CD4 T cells, alpha-synuclein, microglia, neuroinflammation

[aspergerian]

CD4 T cells react to local increase of α-synuclein in a pathology-associated variant-dependent manner and modify brain microglia in absence of brain pathology.

2018.

ncbi.nlm.nih.gov/pmc/articl...

Microglia response during Parkinson's Disease: alpha-synuclein intervention.

2018.

ncbi.nlm.nih.gov/pmc/articl...

Dopamine Receptor D3 Expression Is Altered in CD4+ T-Cells From Parkinson's Disease Patients and Its Pharmacologic Inhibition Attenuates the Motor Impairment in a Mouse Model.

2019.

frontiersin.org/articles/10...

Neuroinflammation: Microglia and T Cells Get Ready to Tango.

[aspergerian]

Neuroinflammation: Microglia and T Cells Get Ready to Tango

ncbi.nlm.nih.gov/pmc/articl...