detected no positive cancer cells in my prostate. However
Yuncoinc7148
in
Fight Prostate Cancer
5 months ago
Lymparza not working
hi..my husband was initially diagnosed stage 4b in 2020. He did well on chemo, and lupron. He is also on xgeva. He then went on zytiga for about 7 months before it started failing. He did get accepted in the luteciun trial at Penn on control arm. He did very well on Xtandi but was ended this past Aug
hi..my husband was initially diagnosed stage 4b in 2020. He did well on chemo, and lupron. He is also on xgeva. He then went on zytiga for about 7 months before it started failing. He did get accepted in the luteciun trial at Penn on control arm. He did very well on Xtandi but was ended this past Aug
Happy1985
in
Advanced Prostate Cancer
5 months ago
new diagnosis
Hi I am new here. 49 and Just had the results of my ct scan and it’s looking like lung cancer not much more info. I have no symptoms apart from a sore shoulder blade, I was referred for a chest xray in Dec after having a bad cough from what I think was covid. I have a biopsy on the 3rd and should have
Hi I am new here. 49 and Just had the results of my ct scan and it’s looking like lung cancer not much more info. I have no symptoms apart from a sore shoulder blade, I was referred for a chest xray in Dec after having a bad cough from what I think was covid. I have a biopsy on the 3rd and should have
Clairemc0974
in
The Roy Castle Lung Cancer Foundation
5 months ago
Still confused about PSA and Testosterone testing
I have been reading posts here for some time and there seems to be a split between those who only get PSA tests each time they go to their doctors and those that get both tests each time. I had a baseline testosterone test before Lupron and before radiation. I am now doing my 6 month follow up and
I have been reading posts here for some time and there seems to be a split between those who only get PSA tests each time they go to their doctors and those that get both tests each time. I had a baseline testosterone test before Lupron and before radiation. I am now doing my 6 month follow up and
Mgtd
in
Advanced Prostate Cancer
5 months ago
Sterlings Reply
Please forgive the lateness but here it is:Four years after prostectomy my psa began to rise. I had eight weeks of radiation to the prostate bed. Psa returned to nondetectable for eleven years. Two years ago my psa began to rise at an alarming rate it was doubling monthly if not more. I started eligard
Please forgive the lateness but here it is:Four years after prostectomy my psa began to rise. I had eight weeks of radiation to the prostate bed. Psa returned to nondetectable for eleven years. Two years ago my psa began to rise at an alarming rate it was doubling monthly if not more. I started eligard
Praying2BHealthy
in
Advanced Prostate Cancer
5 months ago
Mom doing great with Faslodex with trial med
Happy Friday everyone! My Mom had her second Faslodex injections yesterday and has almost no soreness at site. Yay! She is also very energetic and feels well. She’s thinks maybe the treatment is making her even more energetic than usual (she’s very active and a young 77yrs) lol 😆 She’s involved
Happy Friday everyone! My Mom had her second Faslodex injections yesterday and has almost no soreness at site. Yay! She is also very energetic and feels well. She’s thinks maybe the treatment is making her even more energetic than usual (she’s very active and a young 77yrs) lol 😆 She’s involved
Pups2Cute
in
SHARE Metastatic Breast Cancer
10 months ago
Did not see that coming.
Hello to all, Dx 11-1-23. Went in with urinary situations and came out with a Turp and stage 4. had a Psma pet scan ..Mets here and there . So high volume I guess. PSA was 139 ..MO says triplet therapy ....seems like I'm pretty far down the road... I know I gain by doing the therapy but on average are
Hello to all, Dx 11-1-23. Went in with urinary situations and came out with a Turp and stage 4. had a Psma pet scan ..Mets here and there . So high volume I guess. PSA was 139 ..MO says triplet therapy ....seems like I'm pretty far down the road... I know I gain by doing the therapy but on average are
APK3
in
Advanced Prostate Cancer
5 months ago
Practical Sexual Restoration Techniques from Mayo Clinic Urologist
Click here for your free Prostate Cancer video channel subscription. https://www.youtube.com/c/malecare?sub_confirmation=1 SUPPORT OUR PROSTATE CANCER COMMUNITY - PLEASE DONATE NOW https://malecare.org/donate Real world sexual restoration techniques. Dr. Kohler explains what he tells his patients
Click here for your free Prostate Cancer video channel subscription. https://www.youtube.com/c/malecare?sub_confirmation=1 SUPPORT OUR PROSTATE CANCER COMMUNITY - PLEASE DONATE NOW https://malecare.org/donate Real world sexual restoration techniques. Dr. Kohler explains what he tells his patients
Darryl
Partner
in
Advanced Prostate Cancer
5 months ago
Practical Sexual Restoration Techniques from Mayo Clinic Urologist
https://youtu.be/Gj_xuTOJzkY Please click on this link to create a free Prostate Cancer video channel subscription. https://www.youtube.com/c/malecare?sub_confirmation=1 SUPPORT OUR PROSTATE CANCER COMMUNITY> PLEASE DONATE NOW https://malecare.org/donate Real world sexual restoration techniques
https://youtu.be/Gj_xuTOJzkY Please click on this link to create a free Prostate Cancer video channel subscription. https://www.youtube.com/c/malecare?sub_confirmation=1 SUPPORT OUR PROSTATE CANCER COMMUNITY> PLEASE DONATE NOW https://malecare.org/donate Real world sexual restoration techniques
Darryl
Partner
in
Prostate Cancer Network
5 months ago
Importance of ADT
Are there any good outcomes without using ADT ( hormone therapy)? I delayed it for a couple of years with bad results. My history -- [u]
2021
[/u]: Age 78. PSA was 7.79, Gleason 4+3=7. Small lesion in prostate, with perineural invasion. Had 20 IMRT for prostate. No ADT. [u]
2022
[/u]: PSA
Are there any good outcomes without using ADT ( hormone therapy)? I delayed it for a couple of years with bad results. My history -- [u]
2021
[/u]: Age 78. PSA was 7.79, Gleason 4+3=7. Small lesion in prostate, with perineural invasion. Had 20 IMRT for prostate. No ADT. [u]
2022
[/u]: PSA
vintage42
in
Advanced Prostate Cancer
5 months ago
Next steps after PBRT
Hi all - First and foremost, Happy Holidays. I had my prostate removed 8/22, with subsequent Proton Beam treatment ending 4/23 (after PSA did not drop to undetectable) brought upon after a mild uptake (during a Petscan) in an obturator lymph node. I’m on Orgovyx and Xtandi, with a plan to stay on them
Hi all - First and foremost, Happy Holidays. I had my prostate removed 8/22, with subsequent Proton Beam treatment ending 4/23 (after PSA did not drop to undetectable) brought upon after a mild uptake (during a Petscan) in an obturator lymph node. I’m on Orgovyx and Xtandi, with a plan to stay on them
Vp7174
in
Advanced Prostate Cancer
5 months ago
HRT, any thoughts please
He said he wouldn't recommend it for me because of increases in
breast
cancer
, also it could raise my Bp and put on weight and a risk of cardio problems. He said keep losing weight and come back in 3 months, which seems like a long time when l am waking up wet from sweating etc.
He said he wouldn't recommend it for me because of increases in
breast
cancer
, also it could raise my Bp and put on weight and a risk of cardio problems. He said keep losing weight and come back in 3 months, which seems like a long time when l am waking up wet from sweating etc.
RubyKB
in
Menopause and Perimenopause Support
1 year ago
Androgen Receptor Activity (ARA) for BAT
I read somewhere (here?) that ARA is a good predictor of BAT efficacy and that Johns Hopkins has a test for it. I have been trying to track down such a test, at Johns Hopkins or elsewhere, with no success. Any suggestions? Androgen receptor activity in prostate cancer dictates efficacy of bipolar
I read somewhere (here?) that ARA is a good predictor of BAT efficacy and that Johns Hopkins has a test for it. I have been trying to track down such a test, at Johns Hopkins or elsewhere, with no success. Any suggestions? Androgen receptor activity in prostate cancer dictates efficacy of bipolar
cigafred
in
Fight Prostate Cancer
5 months ago
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