Cediranib

[Cebacob]

Hi Ladies - I am from Canada - haven’t found as good of a site for OV cancer here! I have OV cancer stage 3 - now in my 3rd occurrence since being diagnosed 2 years ago. It’s been a tough journey as you all know! I have just started a trial here in Canada - I am receiving the Cediranib only. My question for anyone out there that has taken Cediranib is: A few days after starting it I got a bad back pain on the right side just above my waist - I have had a few massages but it hasn’t helped - has anyone else experienced this? And how have others felt being on Cediranib?

[LittleMissStubborn]

Hi, I've been on Cediranib and Olaparib since November so it is sometimes difficult to know which drug is causing the worst of the side effects. From the start I have had what I describe as 'bone ache' particularly in my back and I say bone ache as massaging doesn't relieve it. When I mention this to my consultant he says that's the cediranib. The worst side effect was the diarrhea but I had a dose reduction so I have 2 cediranib free days per week and that has solved it. Apart from that it's ok. What does your oncologist say about your pain? I hope you can find out if it is the cediranib or not and at least stop the worry. X

[Cebacob in reply to LittleMissStubborn]

Thank you!! I have had some really rough days since going on Cediranib.... today the oncologist thought it best to take me off for a week and then start on a lower dose ... so hope this helps! What other symptoms have you had? Have you had good results so far? I’ve had lots of diarrhea and some vomiting and lots of nausea.... and big problems regulating my blood pressure... did your symptoms start right away? Get worse???

Thanks so much for replying and sharing your story with me!

[LittleMissStubborn in reply to Cebacob]

Hi, we all react differently to these drugs and I'm on Cediranib with Olaparib. Yes, the side effects started straight away and got steadily worse until I had the dosage of cediranib reduced. I then felt better immediately apart from the bone ache. I find exercise is the best thing for the bone ache as I fear I'll cease up otherwise! Hopefully you will feel some relief when you start your reduced dose. I've had 2 scans: the first showed a 15% reduction in all areas and the most recent one showed a reduction in one area and stability everywhere else. The treatment is working for me.

I really hope you take well to the reduced dose and that it starts to work well for you. X

[Hidden]

Hi I cant advise on Cediranib but wanted to say hi and welcome. I was diagnosed in May 2018 stage 4 and am also on my 3rd recurrence.

There is a wealth of knowledge on this forum and a host of lovely ladies always ready to share their experiences, I don't know how I would have got through the last couple of years without their support. x

[Katmal-UK]

Hi, I trialled cederanib back in 2012 for a first recurrence. I cant say it didnt work because I believe I recurred due to the shock of mt father dying. I did find it affected my bowel movements but other than that the trial went well. I had a pain like you are experiencing but not on cedranib and my dr said id coughed and cracked a rib. I hope the trial goes well for you xx

[lesleysage]

Hi, even though not in UK, you are most welcome to contact the Ovacome support team who maybe able to help you? The link is: ovacome.org.uk/support-line

Many of us here have used their Freephone but you'll see you can email or Skype (I think).

Good luck with your treatment and side effects; warm wishes, L x