What causes small nodules to form in lymph nodes

[Madmolly]

Nodules

[Irisisme]

Hello Madmolly,I think we need more info. Is the nodule just under the skin? Or is this something that was seen in a CT scan report?

If under the skin it could indicate an infection in the gland.

Iris x

[Madmolly in reply to Irisisme]

Iris apologies for not getting back sooner a lot going on with mothers day granddaughter setting up Alexa. I was on the ICON trial which finished this month, 15 months in total had op right ovary, peritoneum , omentum, 3 nodules etc and was ned. However at last scan oncologist said very tiny nodules inside 3 lymph nodes did not know what it was have booked another scan for May. Last dose of avastin 3 weeks ago I just wondered had anyone ever been told similar before

[Irisisme in reply to Madmolly]

Hi again Madmolly, I hope you had a lovely Mother’s Day 💐

Ok. This is the worst bit of all our journeys - the waiting and not knowing. This really could be an infection, or simply a benign ‘lump’, and not your cancer- but there’s nothing certain about it.

I have similar and mine is judged to be progressive disease but without a biopsy they can’t really tell, it depends on your own history - and your oncologist is going to be reluctant to disturb it with a biopsy at a guess. Hopefully another scan will be more revealing.

Maybe you could contact him/her again via the secretary and explain that you’re really worried and want to at least know what the possibilities are right now. Your oncologist must have some thoughts on the matter but is unlikely to want to commit to anything at this stage.

My thoughts go out to you as it’s horrible when you’re left wondering but there is really nothing else any of us could tell you about this - I don’t think so anyway.

Maybe you could contact admin for help?

Sending hugs,

Iris 🤗🤗

[Madmolly in reply to Irisisme]

Hi Irisisme, I think your right by saying onc does not want to commit. My ca 125 has gone up to 44, but you are left wondering what next stage would be. Although I have just this minute just finished trial I have not had the chance to enjoy being ned as constant pain due to avastin although the are sending me to rheumatoligistTo see if pain connected to arthritis, but have the feeling it's raising its ugly head again. Will have to wait and see

[Irisisme in reply to Madmolly]

Ah, the joint pains! Yep, me too - I see a rheumatologist and am now on an anti inflammatory (Celecoxib) and have had to rely on Cocodamol since my first line chemo and Avastin.

I’ve never got any health professional to admit that Avastin (or any chemo drug) causes the joint pain but too many of us have it to be coincidence.

Good Luck with the rheumatologist,

Iris xx

[Madmolly in reply to Irisisme]

Once again was replying and it disappeared. My onc has stated taxol and avastin both cause pain so now that I'm off meds after 15 months will just have to see how it pans out. I have been keeping busy clearing out cupboards and am amazed at the amount of junk I have collected. So loads of bags for the charity shop. I will keep you posted and hope you are doing OK.

[Irisisme in reply to Madmolly]

👍😁 well done for having a clear out! I look forward to hearing what your rheumatologist says xx

[Madmolly in reply to Irisisme]

Like yourself I like to know everything that's going on. I'm on last lap of weaning me off prednisone down to 2.5m. Want to know if extreme pain in ankle is arthritis or not. However good to have a little sunshine today took a drive to Loch Lomond only 5 mins away. Was it nice in Colchester

[Madmolly in reply to Irisisme]

Have been to rheumatologist and yes I have osteoarthritis in hip, knees and right ankle she has put me o n 250m of naproxen but don't know is this would account for ca125 being at 44 considering they are saying I'm ned. Also said naproxen can be increased if it is not dealing with pain. Don't k ow how long avastin takes to leave the body. I know I've been booked in for another scan no date through yet, probably to monitor if growth in nodules in my lymph nodes. That's my 15 months on trials up hoping for some respite. Trying to remain positive. Hope you are good🌞

[Irisisme in reply to Madmolly]

Hi Madmolly,Sorry to hear that you have a number of joints affected by osteoarthritis, maybe that inflammation would bump up your CA125 result.

Please, if your rheumatologist says the Naproxen can be increased don’t be brave and try to put up with more pain than you need to.

I have thought about whether I should say anything about NED but as you do like to know everything I will tell you what I’ve learned this year.

Firstly, ask your oncologist what is meant by NED. I’ve recently learned that my “clear scans” simply meant that the lesions were less than 1cm, not that there were none at all! The clear scans puzzled me because I as told that there was a massive ‘seeding’ around my bowel which chemo wasn’t going to completely eradicate. I was pleased about having clear scans but the radiologists weren’t reporting anything under 1cm apparently, so the report was somewhat misleading.

My last scan report said that a lesion was now 2.7cm and it was 1cm on the last scan - but the report from that last scan said there was nothing!

Worrying, isn’t it? Certainly worth enquiring. I hope I haven’t given you more worries but I think we should be told this sort of thing.

I wish you a pain free future, Madmolly,

And send virtual hugs.

Iris🤗🤗🤗

[Madmolly in reply to Irisisme]

That is very interesting to know. I obviously k ow there will be cancer cells floating about but unaware of lesions being under a certain size not being.counted. Today I have been informed that my oncologist wants to tel me on Thursday morning I do not know if this is with regards to a follow up from the rheumotologist report but I will raise this with her. Thanks for that information. I am continuing to take heavy night sweats which I thought were due to meds that I've since stopped so that's another query I have. Thanks for imparting this info it all helps I am still getting pain in k eesnot quite so bad but looks like I will have to increase the naproxen dose. What are they now saying about your lesion being 2.7. Best of luck with outcome.

[Irisisme in reply to Madmolly]

Oh, I’m on 3rd line Paclitaxel now, I had my fifth infusion last Friday. I’m doing ok, the hair was falling so I did the ‘chemo shave’. Sundays are my only bad days. Paclitaxel should work for me still 🤞🤞😁🤗❤️

[Madmolly in reply to Irisisme]

Glad to hear you are doing OK. Was not receiving any posts for last 9 days they have explained how to fix it. Don't know if I'll manage

[Cheryl4677 in reply to Madmolly]

Hi Molly. I was on the ICON9 trial but it was stopped in Aug 2020 after progression was noted on CT scan. I don’t think I’ve ever been NED but there were new lymph nodes and I was persistently anaemic despite several transfusions and dose reductions. My CA125 was rising so carbo/Caelyx course was the next step. Unfortunately not as effective as first thought and now looking at weekly Taxol. Hoping everything at least remains stable for you.Mother’s Day was very different from previous years. My daughters and grandchildren made brief visits and gave me some lovely gifts and flowers to brighten up my house and my spirits! It’s hard not to worry but hope you had a nice day. Best wishes. Cheryl x

[Madmolly in reply to Cheryl4677]

Hi Cheryl I was in the middle of relying to you and don't know where it went, I'm pretty hopeless when it comes to things like this. Dis get caught up with mothers day lovely to see my grandchildren fair cheered me up. Having had couple replies looks like your right and could be progressive but onc not wanting to commit at this point to see what scan through up. It's not knowing what the next stage will be as having just finished trials was looking for some respite but it's as most folk say it's all about the waiting game. I had lovely flowers and chocs for M D but heard sugar was bad for cancer cells would you know if this is correct or not. I was never really sweet toothed

[Cheryl4677 in reply to Madmolly]

I’m glad it’s not just me who seems to lose posts! Not very tech savvy but don’t really want to be. Necessity in this day and age though. I call on my son-in-law who is thankfully very knowledgeable about computers etc when I struggle. Our computer is very old so extremely slow at times. Just like us really. Not installed with the latest upgrade! Sugar always seems to be considered to be the devil! Maybe just bad press. I just eat what I fancy in moderation. Especially when the appetite isn’t always good. Still have chocolates in my fridge from Christmas. Enjoy. X

[Madmolly in reply to Cheryl4677]

Thanks Cheryl, I know we get varying press basically about everything and I would have thought if it was significant my onc would have said something