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Another victory for "triplet"therapy for newly diagnosed metastatic men.
Last year, the PEACE1 trial showed that the combination of abiraterone+docetaxel+ADT, all started at the same time, increased survival by over 1 ½ years in men with high volume metastases (we are awaiting data for low volume). Similarly, the triplet of darolutamide+docetaxel+ADT, started simultaneously
Last year, the PEACE1 trial showed that the combination of abiraterone+docetaxel+ADT, all started at the same time, increased survival by over 1 ½ years in men with high volume metastases (we are awaiting data for low volume). Similarly, the triplet of darolutamide+docetaxel+ADT, started simultaneously
Tall_Allen
in
Advanced Prostate Cancer
2 years ago
Is anyone on ADT taking collagen for joint pain and bone health?
Is anyone on ADT taking collagen for joint pain and bone health? I am stage four on Eldergaurd (Lupron) and Xtandi, a met in the hips and one in the spine. I am taking several supplements including calcium and D3. Should I be taking collagen?
Is anyone on ADT taking collagen for joint pain and bone health? I am stage four on Eldergaurd (Lupron) and Xtandi, a met in the hips and one in the spine. I am taking several supplements including calcium and D3. Should I be taking collagen?
de-luke
in
Advanced Prostate Cancer
2 years ago
Need ADT advice
I expect to get my first Lupron shot this week as an appetizer for staring RT in about 2 months. Reading all the side effects of Lupron gives me the willies. I can deal with man boobs, maybe even hot flashes and mood changes. I am more concerned about the cognitive impact of ADT, bone loss, muscle tone
I expect to get my first Lupron shot this week as an appetizer for staring RT in about 2 months. Reading all the side effects of Lupron gives me the willies. I can deal with man boobs, maybe even hot flashes and mood changes. I am more concerned about the cognitive impact of ADT, bone loss, muscle tone
Teaker
in
Advanced Prostate Cancer
2 years ago
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Alternatives to osteoporosis meds?
Hi all— I read that they offer hormone therapy in Europe, ( even to older women in their 70’s) but not in the US. I asked an Osteo doc why and and she said because we’re not Europe! Can anyone offer any answers along with other alternatives to the current batch of meds —-as they have quite significant
Hi all— I read that they offer hormone therapy in Europe, ( even to older women in their 70’s) but not in the US. I asked an Osteo doc why and and she said because we’re not Europe! Can anyone offer any answers along with other alternatives to the current batch of meds —-as they have quite significant
Wyaatch
in
Osteoarthritis Action
2 years ago
Need help for next step
My father dignisted G score 3+5 And PSA 60 with about 10 bone met lungs and ... Other part of body Our doctor started taxoter and zometa for 3, years ago and also we start ADT each 3 month After chemo finished we just stay on ADT zolodex During this time my father start fasting therapy do to our
My father dignisted G score 3+5 And PSA 60 with about 10 bone met lungs and ... Other part of body Our doctor started taxoter and zometa for 3, years ago and also we start ADT each 3 month After chemo finished we just stay on ADT zolodex During this time my father start fasting therapy do to our
saeed_alexy
in
Fight Prostate Cancer
2 years ago
my friends i have very important question about surgery after metastases
My father dignisted G score 3+5 And PSA 60 with about 10 bone met lungs and ... Other part of body Our doctor started taxoter and zometa for 3, years ago and also we start ADT each 3 month After chemo finished we just stay on ADT zolodex During this time my father start fasting therapy do to our
My father dignisted G score 3+5 And PSA 60 with about 10 bone met lungs and ... Other part of body Our doctor started taxoter and zometa for 3, years ago and also we start ADT each 3 month After chemo finished we just stay on ADT zolodex During this time my father start fasting therapy do to our
saeed_alexy
in
Advanced Prostate Cancer
2 years ago
Timing of Androgen Deprivation Treatment for Men with Biochemical Recurrent Prostate Cancer in the Context of Novel Therapies
https://healthunlocked.com/redirect?url=https%3A%2F%2Fwww.auajournals.org%2Fdoi%2F10.1097%2FJU.0000000000001797 Published September, 2021 Conclusions Men with biochemically recurrent prostate cancer, who defer hormone therapy until metastasis have overall survival that is quite long and the early initiation
https://healthunlocked.com/redirect?url=https%3A%2F%2Fwww.auajournals.org%2Fdoi%2F10.1097%2FJU.0000000000001797 Published September, 2021 Conclusions Men with biochemically recurrent prostate cancer, who defer hormone therapy until metastasis have overall survival that is quite long and the early initiation
maley2711
in
Prostate Cancer Network
2 years ago
Timing of Androgen Deprivation Treatment for Men with Biochemical Recurrent Prostate Cancer in the Context of Novel Therapies
https://www.auajournals.org/doi/10.1097/JU.0000000000001797 Published September, 2021 Conclusions Men with biochemically recurrent prostate cancer, who defer hormone therapy until metastasis have overall survival that is quite long and the early initiation of continuous androgen deprivation therapy
https://www.auajournals.org/doi/10.1097/JU.0000000000001797 Published September, 2021 Conclusions Men with biochemically recurrent prostate cancer, who defer hormone therapy until metastasis have overall survival that is quite long and the early initiation of continuous androgen deprivation therapy
maley2711
in
Advanced Prostate Cancer
2 years ago
Emerging Role of PSMA Imaging; Grand Rounds
Background: I had a PSMA PET done Jan21 while on ADT with very low PSA. The question from my RO was whether it was worth the effort? This study says that there could be a benefit from being on ADT during a PSMA PET...there are other indications to the contrary, but I though this was important. My
Background: I had a PSMA PET done Jan21 while on ADT with very low PSA. The question from my RO was whether it was worth the effort? This study says that there could be a benefit from being on ADT during a PSMA PET...there are other indications to the contrary, but I though this was important. My
RMontana
in
Active Surveillance - Prostate Cancer
2 years ago
Pretty quick failure of ADT + Zytiga... next?
Quick history: 2019 PSA of 20, a few probable spinal mets, bicalutamide monotherapy mid-2020 for six months failed early-2021 after PSA dropped to 3.8. Tried to initiate ADT via tE2 with estrogen patches in Spring 2021, but could not get T to castrate levels, stubbornly above 150 even at higher doses
Quick history: 2019 PSA of 20, a few probable spinal mets, bicalutamide monotherapy mid-2020 for six months failed early-2021 after PSA dropped to 3.8. Tried to initiate ADT via tE2 with estrogen patches in Spring 2021, but could not get T to castrate levels, stubbornly above 150 even at higher doses
noahware
in
Advanced Prostate Cancer
2 years ago
Advise on PSA Rise - .23 .46 .7 tested every 30 days. Still have prostate. T Level is 373. On ADT vacation since August of 2021.
Gleason 9. Local Lymph node involvement. I still have my prostate. Had HD Brachy and did radiation to my prostate and lymph nodes back in 2019. MY MO suggests to continue to watch the PSA and see if it levels out and if not then scan in a couple of months and not to panic. My PSA was .014 back in
Gleason 9. Local Lymph node involvement. I still have my prostate. Had HD Brachy and did radiation to my prostate and lymph nodes back in 2019. MY MO suggests to continue to watch the PSA and see if it levels out and if not then scan in a couple of months and not to panic. My PSA was .014 back in
Longterm101
in
Advanced Prostate Cancer
2 years ago
My 46 Month Transdermal Estradiol (tE2) Update
PSA - 0.006, T - 231, E2 - 162, ALP - 88 Actually I was quite pleased with my trimonthly blood test results that I recently received; however, after reading Tall_Allen's treatise (The Perils and Pitfalls of "Treating PSA" in Advanced Prostate Cancer), about how PSAs in men with advanced PCa can often
PSA - 0.006, T - 231, E2 - 162, ALP - 88 Actually I was quite pleased with my trimonthly blood test results that I recently received; however, after reading Tall_Allen's treatise (The Perils and Pitfalls of "Treating PSA" in Advanced Prostate Cancer), about how PSAs in men with advanced PCa can often
E2-Guy
in
Advanced Prostate Cancer
2 years ago
Dienogest or Hysterectomy?
Hi everyone, thank you for sharing your journeys. I've said this before, but this forum is a massive support for me. I don't post often but it's the first thing I open in the morning and would be lost without the feeling g of support I get from you all. I was wondering if anyone has been on Dienogest
Hi everyone, thank you for sharing your journeys. I've said this before, but this forum is a massive support for me. I don't post often but it's the first thing I open in the morning and would be lost without the feeling g of support I get from you all. I was wondering if anyone has been on Dienogest
Deemctee
in
Endometriosis UK
2 years ago
The Metabolic Syndrome [MetS] & PCa
The "Metabolic syndrome is a clustering of at least three of the following five medical conditions:
- abdominal obesity,
- high blood pressure,
- high blood sugar,
- high serum triglycerides,
and
- low serum high-density lipoprotein (HDL).
" [1] "In the
The "Metabolic syndrome is a clustering of at least three of the following five medical conditions:
- abdominal obesity,
- high blood pressure,
- high blood sugar,
- high serum triglycerides,
and
- low serum high-density lipoprotein (HDL).
" [1] "In the
pjoshea13
in
Advanced Prostate Cancer
2 years ago
A Little Joke
I saw an ad on Facebook today for a drug called “Saxenda”. I don’t know what it does. Got me thinking that ADT could be called “Sexenda”!
I saw an ad on Facebook today for a drug called “Saxenda”. I don’t know what it does. Got me thinking that ADT could be called “Sexenda”!
MJCA
in
Advanced Prostate Cancer
2 years ago
Statins: new study regarding time to CRPC
Quite a few statin posts in the past few months... not sure if this was among them, but is very recent. [Edited below] Hat tip to Richard Wassersug at LifeonADT.com for posting. https://pubmed.ncbi.nlm.nih.gov/35075214/ Abstract Background: Metabolic syndrome and its pharmacologic treatment can potentially
Quite a few statin posts in the past few months... not sure if this was among them, but is very recent. [Edited below] Hat tip to Richard Wassersug at LifeonADT.com for posting. https://pubmed.ncbi.nlm.nih.gov/35075214/ Abstract Background: Metabolic syndrome and its pharmacologic treatment can potentially
noahware
in
Advanced Prostate Cancer
2 years ago
ADT CHOICES
I'm on Firmagon once a month and it's working fine. The only problem is that I feel like garbage for 2 or 3 days after the shot. Is there any difference in effectiveness if I had a 6 month shot of Lupron or Eligard?
I'm on Firmagon once a month and it's working fine. The only problem is that I feel like garbage for 2 or 3 days after the shot. Is there any difference in effectiveness if I had a 6 month shot of Lupron or Eligard?
epfj3333
in
Advanced Prostate Cancer
2 years ago
Docetaxal
Can anyone advise generally speaking is docetaxal with ADT the best way forward at the outset Oncologist is saying that the addition of Abi + peridsone is not needed as low volume Thank you in advance
Can anyone advise generally speaking is docetaxal with ADT the best way forward at the outset Oncologist is saying that the addition of Abi + peridsone is not needed as low volume Thank you in advance
Farn
in
Advanced Prostate Cancer
2 years ago
Status on Xtandi effect
Hi Folks, you may remember I was speculating that the Xtandi dosage was designed in the clinical trials to be at the max possible without incurring adverse side effects. There was little attention paid to the efficacy of the doses. My theory was that while we need a high dose to reach saturation, we
Hi Folks, you may remember I was speculating that the Xtandi dosage was designed in the clinical trials to be at the max possible without incurring adverse side effects. There was little attention paid to the efficacy of the doses. My theory was that while we need a high dose to reach saturation, we
Stoneartist
in
Advanced Prostate Cancer
2 years ago
Newly-discovered Micro-Mets: What would you do?
Recent (my first) PSMA Pylarify scan shows I've acquired 9-10 tiny lymph node metastases scattered in the common iliac, mediastinal, and left supraclavicular regions of my body. I'm still hormone-sensitive, but would prefer not to go back on ADT if possible (history of heart concerns). Area radiation
Recent (my first) PSMA Pylarify scan shows I've acquired 9-10 tiny lymph node metastases scattered in the common iliac, mediastinal, and left supraclavicular regions of my body. I'm still hormone-sensitive, but would prefer not to go back on ADT if possible (history of heart concerns). Area radiation
SeattleDan
in
Advanced Prostate Cancer
2 years ago
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