A well balanced, advanced article about prognostic indictor use and overuse in CLL with a discussion on MRD, minimal residual disease, and what it means...and a warning...
Handle with Care!
'MRD status should not be used to guide therapy outside of clinical studies because it is still the subject of ongoing research.'
Going from MRD Negative to MRD Positive in 3 Months 
Update- My Imbruvica plus Venetoclax Captivate trial. 
MRD Negative with significantly enlarged lymph nodes
Unmutated CLL and MRD-
Side Effects of Long Term use of acyclovir when on Ibrutinib+venetoclax 
