ibrufin after angioplasty : I had... - British Heart Fou...

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ibrufin after angioplasty

Anynomous profile image
13 Replies

I had angioplasty 6 months ago and I accidentally took 400mg (2 tablets) of ibrufin today . Do I need to worry?

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Anynomous
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13 Replies
Anynomous profile image
Anynomous

Thanks thatwasunexpected , I am kept at low risk by GP I assume and did not have any major symptoms so far.

JennyRx profile image
JennyRx

400mg as a single dose isn’t really an issue. But ongoingly may cause gastric bleeds if you’re on antiplatelets like aspirin, clopidogrel or ticagrelor. Also there’s some evidence that ibuprofen can diminish aspirin’s antiplatelet effect. It can also elevate blood pressure in some people. So I wouldn’t worry. And just remember to avoid for the future (pharmacist here)

in reply toJennyRx

I had a serious stomach bleed and was really ill as a consequence caused by taking ibuprofen over a few days, and was borderline requiring a blood transfusion. Consequently I have nothing to do with it. And recently a friend found he was allergic to taking it, his lips and face were swollen. Steer clear of it is my advice. If paracetamol works for you use that, or as I try and do avoid 'painkillers' all together unless absolutely necessary.

JennyRx profile image
JennyRx in reply to

Those responses do happen, but are generally rare. But frightening when they do happen. They are listed on the info leaflet. Most people don’t read that because most people don’t have that sort of reaction. But paracetamol has a much narrower window of safety than most people realise. It’s very easy to accidentally overdose. Nothing is totally safe.

Anynomous profile image
Anynomous in reply toJennyRx

yeah , thanks jennyrx

fishonabike profile image
fishonabike

in addition to Jenny Rx's advice, i will add that studies so far indicate that the risk is largely with ongoing use of NSAIDs - a single dose is not a problem (unless you are allergic to them and that is clearly not the case for you!)

Anynomous profile image
Anynomous in reply tofishonabike

thanks fishonabike

in reply tofishonabike

As I mentioned above I had stomach bleed as a result of taking ibuprofen. In my case 'ongoing use' was for a few days only all within the prescribed limits. Terrible stuff, stay well clear!

fishonabike profile image
fishonabike in reply to

sadly this is a known side effect of NSAIDs (and Aspirin), but it does not affect everyone that way - it is also the reason for the recommendation that it should be taken after a meal or with food and not on an empty stomach - there are also enteric coated versions avaliable for that reason - when prescribed by doctors they also prescribe a proton pump inhibitor like omeprazole

in reply tofishonabike

Which is why I insisted on enteric coated low dose aspirin, although what that is doing further down my digestive tract is anyone's guess 😆

JennyRx profile image
JennyRx in reply to

in the only issue is enteric coated aspirin has a much reduced antiplatelet effect. Although I take it because I don’t want to be on a PPI regularly as it can cause osteoporosis and I’m on cancer treatment that can cause the same. So it’s a balancing act.

fishonabike profile image
fishonabike in reply to

there are suggestions that by altering the acidity levels in the stomach the gut mcrobiome further down the line is affect, with variable consequences

Anynomous profile image
Anynomous

thanks aaq91

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