Antidepressants and Biologics?? : Hey guys, first post... - NRAS

NRAS

37,219 members46,055 posts

Antidepressants and Biologics??

Mjkruger profile image
1 Reply

Hey guys, first post here. Good to know there’s a community for this stuff as I’m sure if you’ve all had to deal with a ton of stuff over the last little while. I’m wondering if anyone has had any problems getting their antidepressants to work while they’ve been on a biologic? I went on Avanza (antidepressants) after starting Golimumab (biologic ) and prednisolone and everything was going pretty good until I had an allergic reaction to an antibiotic (Keflex) that caused temporary paralysis in my body. Now after two months it seems like my antidepressants have stopped working and started to interact with my other drugs negatively, has anyone else had anything like this? The doctors thought it was because of the prednisolone (I would go into a negative spin after every subsequent pill), but I’ve stopped that now (and added in another antidepressant) and seen no improvement in mental health (after seeing so much improvement initially). Has anyone else had their mood drastically impacted by their drug interactions? Or felt especially depressed after taking Humira or Simponi?

Written by
Mjkruger profile image
Mjkruger
To view profiles and participate in discussions please or .
Read more about...
1 Reply
oldtimer profile image
oldtimer

It's very common to become depressed after having a diagnosis of a long term condition. Especially if you had a temporary paralysis - I think that would upset the most level-headed person! Some of the problems can best be helped with talking therapies with a therapist - have you any access to these?

Sometimes too, an initial improvement on medication can be due to the placebo response (we expect to improve on medication) only for that to fade with time.

But you do need to be guided by your medical team as to the way forward with medication.

Not what you're looking for?

You may also like...

Biologics and methotrexate

My rhumy doctor would like to get approval for me to have rituximab after Humaira stopped working,...
Ozzy profile image

Biologics?

I am new here and I have the opportunity to go on these biologic drugs by injection. It is just...
Brede profile image

Bronchiectasis and biologics

I am new here. I have both RA and Ankylosing Spondilitis with bronchiectasis and am being...
Shonkie profile image

Results of biologics

So I am just wondering what’s the best anyone can expect to be on biologics? I am in my 30’s and...

Biologics

Hi everyone I phoned the nurse help line before Easter and found they are going to put me on the...
Akaka profile image

Moderation team

See all
Nicola-NRAS profile image
Nicola-NRASAdministrator
KateL-NRAS profile image
KateL-NRASAdministrator
Plankten profile image
PlanktenAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.