Pregabalin Timing ?: So, Im going from... - Restless Legs Syn...

Restless Legs Syndrome

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Pregabalin Timing ?

C82021 profile image
3 Replies

So, Im going from Gabapentin (4-5yrs.) to pregabalin. My usual symptoms are from 8pm to 12pm. and I would say severe and most every night.( sometime varied throughout the day but rarely) Im to take 100mg Pregabalin twice a day. But at what times? I've tried 7pm and 9pm, then 5pm and 8:30pm. Im confused as to the spacing I should drive for. What say you?

FWIW: Most my troubles are before bed time. Once I fall asleep Im unaware of leg movement but it's there according to my wife.

Sometimes when the pills aren't cooperating, a gummy seems to help. (two, times a week)

Trying the garlic, ginger, honey mixture, I think it helps some. Teaspoon a day, 3-5pm. ( tastes terrible, breaths a little hard on others 🤷‍♂️)

Have a treadmill, this works the best when all others seem to fail. Turn on the DVD player and walk a mile. Works great.

"THANKS"

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C82021
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SueJohnson profile image
SueJohnson

You don't need to divide the doses. Normally you would take them 1 to 2 hours before bed. I remember you had vision problems on 1200 mg gabapentin but did it control your symptoms? If not, since the 200 mg of pregabalin is equivalent to the 1200 mg you might need more. The usual effective dose is 200 to 300 mg.

e365 profile image
e365

Hi, I take 300 mg pregabalin at night for my rls. I’ve experimented with dividing the doses and timing. Taking a dose in the am had no effect whatsoever on my rls. What works best for me is I have to take my dose at least two hours after eating dinner on an empty stomach. I have to be strict about this. The meds start to kick in about 90 minutes and then I have to go to bed because I feel drunk as a skunk. I’ve also found that I can not take any antacids after dinner or it blocks the effect of the pregabalin. Hope this helps.

Hoochybaby profile image
Hoochybaby

hi I have been taking Pregabalin for a number of years

I take 200 mg at night usually about 10pm

Some nights are better than others but I’ve also tried weighted socks with some success I also take 30 to 60mg codeine at night after the Pregabalin

Good luck

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