Part Rant

[WIZARD6787]

There is more B12 in the liver than in other organs Guessing a weight/volume measurement. Someone who wishes they had what it takes to be a scientist came up with that the liver is a magical storage bank of B12. Divided the amount of B12 by the minimum daily requirement and came up with a foolish mathematical solution resulting in the myth that the body not only has years of supply but that the mythical storage bank needs to be replenished then maintained and that is all that needs to be done. See loading maintenance myth.

Google NIH Biochemistry water soluble vitamins.

This train of thought was born out of trying to find a way to correlate the data collected when injecting 1, 2 and 3 times a day with regards to my trials of different forms, combinations of forms and amounts of B12. I came to understand that the data I obtained is all but useless due to injecting only enough so that there were not adequate amounts in my bloodstream other than to heal slowly if at all is not applicable. A start and stop .

Pretty much who cares what the effect of inadequately supplying B12 in my bloodstream is with regards to different forms, combinations of forms and amounts of B12.

I now have to grieve the loss of not figuring it out in 3 years. I have done good work in grieving the pain and suffering caused by my buying into the physician’s brand as healers. It’s not a lie if enough people follow. My bad.

I am likely headed into a new line of inquiry which for me is still not focused on reading what others think is true, finding what works/experimenting or relying on experts. I will not rely on any assertion that the best I can do is wait for years or it definitely will happen if I just wait as there is no rational reason to believe that.

And yes I'm very angry about having to start a new line of inquiry. Hopefully this one will not take three years.I know I will not be trying to obtain ‘what works’ as what works is a personal value. I am looking for what works the best. That is what kept me going for 3 years.

Yes I am aware this is in part passive aggressive. I will not stay in that place. It is only a small part of my grieving process.

[Wwwdot]

Oh Wiz

It’s so emotional and painful searching for one’s health solution when there are no cheering crowds, no sponsors, insufficient research, and a clinical and medical climate of gaslighting.

You have achieved so much and now is the time to rest, reflect and regroup your thoughts for the next leg. Take care and I hope the support we can give you provides a balm to your anger and grief.

🤗🤗🤗🤗🤗

[WIZARD6787 in reply to Wwwdot]

Thank you for your reply!

It was a successful rant. I needed to do that to stay with my methodology which rationly leads to that I should now inject not less than 4 hours apart and set an alarm and inject in the night.

A indicator is the good effect of injecting if I happen to get up in the night.

My body works differently at night and it is possible that is the time I most need an injection so my body can heal.

It is a fact that peripheral neuropathy is more acute during the night. That was the case for me which I attributed to my body working differently and not any made up cause like I was more aware of it as that did not match my experience.

I took the break I needed. It is part of my analysis that if I crash in February and March as I have the last 10 years or so it will be a year before I will know that is likely in my past.

Looks like I will make my goal of not being sun deprived on the winter solstice!

I expect that when I increase the number of injections there will be at first an uptick then there will be an adjustment period. With the methylcobalamin I am now using there may be some experiences that could be seen as side effects and I may reduce amounts a bit to not have to deal with that. I will monitor those effects and if they do not resolve quickly than reevaluate.

[tomdickharry]

Please read 'the entero-hepatic circulation of vitamin B12'. The liver is not a store for B12. It needs what it has.

[WIZARD6787 in reply to tomdickharry]

Cool! Thank you. pubmed.ncbi.nlm.nih.gov/667...

[Rexz]

Hi Wizard, Most on this forum would agree that your rant is welcome here. I think all of us with PA have some sort of special permission slip to rant, cry, and be angry! Our journeys are a roller coaster of some ups and many downs and we never know which day brings what. So yes your rant is welcome here. 🙏Yes, the liver does store B12 and provides an almost constant trickle through the bile duct for recirculation. However this is useless to us. All of our useful B12 stores are in our blood serum. I never understood why NHS provides that B12 injections should be every three months. Yes, Hydroxocobalamin does last a bit longer in the blood than other forms of B12 but certainly not that long. I suspect they are thinking, like my original doctor here in the US, did that once liver stores are replenished that should carry you. But we know that's not true. I do have some research that B12 levels in the blood begin drop off after 4 days and after one week the B12 is halved. Then drops off further from there. Don't quote me on these numbers as they are notional from my memory. I will find those research papers and send to you as they are quite interesting. I must warn you though that I suck at organization and it may take a bit of time to find them.

Best wishes, Rexz

[WIZARD6787 in reply to Rexz]

Hey Rexz,

Thank you for your reply.

I have established that the effective length of time the B12 I inject at a effectiveness to promote healing is 4 to 6 hours. It would be cool f tenting was done on retention times with that in mind. Not likely.

[Wheat]

hello wizard, I agree with most of what you say. I know it is important that you need to grieve.

However, please remember it is not 'your bad' , apart from social/System inculcation, it you who is the victim, also you were not well enough to discern or question their truths.

Now you have come an incredibly long way. I applaud you. You should applaud yourself too.

[WIZARD6787 in reply to Wheat]

I know where the blame is for the restriction of EOD 1 mg. However I consider it a failure that it took me 3 years to discover the 4 to 6 hour effective length of time between injections. I fail all the time comes with doing things. 🙂

I do account for the degree of difficulty which was huge.

I have come a long way since September 01. Prior to that I was simply mitigating and doing a little bit better than those that support the EOD for everyone with disregard for symptoms and reaction to treatment other than to say it takes time. When something does not work as predicted starting it takes time or we are all different instead of accepting something is happening that you don't know about is common as is blaming the person who is not experiencing the prognosis given due to a failed protocol.

All that being said part of my grieving process will be going back over what I did and realizing I did good. It is a failing of intellect not of spirit. To try and jump to that without putting in the work does not work for me. Ask me how I know. 😀

Thank you for your kind words and encouragement. I do not happen to use the word applaud. I might tell myself "that was good work. "

I do a lot of celebrating. I just did by going down to a lake and watching the ducks.

There is a high degree of difficulty with B12 and the tribulations associated with it.