An unreviewed paper says that the efficacy of a 2nd Covid jab on cancer patients is as good as the general pop'n. Anybody know more?

[Quercus_robur]

theguardian.com/world/2021/...

Paragraph 12 says: "Antibody levels after one jab are also lower in people with some underlying health conditions, including cancer, diabetes and heart disease, and also those taking immune system suppressing medication, usually for cancer. However, again that difference disappeared once all participants had their second vaccine, the researchers said."

[cajunjeff]

I think this is great news, however, it appears to not distinguish among different types of cancers. Cll is a cancer specifically of lymphocytes, the white blood cells that create antibodies. Cll is therefore a more immune suppressive cancer than most others. Since Cll patients make up only a small fraction of cancer patients, this data might not apply to us.

I still think it is good news. The vaccines are working for a lot of people with Cll if you go only by antibody response. The vaccines might be helping our immune systems in ways that are not measured by antibody tests. And the more effective vaccines are for the general population, the better for us in terms of some degree of herd immunity.

There is very little data specific to vaccine efficacy and Cll cancer patients specifically. What little data there is so far is mixed, with those of us with Cll who have never treated having a good chance to produce antibodies and those of us in treatment with certain monoclonal antibodies and btk inhibitors not producing measurable antibodies at all for the most part. I don’t think this paper changes that.