I noticed something.

[WIZARD6787]

I have done many trials of different amounts and forms of B12. I went over my notes and it could be that when I switched forms there were positive effects when I overlapped forms in that I still had both forms in my blood stream. Emphasis on could be.

I have decided to change my self-treating regiment to:

Inject .75 mg cyanocobalamin in the AM

Inject .75 mg methylcobalamin mid day

Inject .75 mg hydroxocobalamin PM

SL 6 mg adenosylcobalamin SL three times a day.

Other supplements to stay the same for now.

I understand that any effect will be evaluated subjectively. This is true now as the pain caused from peripheral neuropathy is so minor now I can not use it to evaluate. I could make a list of subjective symptoms. I choose not to, in part as I am sick of all this work. Making a list of subjective symptoms is still a subjective evaluation.

I could just stay with my current regiment with the assumption if it worked for the peripheral neuropathy it will work for other symptoms. Having changed how I see my "B12 Deficiency" as life long and a transcobalamin issue staying with the current regiment is not the best bet.

[Wheat]

hello Wizard6787, I admire your attitude. Also appreciate your sharing this. I wish you further success with your new self treatment regimen.

[WIZARD6787 in reply to Wheat]

Thank you very much. I appreciate and gain lots of insight from people who share here.

[B12life]

love your style of experimentation and then team spirit of sharing it. Though I feel I have stabilized some, I feel I could use some finessing of my regiment.

For my journey, these things resolved first:

heart palpitations, nerve and back pain resolved and then progressively the fatigue kept getting better gradually over the last 2.5 years.

The biggest thing which still is a challenge is the brain fog. I got 65% there with the b12 but hit a wall and then started taking b multi and high dosing b1. It's the b1 that got me farther with brainfog. Amazing; however, I still feel like I could do better by trying your approach.

I also wonder if my limits to exercise might be helped. If I do very long challenging stents of exercise, I get depleted. To get past that, I would double my dose of b12 which definately made a difference in preventing the depletion.

I stopped doing 2mg/day because of acne and backed down to 1mg /day IM again. I'm not exercising like I used to so that works for now but want to go back up in does.

I think your style of injections throughout the day vs one per day is the best as the body is more likely to retain rather than just dump the b12 that way.

All in all, people think I do the b12 for exercise. NO. I was active before the b12 and wanted to go back to being active. I find light activity helps process the b12. In addition being very active helps mental clarity and my desire is not to get a medal or compete but to prevent injuries and reach the fountain of youth... well not really but just stay healthy. For those that don't want to take it this far with exercise, I get it. Honestly I do 1-2 hours a day when I'm active of either walking or biking and I don't do it necessarily competitively. I started out doing 15 min and gradually worked at it, but only after 1 year of daily injections during which I could barely do minimal tasks.

I did find some b12 that was in higher concentration which worked well, esp dosing twice a day; however, I believe it was causing or exacerbating the acne.

Keep up the work and keep posting what works for you, it's inspiring, interesting and helpful!! Inspiring in that I really shouldn't settle on what I am doing, I should strive to get the ultimate treatment that works for me.

Cheers to everyone here and their individual journey and contributions here. PAS, This forum and all it's members are my family!

[WIZARD6787]

Thank you for sharing. Critical thinking is what is most important when I decide to try a trial.

I found that Betine TMG along with my other supplementation eliminated my acne. 2 g am and PM. It is used for performance at that level. I buy it from Peakssupps.