Stem Cells in Columbia

[Armyman]

I was referred to a Stem Cell facility in Columbia called Infinity Regenerative Medicine. They use MSC cells from the Whartons Jelly of the umbilical cord. They administer the cells combination intravenously & intranasal for $15.5K or intrathecal $15.5K. The website has a before & after testimonial from a Michele that shows amazing results. I'd be interested in hearing from anyone that has heard about Infinity or has experienced stem cell treatment elsewhere.

[Bolt_Upright]

I looked at their web site. They don't say what their procedure is. If they are not injecting stem cells into your brain it is probably not going to do anything.

[jeffreyn in reply to Bolt_Upright]

Bolt, does this mean that you think that Hope Biosciences and Uni of Texas (with their collaborator Michael J Fox Foundation) are probably wasting their time with their IV-based MSCs-for-PD clinical trials?

clinicaltrials.gov/ct2/resu...

[Bolt_Upright in reply to jeffreyn]

I thought Hope was getting the stem cells into the brain.

[jeffreyn in reply to Bolt_Upright]

Not directly.

[jeffreyn in reply to jeffreyn]

As @7springshollow put it a couple of weeks ago: "During an IV infusion it is estimated that 20% of the cells end up in the brain. Hope bioscience is using very high numbers of stem cells and multiple infusions to assure an adequate number of stem cells end up in the brain to be therapeutic ."

[Bolt_Upright in reply to jeffreyn]

Interesting. Thanks for sharing.

[jeffreyn in reply to Bolt_Upright]

Something I posted on another thread may also be of interest.

From the Hope Biosciences website:

"The mechanism of action for mesenchymal stem cells have been found to include tissue repair, activation suppression of T and B lymphocytes, release of anti-inflammatory, anti-apoptotic molecules, and changes to the differentiation, maturation, and function of dendritic cells, all of which may aid in correcting immune system dysfunction that plays an important role in the development of Parkinson's disease."

The mechanism of action of IPSC (and ESC) derived dopamine neurons is via the direct replacement of dopamine neurons lost from the substantia nigra.

IPSC: induced pluripotent stem cell

ESC: embryonic stem cell

[Boscoejean]

clinical trials involving stem cells in the United States

clinicaltrials.gov/ct2/resu...

[Manypony]

I’m pretty sure that’s the procedure I had at NaturesCure in Seattle. No noticeable effect.

[amykp]

Unless it is a clinical trial and FREE--it is a scam. There is no approved, available stem cell treatment for PD...yet, and that is true world-wide.

The ability to turn random cells into baby dopamine-producing neurons is still laboratory medicine. Also, those cells have to be injected into the part of the brain where they belong (there might be one exception to that, I think in texas? but again, it is FREE...or they pay you.)

Just randomly injecting "stem cells" into your blood (stem cells for what? Blood? Bone? Macrophages?) (to settle where? Your liver? Remember you have a barrier to keep things from getting from your blood to your brain) how is that going to help replenish the dying dopamine-neurons in your substantia nigra? And even if they make dopamine (unlikely) there is concern that putting cells in the wrong spot can do more harm than good. What will regulate the production?

Think about it--if a stem cell "cure" for PD was as easy as throwing a bundle of money at a clinic somewhere, NO rich people would have it anymore. You think Michael J. Fox would still have it, or Muhammad Ali would've died of it?

But there is hope. They are working on it. You can join a clinical trial, possibly. Just don't pay anyone anything.

[Baron1]

Good Evening,

My reply maybe a bit late to the topic, but have you looked at the therapy from Trinity Clinic Fukuoka in Japan involving 10 intravenously administered doses of 200 million autologous adipose tissue-derived Mesenchymal Stem Cells over two hours. This is repeated every fortnight until 10 treatments are completed. In order to reduce the risk of graft-versus-host disease, the patient’s own stem cells are used.

The stem cells are extracted from patients’ own (autologous) fat, or adipose, tissue. Following extraction, the cells are expanded in the laboratory until they reach high numbers, and injected back into patients’ blood.

This is the correct way to use stem cells, over several coarses of treatment, not just one or two as most clinics use.

Maybe this the avenue you can take.

[WinnieThePoo in reply to Baron1]

I take it you get good commission for repeating the same post a dozen times

[Baron1 in reply to WinnieThePoo]

Good Morning,

I was posting to the threads that had the most recent questions and statements about "Stem Cells". I live in Australia, what would I have to do with Clinics overseas; especially in Japan?

Really, is this what you get out of my post?

I posted it to five stem cell discussion topics, not twelve. So please do not exaggerate.

Clearly you have a chip on your shoulder about something.

Sorry for trying support those who maybe interested in stem cells.