Is SBRT given Once a Week better than Every Other Day?

[janebob99]

Yes, according to a recent randomized, five-year Phase-III study by Zilli et al. (2023). Doing SBRT Once-a-Week significantly outperforms doing it Every-Other-Day (EOD), in terms of risk of having Biochemical Recurrence at 10 years.

pubmed.ncbi.nlm.nih.gov/370...

[Tall_Allen]

It does not say what you are posting. I know you don't understand statistics, but p values greater than 0.05 (it was 0.13) means that one must reject the null hypothesis of an unfavorable response rate. The null hypothesis in this case is that once a week is worse than every other day. So it means that so far, once-a-week is not worse than every-other-day, not that it "outperforms" it, as you wrongly wrote.

[janebob99 in reply to Tall_Allen]

Why do peer reviewed papers publish graphs like this, if they have no meaning?

[Tall_Allen in reply to janebob99]

They are written for fellow doctors who have a background in statistics and research methods. They are very meaningful. That was an "inferiority trial" and the curve so far proves that the new treatment schedule is not inferior. They are not written for patients like you who are completely ignorant about how to read them. If you want to understand how to read them, take at least a Statistics 101 course.

What you posted is called a Kaplan-Meier curve. When you draw a conclusion that is opposite to the conclusion drawn by the author, assume you are wrong. The editors and peer-reviewers wouldn't make that kind of mistake.