Hi All, some time ago I read a very interesting article, (It may even have been on this Website.)
It was regarding a Trail done many years ago, in one of the Scandanavian Countries, I think.
Three men with CLL had their T Cell taken out and either re-booted, or fake ones replacing them.
When re tested, none had CLL,, and 10 years after the event, one of the CLL'rs was very healthy, and doing extreme sports whilst still in remission.
I think they all had been tod that they were cured. (I know unlikely) but that was what they had been told. said.
I put this to my Haemo man, and he confirmed this information in total, but seemed to dismiss the value of the trial, and told me that it was never followed up. He did not say why, and I did not push the point, as I felt, he wanted to move on.
My question to you all is this:, Is there is any substance to this, that you know off.
Any info, gratefully received. Regards All, Ron
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"that it was never followed up" is entirely incorrect. The development of various CAR-T and now CAR-NK treatments for a range of cancers has continued over the past 11 years. CLL specific CAR-T trials are running currently in the USA, the UK and Australia that I know of.
Rob, one of our UK members and a past volunteer, is providing us with regular updates of his CAR-T trial progress: healthunlocked.com/cllsuppo...
Wow Neil it's been 4 years for Brian? Unbelievable how fast that went. I hope it proves to be the cure in the future. I know it's risky (not for everyone) but I hear they trying to treat better. Am I right?
To the best of my knowledge ALLCAR19, the trial I am on is the only way to get CAR-T therapy in UK if you have CLL. It is a Stage 1 trial, testing for safetly. CAR-T has been used more with other blood cancers. There were 50 places on ALLCAR19, 10 for CLL patients.
However, my information is from when I was researching it in Dec/Jan so there may have been changes.
My hope for the future is that something comes from the current CAR-T therapies that is easier on the patient, less risky, less time consuming and therefore less costly. I read something yesterday about some work that had been done (not in humans) that could put CAR-T cells back that were deactivated and could be activated/deactivated by a drug. If this comes to trial in the future it could be another great step forwards.
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