Heat shock proteins and reduction in protein aggregation and inflammation

Heat shock proteins (Hsp) are a key player to maintain protein homeostasis and folding in neurodegenerative diseases (NDDs) such as Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), etc. Hsp are associated with NDs via induction of proper folding of toxic misfolded protein. AD is the

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[amykp]

Yes, I believe HSP's are another tool in the toolbox against PD, but you pretty much have to have access to a sauna or hot tub. The way I understand it, you really have to get HOT and stay that way, for like 20 minutes or so. That's hard to achieve in a tub or shower.

If you are interested, watch some of the videos by Rhonda Patrick. She's great. The bottom line seems to be that physical stress is good for you: heat, cold, exercise, fasting...they are all differentish sides of a similar coin, I think.

Because we are lucky enough to live in Florida, we DO have a hot tub, because we have a pool. In the fall and winter I keep it at 105-106 degrees and try to use it most nights. (Submerged, up to my neck, until my pulse goes to about 110) Then I do cold shock, in the pool. But as I said, I'm lucky to live in FL.

[Hidden in reply to amykp]

It applies to cold as well which is easier to implement at home. I should of added this to previous posts about sauna but wanted to emphasize the protein clearing affect.

[amykp in reply to Hidden]

Ha, cold yes, but ugh... I have to steel myself to jump into the 70-ish degree pool (which is only considered cold AFTER the hot tub.)

I have a friend who does the ice bath thing, and the thought of it just leaves me speechless.

BTW, another minor but interesting thing: hot, then cold (eg sauna then pool) is a soporific like nothing else. I can't do it during the day or I have to take an instant nap. But it's great at bedtime.

[Hidden in reply to amykp]

I need soporific! Thank you for this idea!

[Hidden]

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