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Mitochondrial Protections for Aging Humans PartII
Mitochondrial Antioxidants 1) Coenzyme Q10 -Ubiquinone (CoQ10) Coenzyme Q10 (CoQ10) is considered the "mitochondrial specific antioxidant". It is an essential component of the mitochondrial electron transport chain. It is also an antioxidant in cellular membranes and lipoproteins. All
Mitochondrial Antioxidants 1) Coenzyme Q10 -Ubiquinone (CoQ10) Coenzyme Q10 (CoQ10) is considered the "mitochondrial specific antioxidant". It is an essential component of the mitochondrial electron transport chain. It is also an antioxidant in cellular membranes and lipoproteins. All
MateoBeach
in
Fight Prostate Cancer
1 year ago
Ambroxol and Parkinson’s
a clinical trial of ambroxol called ‘Ambroxol to Slow Progression in Parkinson’, or the ‘ASPro – PD’ trial, will begin. This is a large phase 3 clinical trial to determine if ambroxol can slow or stop Parkinson’s. It is led by Professor Anthony Schapira at University College London and is funded by Cure
a clinical trial of ambroxol called ‘Ambroxol to Slow Progression in Parkinson’, or the ‘ASPro – PD’ trial, will begin. This is a large phase 3 clinical trial to determine if ambroxol can slow or stop Parkinson’s. It is led by Professor Anthony Schapira at University College London and is funded by Cure
Farooqji
in
Cure Parkinson's
1 year ago
Look after yourself!
Hi everyone, as you will know from previous posts, my hubby has decompensated liver and is still drinking, with an "If I die, I die" attitude. So today saw me at the GP for myself (felt a bit self indulgent tbh) and I've got low haemoglobin, low vitamin levels, possibly due to Covid a couple of months
Hi everyone, as you will know from previous posts, my hubby has decompensated liver and is still drinking, with an "If I die, I die" attitude. So today saw me at the GP for myself (felt a bit self indulgent tbh) and I've got low haemoglobin, low vitamin levels, possibly due to Covid a couple of months
MrsWorried
in
British Liver Trust
2 years ago
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Exercise and Afib
I'm sure you all already know this but I discovered this recently. My cardiologist sent me to cardiac rehab because I have afib and some wall weakening in the heart. The idea is to strengthen the heart muscle to be able to handle any arrhythmia that may come my way. I always thought that talk
I'm sure you all already know this but I discovered this recently. My cardiologist sent me to cardiac rehab because I have afib and some wall weakening in the heart. The idea is to strengthen the heart muscle to be able to handle any arrhythmia that may come my way. I always thought that talk
Elsie1955
in
Atrial Fibrillation Support
2 years ago
Immunocompromised
I’m currently in a clinical trial receiving infusions of a drug similar to rituximab, and therefore immunocompromised. I am a public employee and in a battle with my employer. I was working remotely for 2 years, and my job is easily accomplished remotely. They are now requiring me to come back full
I’m currently in a clinical trial receiving infusions of a drug similar to rituximab, and therefore immunocompromised. I am a public employee and in a battle with my employer. I was working remotely for 2 years, and my job is easily accomplished remotely. They are now requiring me to come back full
MsAmyM
in
Kidney Disease
1 year ago
BIOVAS clinical trial for Non-ANCA associated vasculitis.
Vasculitis UK is supporting the BIOVAS trial by sharing their project to help them recruit patients. If you are interested, please contact your local team to discuss it.
Vasculitis UK is supporting the BIOVAS trial by sharing their project to help them recruit patients. If you are interested, please contact your local team to discuss it.
zoe69
Vasculitis UK
in
Vasculitis UK
1 year ago
A New Cell Therapy Trial for MF
Not sure if this has come up before. This company is focused on improving SCT for bone cancers with a new agent, Orca-T. https://orcabio.com/clinical-programs/ A phase 2 trial for MF had this result among others: "Regression of marrow fibrosis to MF grade 0 or 1 was noted by D+ 100 in 7 of 7 Orca-T
Not sure if this has come up before. This company is focused on improving SCT for bone cancers with a new agent, Orca-T. https://orcabio.com/clinical-programs/ A phase 2 trial for MF had this result among others: "Regression of marrow fibrosis to MF grade 0 or 1 was noted by D+ 100 in 7 of 7 Orca-T
EPguy
in
MPN Voice
1 year ago
Taking part in Watchman trial to establish if it’s safe to come off anti-coagulants like Apixaban
Good afternoon everyone. On Thursday I am scheduled to go for a procedure to have a Watchman device fitted inside my heart at John Radcliffe Hospital here in Oxford under supervision of the Cardiac Research Team. I volunteered to do this as part of a world wide trial covering 3000 patients to assess
Good afternoon everyone. On Thursday I am scheduled to go for a procedure to have a Watchman device fitted inside my heart at John Radcliffe Hospital here in Oxford under supervision of the Cardiac Research Team. I volunteered to do this as part of a world wide trial covering 3000 patients to assess
JefferyW
in
Atrial Fibrillation Support
2 years ago
Chemo (Docetaxel) with Prednisone
Hi all, Zytiga stopped working for me and I am castrate-resistant. After a failed clinical trial (immunotherapy) I started Docetaxel 2 weeks ago and was prescribed Prednisone (5mg twice per day). I seem to be very sensitive to the Prednisone....having trouble sleeping, feeling anxious, etc. even when
Hi all, Zytiga stopped working for me and I am castrate-resistant. After a failed clinical trial (immunotherapy) I started Docetaxel 2 weeks ago and was prescribed Prednisone (5mg twice per day). I seem to be very sensitive to the Prednisone....having trouble sleeping, feeling anxious, etc. even when
carguy
in
Advanced Prostate Cancer
1 year ago
Grateful for any Feedback on PVI Ablation Please
Hi, My background is:- Developed Atrial Fibrillation in November 2021 (persistent from day 1). Had a cardioversion in February 2022, which lasted about 7 weeks and then back into persistent AF, looking back I carried on as normal after the cardioversion and perhaps I should have been more careful.
Hi, My background is:- Developed Atrial Fibrillation in November 2021 (persistent from day 1). Had a cardioversion in February 2022, which lasted about 7 weeks and then back into persistent AF, looking back I carried on as normal after the cardioversion and perhaps I should have been more careful.
Hidden
in
AF Association
2 years ago
11 clinical trials that will shape medicine in 2023
https://www.nature.com/articles/s41591-022-02132-3
https://www.nature.com/articles/s41591-022-02132-3
Farooqji
in
Cure Parkinson's
1 year ago
Modified Citrus Pectin - reply from Dr Eliaz
A member asked me to post the reply I was to get from Dr Isaac Eliaz on MCP, Modified Citrus Pectin / Pectasol and I do this. Below is my communication with dr Eliaz, generously facilitated by AnnieAppleseed, followed by excerpts from two studies. Dr. Eliaz writes that 80 % of patients with BRPC,
A member asked me to post the reply I was to get from Dr Isaac Eliaz on MCP, Modified Citrus Pectin / Pectasol and I do this. Below is my communication with dr Eliaz, generously facilitated by AnnieAppleseed, followed by excerpts from two studies. Dr. Eliaz writes that 80 % of patients with BRPC,
Purple-Bike
in
Advanced Prostate Cancer
1 year ago
Have any Vagal Afibbers tried exercising before bed?
As I have Vagal Afib I can switch it off early on in an episode with a Valsalva maneuver. A few nights ago I could not stop the Afib as it did not wake me immediately, so I could not stop it the usual way. I had read that some people exercise during Afib, so rather than pop another Flecainide pill I
As I have Vagal Afib I can switch it off early on in an episode with a Valsalva maneuver. A few nights ago I could not stop the Afib as it did not wake me immediately, so I could not stop it the usual way. I had read that some people exercise during Afib, so rather than pop another Flecainide pill I
OzRob
in
AF Association
2 years ago
Doxycycline
Bottom Line: Low-dose Doxycycline may be a useful add-on to other therapies, for a number of reasons: i) inhibition of mitochondrial protein synthesis, with decreased ATP and a slowing of proliferation ... ii) ... &, with a particularly detrimental effect on PCa stem cell-like cells iii) inhibition
Bottom Line: Low-dose Doxycycline may be a useful add-on to other therapies, for a number of reasons: i) inhibition of mitochondrial protein synthesis, with decreased ATP and a slowing of proliferation ... ii) ... &, with a particularly detrimental effect on PCa stem cell-like cells iii) inhibition
pca2004
in
Fight Prostate Cancer
1 year ago
A New Clinical Trial for Pain and Fibrosis in Chronic Pancreatitis!
Hi everyone! I wanted to announce that there's a new clinical trial testing proglumide for pain and fibrosis in chronic pancreatitis patients that is currently recruiting participants in the Washington, D.C. area! We helped design this trial, but we need your help to find participants and get this drug
Hi everyone! I wanted to announce that there's a new clinical trial testing proglumide for pain and fibrosis in chronic pancreatitis patients that is currently recruiting participants in the Washington, D.C. area! We helped design this trial, but we need your help to find participants and get this drug
Skye_MC
Administrator
in
Chronic Pancreatitis Support
1 year ago
Melatonin
Had a great night... took 200mg Gabapentin,( from a high of 600 mg. 4 days ago) 10 mg. Melatonin and Reduced Requip to .75 mg from 1 mg. I hadnt mentioned i am following the low glutamine diet as well. It is so rare to feel good . My heart goes out to thise suffering. I think the melatonin is
Had a great night... took 200mg Gabapentin,( from a high of 600 mg. 4 days ago) 10 mg. Melatonin and Reduced Requip to .75 mg from 1 mg. I hadnt mentioned i am following the low glutamine diet as well. It is so rare to feel good . My heart goes out to thise suffering. I think the melatonin is
Truthsword
in
Restless Legs Syndrome
2 years ago
Update on progress with MF and the FEDORA clinical trial
So to recap, I was diagnosed with primary MF in October 2022 and asked to join a new clinical trial called FEDORA. After many tests including a BMB, ultrasound on my abdomen, chest X-ray etc. I started on the pre medication of 400mg/day (in one dose) of Fedratinib in capsule form. This was the first
So to recap, I was diagnosed with primary MF in October 2022 and asked to join a new clinical trial called FEDORA. After many tests including a BMB, ultrasound on my abdomen, chest X-ray etc. I started on the pre medication of 400mg/day (in one dose) of Fedratinib in capsule form. This was the first
Flyingsteamer
in
MPN Voice
1 year ago
Niacin and Butyrate: Nutraceuticals Targeting Dysbiosis and Intestinal Permeability in Parkinson’s Disease
[u]
"Future studies should study the effects of long-term supplementation of promising nutrients, such as butyrate and niacin, on their abilities to halt or reverse disease progression in PD. "
[/u] Niacin and Butyrate: Nutraceuticals Targeting Dysbiosis and Intestinal Permeability in Parkinson
[u]
"Future studies should study the effects of long-term supplementation of promising nutrients, such as butyrate and niacin, on their abilities to halt or reverse disease progression in PD. "
[/u] Niacin and Butyrate: Nutraceuticals Targeting Dysbiosis and Intestinal Permeability in Parkinson
Bolt_Upright
in
Cure Parkinson's
1 year ago
Should I have an ablation?
Fortunately I’ve not had a repeat of the
atrial
flutter
. I’ve been told by the cardiac nurse that I’ve been referred for an ablation. I’m wondering if I need it? I’m in constant sinus rhythm now and the meds seem to be keeping the
atrial
flutter
at bay.
Fortunately I’ve not had a repeat of the
atrial
flutter
. I’ve been told by the cardiac nurse that I’ve been referred for an ablation. I’m wondering if I need it? I’m in constant sinus rhythm now and the meds seem to be keeping the
atrial
flutter
at bay.
Anon2023
in
British Heart Foundation
2 years ago
Docetaxel Extends Enzalutamide Effectiveness
This is our first proof that resistance to enzalutamide can be reduced with docetaxel. It also shows that triplet therapy may be beneficial in patients who have already progressed to castration resistance. We would expect a larger effect if used at the first sign of castration resistance. https://www.prostatecancer.news
This is our first proof that resistance to enzalutamide can be reduced with docetaxel. It also shows that triplet therapy may be beneficial in patients who have already progressed to castration resistance. We would expect a larger effect if used at the first sign of castration resistance. https://www.prostatecancer.news
Tall_Allen
in
Advanced Prostate Cancer
2 years ago
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