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Second opinion on biopsy

nvidia-ati profile image
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I very much appreciate all the kind words, support and advice I've recieved here on this forum. It has helped my journey. Here's a link to my original post:

healthunlocked.com/prostate...

I got a second opinion from John's Hopkins. I've included below an excerpt from the pathology results. Hopefullly, the pathologist that read my slides was trained by Dr. Epstein. It appears the original lab that created and read my biopsy slides only sent 2 of them to Hopkins. Is it normal for pathology labs to send just 2 slides instead off of all the slides from all the cores?

What do you advise my next steps should be? What serum and urine tests are available as advised by the Hopkins pathologist?

I also have an appointment to see another urologist at Hopkins: Dr. Arthur Louis Burnett who seems experienced.

SURGICAL PATHOLOGY: CONSULT - Details

Pathologist: Tamara Levin Lotan, MD

Specimen: Prostate:Needle Core Biopsy

UROLOGIC PATHOLOGY CONSULTATION SERVICE

1. Prostate (Needle Core Biopsy):

F. Prostate tissue with small focus of atypical glands, highly suspicious for low-grade carcinoma. See note.

NOTE: Although these findings are highly atypical and suspicious for adenocarcinoma, there is insufficient cytologic and/or architectural atypia to establish a definitive diagnosis. Followup is warranted with serum or urine tests and imaging, and in some cases, repeat biopsy with relative increased sampling of the atypical site may be recommended.

Stains for high molecular weight cytokeratin and p63 are positive in a patchy fashion in some of the glands.

This case was reviewed at the Genitourinary Pathology Quality Assurance conference.

Received 2 slides (F1-H&E, stain).

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Tall_Allen profile image
Tall_Allen

They should send all slides.

Congratulations! No evidence of cancer in those slides.

nvidia-ati profile image
nvidia-ati in reply to Tall_Allen

Thanks for your feedback! I did not understand the terminology of the pathologist's report. During my meeting with the second urologist, I plan to ask for an mpMRI. Does it make sense to request a MRI guided biopsy when I am healed from the TRUS biopsy?

I don't understand why the pathology lab did not send all the slides. I can contact them to send all remaining slides to Hopkins.

Tall_Allen profile image
Tall_Allen in reply to nvidia-ati

You have time for an mpMRI next year.

nvidia-ati profile image
nvidia-ati in reply to Tall_Allen

That's good to know. I'll also ask for a repeat PSA at that time.

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