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Potential therapeutic effects and pharmacological evidence of sinomenine in central nervous system disorders
Published online 2022 Sep 16, I realize it is a rat study, but it is sinomenine is used in Traditional Chinese Medicine. Pharmacological effects of sinomenine in Parkinson’s disease PD is a common neurodegenerative disorder characterized by progressive degeneration of dopaminergic neurons in the
Published online 2022 Sep 16, I realize it is a rat study, but it is sinomenine is used in Traditional Chinese Medicine. Pharmacological effects of sinomenine in Parkinson’s disease PD is a common neurodegenerative disorder characterized by progressive degeneration of dopaminergic neurons in the
Sydney75
in
Cure Parkinson's
6 months ago
Here we go again!
Well I went off my meds in late July. I have done well and now things are acting up again. Going to start Trintellex tonight. I was on mirtazapine but was starting to gain weight. Part of my anxiety is starting up new medication as well. Ugh how I do not like this at all!
Well I went off my meds in late July. I have done well and now things are acting up again. Going to start Trintellex tonight. I was on mirtazapine but was starting to gain weight. Part of my anxiety is starting up new medication as well. Ugh how I do not like this at all!
Ladytrue
in
Anxiety and Depression Support
8 months ago
Serum ferritin level & RBC count help please
Hi there, just wondered If anyone could please tell me if a Ferritin level of 44ng/ml and a RBC count of 3.76 (whilst actually already taking Ferrous Fumerate 210mg twice per day) is still pretty low and ‘could’ maybe be the reason I’m still feeling exhausted/heavy tired legs?? Thank you in advance
Hi there, just wondered If anyone could please tell me if a Ferritin level of 44ng/ml and a RBC count of 3.76 (whilst actually already taking Ferrous Fumerate 210mg twice per day) is still pretty low and ‘could’ maybe be the reason I’m still feeling exhausted/heavy tired legs?? Thank you in advance
CandiR
in
Pernicious Anaemia Society
6 months ago
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Losing track of where you are while driving
Have you ever lost track of where you are while driving? I've probably had this occur 3-4 times in the last year in places I have gone to many times. Twice this was when I was approaching a street where I had to turn. Suddenly I didn't know if I needed to keep going or turn, or had taken the wrong
Have you ever lost track of where you are while driving? I've probably had this occur 3-4 times in the last year in places I have gone to many times. Twice this was when I was approaching a street where I had to turn. Suddenly I didn't know if I needed to keep going or turn, or had taken the wrong
Doxy46
in
MPN Voice
6 months ago
I'm stuck
Depression isn't like people think. It's not sadness. It's a weight. I don't feel like doing anything except eating and playing video games. I know exercise would help. But I can't get myself to do it. I know talking to loved ones would help. But I can't figure out how to make a call. I manage
Depression isn't like people think. It's not sadness. It's a weight. I don't feel like doing anything except eating and playing video games. I know exercise would help. But I can't get myself to do it. I know talking to loved ones would help. But I can't figure out how to make a call. I manage
Sharkweek178
in
Anxiety and Depression Support
8 months ago
Bolt's Failed Pickle Experiment (Lectins) :(
First off, for those who don't know me, I have NOT been diagnosed with PD
. I was diagnosed with REM Sleep Behavior Disorder back in April 21, which the experts say will lead to PD or something worse. When I was diagnosed I did have some other odd symptoms. Mild balance issues, Seborrheic dermatitis
First off, for those who don't know me, I have NOT been diagnosed with PD
. I was diagnosed with REM Sleep Behavior Disorder back in April 21, which the experts say will lead to PD or something worse. When I was diagnosed I did have some other odd symptoms. Mild balance issues, Seborrheic dermatitis
Bolt_Upright
in
Cure Parkinson's
6 months ago
Legal Advice?
Hi All, Although this post is not MS-related, I wanted to reach out to my MSAA Community for their input. Perhaps someone here can point me in the right direction, as I don't really have the money to hire an attorney. Unfortunately, this situation doesn't lend itself to any "free advice and/or attorneys
Hi All, Although this post is not MS-related, I wanted to reach out to my MSAA Community for their input. Perhaps someone here can point me in the right direction, as I don't really have the money to hire an attorney. Unfortunately, this situation doesn't lend itself to any "free advice and/or attorneys
DM0329
in
My MSAA Community
6 months ago
Light at end of tunnel?
Finally withdrawal done. No more depression meds. Lost 10 lbs and head clearer. Still dealing with cheating spouse. Closing on new home in another state..with him. Only thing good about it is will be so much closer to my family. Still suffer from panic attacks but thankfully few and far between. I
Finally withdrawal done. No more depression meds. Lost 10 lbs and head clearer. Still dealing with cheating spouse. Closing on new home in another state..with him. Only thing good about it is will be so much closer to my family. Still suffer from panic attacks but thankfully few and far between. I
Hidden
in
Anxiety and Depression Support
8 months ago
I want to help if I can
I have be dx in1986 w/ RRMS, I had be misdiagnosed approximately 5 times, one of the Dr.s telling me to quit my job in a jail because I was a woman. Long story short I went completely paralyzed and in a rehab for approximately 6 weeks. I learned to walk, talk, adl, etc until my release when I went
I have be dx in1986 w/ RRMS, I had be misdiagnosed approximately 5 times, one of the Dr.s telling me to quit my job in a jail because I was a woman. Long story short I went completely paralyzed and in a rehab for approximately 6 weeks. I learned to walk, talk, adl, etc until my release when I went
BlondiePink
in
My MSAA Community
7 months ago
I really need to vent
Do you ever just not want to bother anyone else? I do, I'd almost would rather suffer in silence. I've been suffering with depression, anxiety, and adhd. The last year has been the worst after a seperation from my ex fiance with 2 kids involved. I self isolate myself and try to ignore everything. I
Do you ever just not want to bother anyone else? I do, I'd almost would rather suffer in silence. I've been suffering with depression, anxiety, and adhd. The last year has been the worst after a seperation from my ex fiance with 2 kids involved. I self isolate myself and try to ignore everything. I
Joemamba13
in
Anxiety and Depression Support
5 months ago
Anxiety
Been suffering g with anxiety all my life. Started having anxiety attacks at 18. Depression too. Looking to discuss with others manageable techniques and a forum to discuss with same. 🙂
Been suffering g with anxiety all my life. Started having anxiety attacks at 18. Depression too. Looking to discuss with others manageable techniques and a forum to discuss with same. 🙂
ArloGuthrie
in
Anxiety and Depression Support
5 months ago
I don’t care which supplement is working.
I feel awesome; the combo could be placebo. Today I took: - 2 scoops of Inulin and a Probiotic first thing in the morning. My whole body felt tingly for 45 minutes. (Tingly may be the wrong word, it wasn’t unpleasant, more like a glow.) - Hour later: 1 Neurogan’s Urolithin A 700mg, 1 Fatty15, 1-1/
I feel awesome; the combo could be placebo. Today I took: - 2 scoops of Inulin and a Probiotic first thing in the morning. My whole body felt tingly for 45 minutes. (Tingly may be the wrong word, it wasn’t unpleasant, more like a glow.) - Hour later: 1 Neurogan’s Urolithin A 700mg, 1 Fatty15, 1-1/
Gcf51
in
Cure Parkinson's
7 days ago
Swimming and my OCD journey
Hi all, I've suffered with OCD most of my adult life but am thankful to have found this social platform. I've never belonged to an online health community before. Over summer, I rediscovered my love for swimming and it drastically reduces my OCD. My OCD is so bad I usually can't stay at home for an
Hi all, I've suffered with OCD most of my adult life but am thankful to have found this social platform. I've never belonged to an online health community before. Over summer, I rediscovered my love for swimming and it drastically reduces my OCD. My OCD is so bad I usually can't stay at home for an
quicklyinsignificant
in
Anxiety and Depression Support
9 days ago
(Very) Irregular Periods Post Recovery
Hello, I wanted to ask if anyone in this community experienced persistent menstrual dysfunction following recovery from anorexia? For some background, I had anorexia from ages 11 - 18. I reached the menarche (had my first period) at 17, following weight restoration. My eating patterns and BMI have
Hello, I wanted to ask if anyone in this community experienced persistent menstrual dysfunction following recovery from anorexia? For some background, I had anorexia from ages 11 - 18. I reached the menarche (had my first period) at 17, following weight restoration. My eating patterns and BMI have
Capybara571
in
Talk ED (eating disorders)
7 months ago
Mirtazapine
Hi I've not posted for a very long time.I've been on 15mg for quite a few years now. Has anyone increased to 22.5mg and how have you felt? I upped it a couple of years ago but if I remember I split the doses as it was all too much in one go I used to take the lower dose in the morning. I'm going
Hi I've not posted for a very long time.I've been on 15mg for quite a few years now. Has anyone increased to 22.5mg and how have you felt? I upped it a couple of years ago but if I remember I split the doses as it was all too much in one go I used to take the lower dose in the morning. I'm going
Charl-
in
Anxiety Support
5 months ago
Health Anxiety coping tips
anyone got some good ones? In a pretty bad bout right now and some of my old strategies don’t seem to be cutting it. Restarted medication 3 weeks ago but not noticing much help yet with the obsessive thoughts and ruminations. Appreciate any positive suggestions. Thanks.
anyone got some good ones? In a pretty bad bout right now and some of my old strategies don’t seem to be cutting it. Restarted medication 3 weeks ago but not noticing much help yet with the obsessive thoughts and ruminations. Appreciate any positive suggestions. Thanks.
BasketK
in
Anxiety and Depression Support
24 days ago
sexual OCD?
does anyone else have sexual OCD? Just figured out that’s what has been contributing to my anxiety/depression over the years
does anyone else have sexual OCD? Just figured out that’s what has been contributing to my anxiety/depression over the years
Slinkygoldfish
in
Anxiety and Depression Support
27 days ago
The Endotoxin Hypothesis of Parkinson's Disease
Abstract:
The endotoxin hypothesis of Parkinson's disease (PD) is the idea that lipopolysaccharide (LPS) endotoxins contribute to the pathogenesis of this disorder. LPS endotoxins are found in, and released from, the outer membrane of Gram-negative bacteria, for example in the gut. It is proposed
Abstract:
The endotoxin hypothesis of Parkinson's disease (PD) is the idea that lipopolysaccharide (LPS) endotoxins contribute to the pathogenesis of this disorder. LPS endotoxins are found in, and released from, the outer membrane of Gram-negative bacteria, for example in the gut. It is proposed
Bolt_Upright
in
Cure Parkinson's
7 months ago
Ran out of Buserelin - FET
Hi, I was scheduled for my last Buserelin injection on Thursday ahead of FET next week (Thursday). I thought I had just enough left in the vial but there were only a few drops when I drew it up so I didn't get a full injection (or anything close) Initially I wasn't worried, my lining looked good at D9
Hi, I was scheduled for my last Buserelin injection on Thursday ahead of FET next week (Thursday). I thought I had just enough left in the vial but there were only a few drops when I drew it up so I didn't get a full injection (or anything close) Initially I wasn't worried, my lining looked good at D9
GreenOpera
in
Fertility Network UK
9 months ago
Has anyone here gotten weight restored on their own without going to a nutritionist or eating disorder center?
I have anorexia nervosa and I have been to several treatment centers and seen several nutritionists in my life. They have never helped me as far as yes they help me gain the weight but then I don't end up getting my mind changed any even with all the psychotherapy so it ends up doing me no good. What
I have anorexia nervosa and I have been to several treatment centers and seen several nutritionists in my life. They have never helped me as far as yes they help me gain the weight but then I don't end up getting my mind changed any even with all the psychotherapy so it ends up doing me no good. What
Hidden
in
Talk ED (eating disorders)
7 months ago
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