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New vaccine strategy harnesses 'foot soldier' T-cells to provide protection against influenza.

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A team of researchers led by Yoshihiro Kawaoka, professor of pathobiological sciences at the University of Wisconsin–Madison School of Veterinary Medicine, has developed technology that could improve the production of vaccines that protect people from influenza B.

That technology is an influenza B vaccine virus “backbone” that would allow producers to grow vaccine viruses at high yield in mammalian cell culture rather than in eggs. Using the backbone as a template to add vaccine-virus-specific components, it would offer protection against both lineages of influenza B that circulate in the human population.

news.wisc.edu/new-more-effe...

Cell Reports Medicine. The research paper:

cell.com/cell-reports-medic...

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