Ongoing flare - naproxen doesn’t work!: Hello all, I’m... - NRAS

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Ongoing flare - naproxen doesn’t work!

JoH80 profile image
43 Replies

Hello all, I’m writing just to get this off my chest at the end of a very painful day! I’ve had an ongoing flare for several months and have just been prescribed naproxen which doesn’t seem to work at all. I’ve been taking it for two days twice a day and The pain is worse each day, I can’t sleep in the morning and have to get up I’m in such agony especially in my shoulders. I was using ibuprofen before this which I actually felt less pain on but had wrongly thought naproxen would be the silver bullet until I start on imraldi in the next few weeks. Can it be the case that ibuprofen works better for me than naproxen?

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JoH80
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43 Replies
Lolabridge profile image
Lolabridge

It’s possible although I think it’s more likely that your flare is getting worse. I see from a previous post that you have tapered your steroids down and that you were on Sulphasalazine and Hydroxychlorine. If you’re no longer on any of these then I think that is likely to be the cause of your problems.

JoH80 profile image
JoH80 in reply toLolabridge

Ok thanks. Damn it...

DianeMH profile image
DianeMH

I feel for you JoH80. Naproxen doesn’t work for me either. Like you I find Ibuprofen worked for me better.

JoH80 profile image
JoH80 in reply toDianeMH

I’m going to swap back to ibuprofen today. I had to take two lots of paracetamol during the night to sleep which at least took the edge off it! Thanks for sharing your experience!

mhlmom profile image
mhlmom

To get some sleep when it’s bad, I have Tramadol which the GP prescribed. I only take it occasionally but it works well to give me a good 6 hours. If I can sleep, i can cope better during the day.

JoH80 profile image
JoH80 in reply tomhlmom

I’ll investigate

Eiram50 profile image
Eiram50

I feel for you!

I can remember trying naproxen, way back at the very beginning and it did nothing.

The only anti inflammatory that has made any significant difference to me is arcoxia. It’s the one tablet, if I don’t take, I absolutely know about it.

Maybe have another chat with your GP / rhuemy. You shouldn’t have to suffer this way.

Wishing you better times, soon x

JoH80 profile image
JoH80 in reply toEiram50

Will give them a bell and thanks for the good wishes!

Can you put your steroids up?

I take an anti-inflams especially for RA called Etoricoxib 60mg per day. Its really good.

JoH80 profile image
JoH80 in reply to

I’m tapering steroids to finish in Sept in anticipation of starting this biologic. I’ve been on steroids for ages and keen for a break if possible

in reply toJoH80

That doesn't make sense to me. The biologic could take 12 weeks to work.

Moog73 profile image
Moog73 in reply to

Morning kikidee, I was gonna post the same thing.

After coming off steroids way back, I feel this is the one tablet I wouldn't want to drop.

I was on 90mg now down to 60mg.

Have a good day all😀

in reply toMoog73

Hi moog

Yes I was on 90mg too but the gp says because of the risk with anti - inflams and coronary heart disease he said everyone has been put down to 60mg.

When I hurt my back last Dec I was given 30mg tablets so I was able to add that in for a few weeks.

Moog73 profile image
Moog73 in reply to

I get get lots of ulcers from all the different medicines 💊, not sure which ones cause this.

in reply toMoog73

Oh no poor you.

I don’t get any relief at all from painkillers during a flare. Over the years I’ve had high dose (as in 800mg 3 times a day on GP’s advice) ibuprofen, naproxen, diclofenac, codeine, prescription strength cocodamol, and even tramadol, although having had that a couple of times post operatively, I don’t respond to tramadol for anything tbh. The only thing that’s ever provided any relief at all during a flare is pred, and the combination of DMARDs I’m on right now, although that’s to a lesser degree than the pred was achieving, even if I hated the way it made me feel generally. If you’re literally only taking NSAIDs in the middle of a bad flare, I don’t think you’re likely to find much relief. Did they tell you to stop anything/everything else you were on prior to starting the imraldi? I’m still new to arthritis, but from what I do know, that would seem a little bit daft under the circumstances.

JoH80 profile image
JoH80 in reply to

I’ll be stopping hydroxychloroquine and the steroids once I begin with imraldi and obviously trying to be very optimistic that this will get things back under control 😁

loglegmomma profile image
loglegmomma in reply toJoH80

My husband has found that hydroxychloroquine gives him terrible muscle aches & spasms, so you may feel better without it.

JoH80 profile image
JoH80 in reply tologlegmomma

It has really been worse than useless for me so I’m up for any changes right now 😁

Naproxen never touched me at all. Worth talking through your frustration with your team. Not all drugs work for everybody and I tend to always check how 'quick' the response will be to GP scripts and if no change go back and try something else. This is not the same to RA drugs as they have a longer time frame.

Brushwork profile image
Brushwork

Naproxen has an accumulative effect, keep taking it for a week, by then it should be effective, if not you will know you need something else.

JoH80 profile image
JoH80 in reply toBrushwork

Thanks for the info, I’ll persevere a few more days just to see

-Mii profile image
-Mii

Sadly only steroid injections or a course of steroids seem to help me and my friends with RA.

Rashford20 profile image
Rashford20 in reply to-Mii

Steroid injections are like going on a holiday

JoH80 profile image
JoH80 in reply toRashford20

I had one when I was first diagnosed and it was incredible but I had another in December and it did nothing! I was gutted! I was expecting that holiday 😁

Suereeves profile image
Suereeves

I’ve had RA for many’s years and take all sorts of meds. If when I have a really bad flare I always always find 2 anadin extra soluble in warm wAter is the best for quick pain releif. Also nurofen plus are the best when the agony builds . I’m on rituximab which has really helped me. Sounds like you need your steroids as well to calm things for now . Hope this helps

Anniebl24 profile image
Anniebl24

I would suggest etoricoxib. Two people have already suggested it above. I find it excellent.

in reply toAnniebl24

My Gp won’t prescribe Etoricoxib even though I can’t take naproxen or ibuprofen

in reply to

It's an anti inflamm so if you can't take naproxen maybe that's why. Why can't you take naproxen?

in reply to

It gives me tinnitus 🙄 I was given Etoricoxib in hospital but none will prescribe it now

in reply to

Maybe it would do the same. Does the tinnitus go away when you stopped it?

in reply to

It did go away about 3 weeks after my last tablet but was told not to take it again

in reply to

Glad it went away 👍

Cfor profile image
Cfor

I've been on Methotrexate for years and also 5mg of prednisone every day. This usually keeps the flares at bay. If I do get a flare I Dose with prednisone usually 25 mg and lower by 5 mg per day.

JoH80 profile image
JoH80 in reply toCfor

That’s interesting I hadn’t realised that’s an option

in reply toCfor

Cfor

Generally if you get flares it means your treatment isn't working anymore and it's time for a change. No drug seems to stick with me I've been on at least 10 so far.

medway-lady profile image
medway-lady

I'm not allowed NSAIDS or Ibufren as allergic to it. But I had Shingles last year and it was hot burning agony over small of back down to knee and back up to groin. Pregabalin was like a magic bullet. Worked a treat but had to be tapered which was no big deal could be worth asking about that.

in reply tomedway-lady

My dad was prescribed amitriptyline for his shingles pain. He said he didn't know if it stopped the pain or made him not care 😉

medway-lady profile image
medway-lady in reply to

Could be lol x

Elmo333 profile image
Elmo333

I thought naproxen would be stronger but my gp told me that they just prescribe naproxen because it is cheaper for the NHS than ibuprofen. I truly hope your flare subsides.

in reply toElmo333

Brufen can't be taken long term.

Chrissycl profile image
Chrissycl

Yes I have been on both but ibuprofen suited me better. I still take my other meds and also have swappped from Enbrel injections to baricitinib tablets but still need to take ibuprofen

Winnie53 profile image
Winnie53

I take Etodolac 600mg slow release anti-inflammatory. There is an accumulative effect with this as there is with Naproxen. No quick fixes unfortunately.

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