I am taking a break from Magnesium. You are welcome to change my mind.

[Bolt_Upright]

I have not been diagnosed with PD. I have REM Sleep Behavior Disorder.

I just have too many supplements on my list and feel I need to cut a player: pdprotocols.atwebpages.com/...

The evidence I see for Magnesium seems thin and not specific to PD.

I have a high school degree and am error prone, so don't take your lead from me. I just wanted to share my thoughts on this.

Bolt

[LAJ12345]

Everything in balance! Why not just reduce it to a couple of times a week at first rather than going cold turkey? It’s definitely something you need so make sure you are getting enough in food.

[Bolt_Upright in reply to LAJ12345]

That's a good idea. I have been thinking about identifying "every day" supplements and "once or twice a week" supplements.

Also, I have this idea that I should take the supplements I gave up on, once a week, so I can use them up. Except for the ones I think were counterproductive at all. Probably not genius level thinking

[2bats]

Magnesium is the only supplement that I know works for me! If I don’t take it I do get cramp. If you don’t take it and don’t get cramp maybe you’re not deficient - But the majority of the population is magnesium deficient…

[Dap1948]

After 12 years, I have had to stop magnesium. Even a tiny dose was giving me awful over dose symptoms... panic attacks in the night, all my muscles going rigid, extra shaking. Since I’ve stopped the magnesium, the symptoms have stopped, so I’m hoping I’ve found the culprit. It seems you can have too much of a good thing!

[eschneid in reply to Dap1948]

Worse tremors or a different kind of shaking?

[Dap1948 in reply to eschneid]

An all over shaking. My Parkinson’s tremors are light in comparison. I kept going very hot and felt nauseous. It went on for hours. I had seven ghastly nights like that until I suspected the magnesium. Yet 12 years earlier, magnesium had calmed me and relaxed my muscles and now it was doing the opposite.

[eschneid in reply to Dap1948]

Sorry for the torture and glad you found the cause. My son mentioned his dreams are crazy when he takes magnesium at night. I take mine early in day to prevent 🏀 leg cramps.

Only thing I would suggest is to take it in the morning and a smaller dose & maybe you'll be surprised.

[LAJ12345 in reply to Dap1948]

You’ve probably filled up all your reserves and they overflowed. But if you stop they might eventually run down again. Perhaps you should just take it a few days every now and then. The same theory applied to B1 remember. Overdo it, stop a few days then halve it and start again. Seems logical

[1953bullard]

I’m going to cut way down on mine, I have every sign of overdoselivestrong.com/article/3790...

[nuttywally]

Precisely. 10 years REM SDO, no Parkinson's. I think melatonin is somewhat preventive. I just had a datscan that showed normal dopamine receptors - in other words no parkinsons. If you have medicare, it's covered. I know I am not entirely out of the woods, but it is a huge relief after years of anxiety. I take mag-l-threonate at night, and after reading comments will shift it to daytime. I also have been avoiding clonazapan like crazy, though a long talk with my sleep doctor today is leaving me more open to it. I also am taking spirulina, and phosaphatidyl serine, niacin, 5htp and of course melatonin. And I also just started taking the nigella sativa. Magnesium biglycinate is new for me, it doesn't work at all for constipation but it does provide some glycine. GABA too. My sleep doctor said the gaba/glycine works essentially the same as melatonin so he didn't see the need to add either of them. I found a study from U of Toronto saying that gaba/glycine in combination are helpful. It didn't give dosages.

I think the last few years with the lockdowns have been incredibly stressful and not beneficial for the condition. My doctor also said the more sleep the better, and the more regular a sleep schedule the better.

[Bolt_Upright in reply to nuttywally]

10 years RBD and no PD, I don't know if I would change anything

So how is your RBD going? I hit a rough spell with episodes 5 out of 6 nights. I backed off some supplement changes and hopefully I will be back on track.

Niacin is one I have more confidence in.

I need to look into Spirulina, Phosaphatidyl Serine, and 5HTP.

And maybe it is time to give Melatonin another try. I think Melatonin is the only treatment that has been shown to prevent RBD from progressing to PD.

Thanks for sharing!