Ibrutinib and Rivaroxaban

[Abc123qaz]

Hi, into my seventh week of Ibrutinib when I experienced chest pain on exertion also A-fib happening more frequently. Ended up in CCU in local hospital. Had an Angiogram and discovered mild coronary plague . Now on rivaroxaban but taken off Ibrutinib. Four days later lymph nodes swelling and sore. Have to wait 6 weeks before starting new drug for CLL. Has anyone else had this experience? Not feeling good, very fatigued!!

Eileen

[PlanetaryKim]

Sorry to hear about all you are going through Eileen. What new CLL drug will they be starting you on? Acalabrutinib by any chance?

I was taken off ibrutinib earlier this year and switched to Venetoclax because of Afib. This is a more common problem than was originally recognized with ibrutinib.

Good luck to you!

kim

[Abc123qaz in reply to PlanetaryKim]

Not sure what drug I’ll be on next Kim, It will be a long 6 weeks waiting for the Ibrutinib to leave my system and the lumps are back already!! I’ll let you know as soon as I know.

Thank you,

Eileen

[wmay13241]

Afib is a known Ibrutinib problem. My wife takes Toprol XL 50 mg for her Ibrutinib-caused afib - seems to control it.