Protein simulation, experiments unveil cl... - Cure Parkinson's

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Protein simulation, experiments unveil clues on origins of Parkinson's disease

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A new study looks into how PD forms and develops by using Highly advanced techniques . " researchers from Penn State College of Medicine and The Hebrew University of Jerusalem have developed an integrative approach, combining experimental and computational methods, to understand how individual proteins may form harmful aggregates, or groupings, that are known to contribute to the development of the disease. They said their findings could guide the development of new therapeutics to delay or even halt the progression of neurodegenerative diseases. Using leading-edge experiments, the researchers found that some shapes of alpha-synuclein are surprisingly stable and last longer than milliseconds. They said this is much slower than estimates of a disordered protein that constantly changes conformations. " Study Excerpt

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