What the Heck is Butyrate and How Can It ... - Cure Parkinson's

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What the Heck is Butyrate and How Can It Save Your Brain and Improve Your Mood?

Kia17 profile image
45 Replies

Don’t wait for a butyrate-based drug “someday.” Today you can start to boost your brain health and mood (as well as your colon health) by boosting the butyrate circulating in your body.

medium.com/@poetpete/how-ca...

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Kia17 profile image
Kia17
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45 Replies

Kia,

Thank you for posting this because it is already established that PWPs are not only deficient in butyrate, but also deficient in many of the bacteria that can interact with prebiotics and fiber to produce butyrate. Butyrate is fairly high on that chain and produces other factors and effects that can also have a positive impact for PWPs such as hydrogen sulfide or histone deacetylase inhibition!

Many of the people who take mannitol are not aware that mannitol can act as a prebiotic to interact with the correct bacteria in the gut to produce butyrate. Now if they would just produce mannitol with butyrate producing bacteria for PWPs!

Art

Kia17 profile image
Kia17

The 19 Best Prebiotic Foods You Should Eat

healthline.com/nutrition/19...

Let us know how that works out for you, Kia !

Art

Kia17 profile image
Kia17

Art

I deleted my earlier reply by mistake.

If I try Chicory Root. I will update here.

Thanks

Kia

Astra7 profile image
Astra7

You can get your daily requirements in 2 teaspoons of butter a day.

The other day there was an article about garlic, so lucky for us an excuse to eat garlic bread daily. Some good news at last!!

munchybunch profile image
munchybunch in reply to Astra7

What was the article on garlic??

Astra7 profile image
Astra7 in reply to munchybunch

Someone posted something about garlic a few days ago - it’s good for us apparently!

Kia17 profile image
Kia17 in reply to Astra7

Garlic post

healthunlocked.com/parkinso...

JANVAN profile image
JANVAN in reply to Astra7

Butter is a diary product.....which kind of butter do you mean ??

kgold profile image
kgold in reply to JANVAN

Use ghee.

Astra7 profile image
Astra7 in reply to JANVAN

Any butter I guess. I’ll try and find the article I was reading that mentioned it.

Rhyothemis profile image
Rhyothemis in reply to JANVAN

I looked into this a while back and found it very hard to find scientific reports listing butyrate quantities in foods. I did come across a mention in a book titled 'The Epigenetics Revolution' of an Icelandic fermented butter that contained very high amounts of butyrate. Apparently, onset of a disease called hereditary cystatin C amyloid angiopathy is delayed in Icelanders who have the gene and consume a traditional diet that includes the fermented butter and dried fish compared to those who have adopted a modern diet. According to the internet, Icelandic fermented butter is 'disgusting'; butyrate is associated with rancidity. Other varieties of cultured / fermented butter might have more than regular butter, but how much more, idk. Fiore Sardo cheese is also supposed to have a lot of butyrate; Pecorino Romano is described as having a similar flavor/aroma.

Rhyothemis profile image
Rhyothemis in reply to Rhyothemis

update - I have since learned that tributyrin should work just as well as butyrate, and tributyrin is in unfermented butter. So organic butter should work okay.

JAS9 profile image
JAS9

Some (rather unpleasant) things to consider if you want to increase your butyrate: youtu.be/NUyi3UfzBYI

WinnieThePoo profile image
WinnieThePoo

Nice digestible coverage of the subject. I shall be sticking with my Mediterranean diet for now- generating plenty of butyrate from resistant starch, pectin and inulin, and promoting the relevant bacteria.

This is a slightly less digestible version - but singing from the same hymn sheet

sciencedirect.com/science/a...

Jandeb profile image
Jandeb

You can purchase butyrate supplements. I buy one from TessMed or Tesseract.

Millbrook profile image
Millbrook

Hi. My husband takes probiotics but recently I purchased Miyarisan tablets of clostridium butyricum from eBay. In Asia they are well versed with this form of probiotics. Waiting for them to arrive and will let you know how it goes

Millbrook profile image
Millbrook in reply to Millbrook

My husband has been on miyarisan probiotics since my last post. His stomach issues have resolved and since there are many benefits from consuming clostridium butyricum for the brain he will be continuing with it. You can buy it on amazon

Gioc profile image
Gioc in reply to Millbrook

I was wondering if they come alive from Japan, being bacilli. I used probiotic3 AOR plus xylitol and I found myself well.

amazon.de/Advanced-Orthomol...

Millbrook profile image
Millbrook in reply to Gioc

Hi Gio. I knew someone on this forum was using AOR but could not place the person. Thanks for letting me know. The Miyarisan Probiotics come in little tablets and the dose is 9 tablets 3x a day which give you 1 million clostridium butyricum. I emailed the company to get this information. It is formulated such that it does not need to be refrigerated and was discovered in 1933. In 1970 the Japanese ministry of health approved it for clinical use as quasi medicine. Two capsules of AOR gives 1.2 m clostridium butyricum and Enteroccus faecium T110 36 m. I have not worked out which is more cost effective and I have no knowledge of enteroccus faecium and what it does. The link below has an article on how clostridium butyricum (CB) is good for vascular dementia and neurological conditions

hindawi.com/journals/bmri/2...

The strong miyarisan tablets at dose of 9 small tablets contain 270 mg powder equivalent to 1 million CB.

The large bottle with 1000 tablets costs about usd 51.

Butyricum became more effective when consumed with fibre, pectin, apples or bananas.

Prior to this I was using California Gold Probiotics 100 billion that had the 5 most common bacillus

Millbrook profile image
Millbrook in reply to Millbrook

Thanks to the people in this forum I got to know about butyrate and clostridium butyricum. I then did some research and discovered miyarisan probiotics. The Japanese have always been ahead in probiotics and ubiquinol

Gio, you may be interested in this article

pentec-consulting.eu/entero...

Gioc profile image
Gioc in reply to Millbrook

Thank you very much Millbrook, very interesting. Keep me updated on this subject.

PS. Take a look at xylitol is a great prebiotic for the genus prevotellaceae.

healthunlocked.com/parkinso...

Gio

Millbrook profile image
Millbrook in reply to Gioc

Thanks Gio. My husband is currently taking 1 tsp of syncolein- non gassy mannitol-that’s all he can manage as it still gives him gas and discomfort . I am still trying to settle his list of supplements which get longer and longer. After 3 months on the miyarisan tablets his stomach issues of bloatedness, indigestion and reflux (he used to have to take nexium and omeprazole) have been resolved. CD has also been known to help with the helicobacter where antibiotics have failed. So it is a promising probiotic

Gioc profile image
Gioc in reply to Millbrook

Millbrook,

I am happy for your husband. I have the same problem of reflux for jatale hernia and this probiotic ( clostridium butyricum ) helped me a lot, Keep in mind that I am one without rules on food, and my wife goes crazy to put me on a diet.

I give a try at the brand you suggest, thank you. :-)

Despe profile image
Despe in reply to Gioc

Gio, my friend,

Are you still taking this? amazon.co.uk/Advanced-Ortho...

Gioc profile image
Gioc in reply to Despe

Hello Despe, no now not anymore. It was good but I switched to the miyarisan because it's even better.IMHO These two are the only two I can say that make a difference to my gut. I don't know why but they work well and right away.

Despe profile image
Despe in reply to Gioc

Thank you, Gio. :) Although I ordered miyarisan, I wanted to have your opinion, too, as you have Hernia, too, like my husband. Did you have it operated on?

Gioc profile image
Gioc in reply to Despe

So far I have managed to contain esophageal inflammation with periods and avoiding very fatty foods and alcohol, antacids and Miyarasan to promote emptying. If I get to have swallowing problems or pain I would consider the surgery. Now I don't feel the need. The only problem is that I can't sleep on my right side, which I prefer. I don’t like surgery☹️

Despe profile image
Despe in reply to Gioc

I hear you. Husband had three major surgeries and he doesn't want to have another one, too (Hernia). Early this week, he had a severe episode with pain, fever, and shaking so bad (his whole body was shaking like a fish out of the water) that got us both very worried. We went to our family doctor, but he didn't know why the severe shaking. Fever (for one day) could be from accumulating waste in his intestines, doctor said. He is over this now, thank God.

Gioc profile image
Gioc in reply to Despe

Hi Despe,

I understand ... Episode of intense tremor also happened to me in conjunction with fever and stress, but the answer for me is always diet, fasting, rest and magnesium carbonate which hydrates the intestine, b1. the excessive tremor passes within the day. If you know it works, it helps take away the anxiety. A caragiver who express a confidence helps Pwp, ... easy to say but not to do, I know. It takes competence and the ability to confront problems while keeping calm and we are not doctors. The PD always presents new situations as you well know, but it increases our ability to face and solve problems. There is like a line that divides the attitude of life, on the one hand the problem is posed and on the other it is resolved. The PD forces us to be on the side of the solver and a little on the side of the problem. IMO this part is more causative, staying on the solver's side will make a difference, so let's keep this point of view. This also applies to PWPS.

Despe profile image
Despe in reply to Gioc

Gio,

You wrote like a champion who has taken the bull (PD) by the horns! I wish my husband had your attitude. . . I am there to fight for him and comfort him like the other day when he had this unexpected episode of extreme pain right above his hernia and intense shaking. I just hugged him as hard as my little body could and calmed him down. I was scared to death to, but I tried hard not to show it. We, care partners/spouses, have shortcomings, too, but we try to overcome them for our loved one's sake, and that, my friend, is not easy, physically and emotionally.

Gioc profile image
Gioc in reply to Despe

You are the champion !!!

An example of great love and sense of duty, high motivations, which are more indispensable than care. Thank you so much Despe for a good example.

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P.S. If it can help you: everyone is kindly invited to move from "I the problem" to "I the solution" also a pwp, it is a matter of point of view. :-)

Despe profile image
Despe in reply to Gioc

You're right, but it's easier said than done. :)

Despe profile image
Despe in reply to Millbrook

Hello Mill!

Is your husband still on Clostridium butyricum? How is he doing? Mine was diagnosed with Hernia and he had a severe episode of pain and constipation. It has resolved, but I was wondering is this butyric acid will help him.

Thank you!

Millbrook profile image
Millbrook in reply to Despe

Hi Despe,

My husband had hernia 3 years ago and had surgery to fix it.

He is still taking miyarisan probiotic made of clostridium butyricum because butyrate has the action of clearing alpha synuclein. It helped tremendously for bloating and gas and since taking it he has no need of omeprazole, nexium, motilium and the like- meds that he had been taking since 2004.

He did not take it specifically for hernia but if you check Gio’s post clostridium butyricum helped his hernia.

Hope that helps

Despe profile image
Despe in reply to Millbrook

Thanks, Mill, and sorry for my delayed response. A couple of days ago, he had this attack with lots of pain and his whole body shook like a fish out of the water. We both got scared. Our Internist couldn't explain it. He took X-rays and diagnosed a lot of waste was not eliminated. That was the first time he experienced such an episode. Guess Hernia will cause severe pain at times. We have seen a surgeon, but husband is really reluctant to have the surgery, especially if they use mesh.

I have checked on Amazon for Butyric Acid supplements. Still investigating. . .does Miyarisan probiotic have a strong odor?

Millbrook profile image
Millbrook in reply to Despe

No, Miyarisan has no odor at all. My husband had the mesh keyhole surgery so recovery was much faster

Despe profile image
Despe in reply to Millbrook

Mill,

Thank you! I will order same, Miyarisan. I appreciate your insight, helped me decide what to order. I hope there will be some English instructions. How many does your husband take a day?

Millbrook profile image
Millbrook in reply to Despe

Hi Despe,

At the back of the bottle it says 3 little pills 3x a day so that wd be 9.

I read an article specifically on this product that said you could take up to 18 a day divided into 3 doses.

My husband takes 4 tablets 3 x a day as a maintenance dose

Despe profile image
Despe in reply to Millbrook

Thank you. We will give it a try. He will probably complain for taking more "pills." :)

Despe profile image
Despe in reply to Millbrook

I am sorry for bombarding you with my questions, one last: Is your husband taking any other probiotics? Mine is taking Bio-Kult, does he need to stop those and take just Miyarisan?

Thanks a million!

Millbrook profile image
Millbrook in reply to Despe

He only takes Miyarisan and no other probiotic . I understand as my husband also takes many pills. He also takes the coffee cherry by swansons . Getz introduced me to it as it is supposed to increase BDNF by 141%.

Despe profile image
Despe in reply to Millbrook

Oh no! Another supplement to the list for my husband? He will hate me. :)

Yes, I remember reading about coffee cherry benefits. I have to refresh my memory on that one before I order it. Never ending battle, Mill. :(

Thank you!

akgirlsrock profile image
akgirlsrock

I'm going to try bravo yogurt, research is very interesting. It's $$, but a lot of people have been helped, YouTube bravo.

Rhyothemis profile image
Rhyothemis in reply to akgirlsrock

A lot of $$. I looked into Bravo after David Sinclair mentioned it in an interview. $400 for a three month supply of yogurt starter culture:

bravo-probiotic-yogurt.com/...

Maybe it's worth it {shrug} ...

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