From June 2015 to October 2017 (30 months) I was on a daily combination of Perindopril 4mg, Bisoprolol 1.25mg and Warfarin 2mg to treat high blood pressure and AF. Last October 2017 my hands and legs suddenly swelled up and I found it very difficult to get up from a normal chair or to move around. I lost my sense of balance.
In January 2018, I finally identified the culprit as Bisoprolol (and if you look at the various forums you can see the extent of the Bisoprolol problem). With the agreement of my GP I have now been off Bisoprolol for a month (whilst continuing with the Perindopril and Warfarin) and I am 90% back to normal.
However my hands are still somewhat swollen and I cannot bend my fingers to make a proper fist with either hand. I seem to have stopped getting better. Any ideas?