Eribulin

[blms]

Okay ladies, who is on eribulin and what can you share with me?

Taxol has stopped working, cancer spread, feeling like this is it.

Bonnie

[Ardie1970]

Oh Bonnie sorry to hear this. I don’t know anything but what I read and it does seem some have had good results on this chemo.

[blms]

Your great and info is wonderful. I will read articles later tonight or tomorrow because I also love to go through anything scientific.Thanks for being my afternoon cheerleader. I often get a bit annoyed about everyone telling me I will be fine. But today, I need this.

[Ardie1970]

I just read these this morning before Bonnie posted. So glad you were able to link them!

[onjali]

I am on eribulin. I am starting my 6th cycle next week. Every cycle my tumor markers drop a little more. I am tolerating it okay, I give myself zarxio injections for 3 days after and it’s keeping my wbc count up. My main side effects are fatigue, little bit of nausea, and constipation. I do probiotic supplements and drinks daily that helps with the gastrointestinal issues. If you have any questions please feel free to reach out. I don’t check this board very often but my email is [e-mail]

[Sunnydrinking]

Hi Bonnie

I have completed my 4th cycle of eribulin. I have tolerated it very well and have only really suffered from fatigue.

I have also managed to keep all of my hair using the cold cap.

I am now waiting for recent scan results and just hoping it’s working well, especially on my stubborn liver mets 🤞

Very best wishes

Jo xx

[mariootsi in reply to Sunnydrinking]

Jo, wishing and praying for good scan results.

[Hidden in reply to Sunnydrinking]

Thinking of you Jo for results dayClare

[blms in reply to Sunnydrinking]

Hi Jo, How did you do with your scans?

Bonnie

[Clio58]

Hello Bonnie,I have been on Eribulin since the end of November, after progression on letrozole/ibrance and further progression with faslodex (I stayed on it only for three months)

I had a CT scan 2 weeks ago and my oncologist was very pleased with the results, my liver mets are shrinking in number and size!

Eribulin is taken on day 1 and 8 and then there is a two weeks break. After 48 hours I feel excessively tired, my WBC drops so I am given 2 subcutaneous injections to improve the WBC.

Apart from the fatigue lasting for 2/3 days and loosing my hair right away, I sometimes get heartburn and sores in the mouth, for which there are effective remedies

I wish you success on your new treatment

[blms in reply to Clio58]

THANK YOU to those that also responded about being on Eribulin. New drugs are always daunting. I have not actually seen my oncologist since my scan on Tuesday. But the NP told me three weeks on one off. I understand they can and do change med schedules. I did not hear about the shots and am wondering if that is just given in beginning or after issues with counts.

[Clio58 in reply to blms]

I didn't get the shots the first time, only after they saw the issues with WBC

[blms in reply to Clio58]

Where do you live and where are you being treated?

[Clio58 in reply to blms]

I live in Rome, Italy, I'm being treated at Policlinico Gemelli

[blms in reply to Clio58]

My family is from Italy. Both grandparents were born there. My grandmother and her family are from Palermo and my granddad a small town NE of Rome. Cannot remember the name right now. I have traveled to Italy a number of times. my favorite place!!

[blms in reply to Clio58]

Anyone on this board taking anything to increase appetite. I NEED to eat.

[Beryl71]

I cannot offer expertise but I see others can. I'll just send you my energy and zest for life and say, don't let go! Take care Carolyn x

[8576]

Glad you dropped in and got the advice that you did. We are here for you. I have no experience with Eriibulin. At least not yet. Haven't decided to go that route. Hope you find another drug to try.

Cheers, June S.

[geewisdom]

Well stated Sandra and thanks for the information share. Bonnie, we must turn all negative thoughts into positive thinking. I know it can be difficult at times but you are your biggest Fan. This is the time to ENCOURAGE yourself and speak LIFE to yourself and your body. Think about this, if you give up, then what........exactly why you cannot. There are so many new drugs and trials now, this is not the END!

[blms]

Hi Sandra,I think you already understand that I understand ALL of this and meaning. But, I know many facing these battles live in denial, I do not. I have been living this personally with cancer for 24 years. I understand positivity and impact, etc. I do a million complementary things in an effort to assist my healing. I am 72 and body already taken a beating. I am very positively realistic, not a dreamer, and not expecting the next great treatment to either being close by or being my "cure" which is ridiculous. One gets despondent then pulls their big girl pants up and gives it another college try until the body can't take anymore. AND I happen to have great faith which makes the road so much easier knowing what I have known my entire life as I came to this world with the gift of faith and that never leaves you. It does NOT mean that God chooses to heal me and when it is my time, it is my time. I only am very sad for my children and husband to have to go through all of this as I COMPLETELY understand where they are as I have been living their pain most of my life for 67 years and 48 of those with lose my incredible aunt and mother of breast cancer. So, I do not look at positive thinking as believing everything will be fine, etc.

[Totheriver]

So sorry th hear this Bonnie, hopefully the next treatment will work well.

[mariootsi]

So sorry you are in this situation, but Eribulin is very effective! Taxol didn't work for me either my first time around! Have hope. I'll be praying for you.

[blms in reply to mariootsi]

Actually, Taxol worked pretty well until my body figured it out. I was on it almost 11 months so I guess I out not complain. Hopefully the new drug will be similar in side effects. Bt I have noticed side effects are worse when cancer is worse and when it starts getting a bit better everything seems less.

[mariootsi in reply to blms]

Hopefully your side effects will be similar to taxol. Sounds like you tolerated it well.

[Topaz_77]

This is very helpful for me as well. I was supposed to start Eribulin this month after coming off of Xeloda but I have to delay a few weeks for now to do whole brain radiation since they found some brain mets after a recent fall I had. I’ve completed 5 sessions so far.

As far as I know, my oncologist is still planning to go forward with Eribulin following a period of time after radiation ends so I am looking forward to how I will be affected once I finally start it. She’s not really saying right now because the main focus at this time is these brain mets.

Right now, I have stubborn liver mets and but at least progression has been reasonably slow. Thank you for your informative post.

[blms in reply to Topaz_77]

Boy, I was surprised to know that Euriblin infusion is only 15 mins. (15 for pre meds as well). So, that is 1/3 the time that took taxol! Fast and pleasant actually--lightly cool going in. Maybe that is just me. I've only had one so far-tomorrow two!

[Missmaddie615]

So sorry to hear about your progression. There are so many more treatments out there. May this next treatment be manageable for you and kick the cancer back and may you be on it a very long time. Sending you a gentle hug - blessings to you 💗🙏

[blms]

I just read the studies. Thanks. Very helpful!! Love this kind of info and saved me a lot of time.

[blms]

100% agree with you and know that all to be true. I remember back in 1998 before they gave me A/C and asking, "what the heck and why are we still using these drugs to treat this that didn't change stats in over 50 years, seriously" Of course the answer I knew was that they had nothing else yet. They did start taxol and that was a help. So this is life.

[Hidden]

You are such a fighter and sounds like you will continue your journey with the next treatment.Get those big girl pants pulled right up

Clare

[blms]

of course! I love my oncology dietitian ! I keep in contact with her. I do think I will get ascites drained again soon. I do not want to wait and get as bad as I was last March.Also, I just read a PMC article about Ivermectin and it involved breast cancer as well as other cancers. It suggests that the drug family could be a great assistance to chemo with breast cancer but no clinical trials as yet. Reason I even looked it up is that my cousin, MBC, was just told that she was going to be taking it along with daily b12 shots. Although I have to go back and look at her bloodwork, I did not think she was that deficient. Other than energy and bringing reds up, any ideas why that is used for MBC? I get shots but only about once a month.

[blms]

Yes I get that!! Maybe a trial next year.

[blms]

Now, just realized that my mouth is yeasty looking. And maybe beginning ulcers. In my old age and stupidity, I was a bit surprised that I felt dehydrated (mouth obviously) and never looked at my tongue! Wake up Bonnie