Has anyone had more than 10 treatments on taxol carboplatin

[Tennisgrl]

[Meryl]

Hi there

Over the last 4 years I've had 2 full courses of carboplatin/taxol and one on carboplatin /gemcitobin that's 18 in all. The last finished this Easter. The first two my CA was in single figures on completion and this time it was 63. No lasting side effects. I've also had 2 courses of other chemo the best result was on caelyx. I'm not sure if you have a particular reason for asking the questions but if I can help please say. Good wishes. Meryl

[Tennisgrl in reply to Meryl]

Thank you for your reply my cancer is different but my drugs are the same I feel better knowing other people have tolerated these drugs for as long wishing you the best. I have been scared to talk to people. But I am so glad I found your group

[harley]

Hi There,

Since June 2013, I have had 6 treatments of Carbo/Taxol, then recurrence in 2012 only managed 2 carbo/taxol but continued with taxol, this year had 3 taxol and then 3 with cisplatin/taxol - glad to be finished and get life back to normal for a bit - OR A LONG TIME.!

Joanna XXX

[Hidden]

Just wondering if you asking about 10 cycles in one regimen which seems unusual as 6 seems to be standard practice. Is it your first line and do you know if the dose is reduced per cycle and what effect has 10 had on your condition. Carboplatin is often used either as single agent or commonly combined with taxol, caelyx, gemcitibine. Love Paul xx

[Tennisgrl in reply to Hidden]

I have stage 4 rectal mucosal melanoma first I had yervoy then 6 weeks of radiation and now 15 treatments of taxol carboplatin I had the last treatment every 3 weeks and now every 6 weeks . I had hair loss and only neuropathy in my right foot and was curious if anyone else did this much chemo I am now stable but it just seemed like a lot thanks for your reply

[aliannie]

Hi, I had 18 weeks of carboplatin and paclitaxel, with no break in between as part of the icon 8 trial. I finished treatment Dec 12, and after scan in Jan 13, I have no evidence of disease!!!

Alison xx

[Tennisgrl in reply to aliannie]

So happy for you. I have evidence but stable disease 18 weeks would be 6 times? I have had 15 doses iit seems like a lot but I am stable so I just wanted to see if anyone else had this many thanks for the reply

[aliannie in reply to Tennisgrl]

Thank you, I went for treatment one day a week for 18 weeks and each time I had a half hour of paclitaxel and one hour of carboplatin,

Xx

[thehusband]

My wife had 6 x taxol/carbo in 2011. Later 4 x taxol in the same year and later still in 2011/2012 she had 8 x gem/carbo. So a total of 10 Taxol & 14 Carbo overall. Good luck.

[Tennisgrl in reply to thehusband]

Thanks for the reply is your wife also stage4?

[thehusband in reply to Tennisgrl]

Diagnosed 3c, and i think you always keep the same 'diagnostic level', though in reality now unfortunately she is stage 4 plus. The best 'reaction' she had was with gem/carbo, but as you know everyone is different and what is good for one may not be good for someone else, though gem/carbo tends (as far as i can tell) to often work well, albeit quite a demanding regime.

[Tennisgrl in reply to thehusband]

Thanks for a reply I have faith in my oncologist. I actually think she is brilliant but my cancer is do rear and success on taxol/carboplatin has been fair at best

[Hidden]

Hi Tennisgrl,

My guess is because you have a different cancer to the people on this forum that your treatment would be different ...but I have had carbo/taxol twice i.e. two courses of six..(twelve in

all) best wishes love x G x

[Tennisgrl in reply to Hidden]

They call it being a zebra put it is great to talk to someone who has taken these drugs all the best to you also

[Hidden in reply to Tennisgrl]

Hi Tennisgrl,

I don't know what time it is where you live, but it is now 1:20am here ...so I should be in bed...it's comforting to know that other people are awake too.

Sending you best wishes love x G x

[Hidden]

Like a lot of people here, you've been through the mill. I didn't know it could be given once a week for 18 weeks. Presumably, the weekly dose is reduced? I don't know answers but I send you my heartfelt good wishes. X

[Hidden in reply to Hidden]

I am currently doing the ICON8 clinical trial as mentioned by aliannie and have just had my 5th weekly treatment of 18. Yes, you get the same amount of the carboplatin and paclitaxel over the 18 weeks, but instead of the big dose once every 3 weeks you get a smaller dose every week. The theory is that the side effects are less by giving the smaller dose, and you have less time without the drugs in your system so less time for the cancer to recover between doses.

For me the only side effects I am getting so far is the hair loss (I decided not to opt for the cold cap) and constipation, and I actually feel much better than before I started chemo - the cancer seems to be reducing quite quickly already and I was diagnosed at stage 3c

[Bliney]

I had eight cycles of carbo/taxol. I had six cycles before the debulking surgery and the two cycles after the surgery. Towards the end I was gettinf a littke chemoed out - platlets and neutraphil low so had to take repeated injections of filgrastim.