Flu vaccine cuts infection severity and mortal... - CLL Support

CLL Support

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Flu vaccine cuts infection severity and mortality according to US Centers of Disease studies. That's why it is recommended if you have CLL.

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AussieNeilAdministrator
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Given reports of people getting the flu after their flu vaccinations (there's no live virus, so getting the flu from the vaccination is impossible), or claiming that the flu vaccination provides little to no benefit, it is good to see the reduction in illness and mortality following vaccination being quantified in recent research studies.

"After propensity-weighted adjustment to create better parity between the vaccinated and unvaccinated patients, the results showed that people 18-64 years old with vaccination had statistically significant decreases in mortality of a relative 36%, need for mechanical ventilation of 34%, pneumonia of 20%, and need for ICU admission of a relative 19%, as well as an 18% drop in average ICU length of stay, Shikha Garg, MD, said at the meeting. The propensity-weighted analysis of data from people at least 65 years old showed statistically significant relative reductions linked with vaccination: 46% reduction in the need for mechanical ventilation, 28% reduction in ICU admissions, and 9% reduction in hospitalized length of stay."

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Another study found that, "During recent U.S. flu seasons, children and adults who contracted influenza despite vaccination had significantly fewer severe infections and infection complications, compared with unimmunized people, according to two separate reports from CDC researchers presented at an annual scientific meeting on infectious diseases.

Combined data from both seasons showed that vaccinated children were 50% less likely to have been hospitalized for an acute influenza infection, compared with unvaccinated kids, a pattern consistently seen both in children aged 6 months to 8 years and in those aged 9-17 years. The pattern of vaccine effectiveness also held regardless of which flu strain caused the infections, reported Angela P. Campbell, MD, a CDC medical officer."

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Our Pinned Post - Vaccinations for flu, pneumonia and other things, provides details on recommended vaccinations if you have CLL.

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Neil

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Justasheet1 profile image
Justasheet1

Neil,

Is there any real data that getting a second shot later is better for our crowd?

Jeff

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AussieNeilAdministrator in reply to Justasheet1

The article reports a benefit in children for their first season, so I would hope that benefit is also likely in adults "The findings from a total of more than 7,500 children immunized during the 2014-2018 seasons showed a clear increment in vaccine protection among kids who received two doses during their first season vaccinated, especially in children who were 2 years old or younger. In that age group, administration of two doses produced vaccine effectiveness of 53% versus a 23% vaccine effectiveness after a single vaccine dose, reported Jessie Chung, a CDC epidemiologist".

Perhaps someone else can reference adult studies? There must be a basis for some specialists recommending an additional dose.

Neil

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