Two of the most promising nash drugs in development that have the same mechanism of action. Seems to be the promising drugs for reducing fat in the liver. Also significant lower of lipids (Apo-B, trigylcerides, LDL, etc).
Mgl-3196 about to begin Phase 3 study and vk2809 phase 2-b.
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jpin22
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Madrigal has some very promising data with mgl-3196 as does Viking with their vk2809. Interestingly, both are thyroid hormone regulators aimed at steatosis and lipid metabolism. Hopefully their studies hold up as we expect the eventual treatment to be a cocktail with several very targeted molecules and these are exploring one of the key hormone systems.
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