is erleada good ?

[Raminagrobis]

scheduled to take Erleada soon

Does anyone have any advice or suggestion ?

Thank you

[Tall_Allen]

I personally know 1 patient who is doing great with it, and 1 patient who had an allergic reaction to it. All you can do is try and see, and maybe have some Claritin on hand in case of rash or immune reaction.

[samill]

I have been taking apalutamide (Erleada) since February 2023. I am doing well. No notable side effects apart from the TSH (Thyroid Stimulating Hormone) which has increased significantly (20.5) and which I am monitoring.

Good luck

[Apple-cake]

My husband was switched to apalutamide from enzalutamide earlier this year as the latter was causing severe fatigue. Since the change he has been a very different man. The cancer remains controlled and his quality of life has improved no end. He says he feels better than he has for two years. So, worth a try I'd say but be mindful that it might not have the same effect on you.

[dhccpa in reply to Apple-cake]

Has it worked as well on PSA? Is he metastatic to distant areas? Thanks

[Apple-cake in reply to dhccpa]

Yes. PSA is stable

[Apple-cake in reply to Apple-cake]

He has local mets in hip and pelvis

[Sailing-Todd]

My husband has been on Prostap and Erleada since his Gleason 10 / PSA 1120 diagnosis in April 2022.

He is at present still doing remarkably well. Some fatigue and muscle loss, with last PSA 0.23, (reduction each month so far since diagnosis). Other bloods stable and he is going about his daily life without too much disruption compared to pre-PCa.

He feels weirdly lucky as things were pretty dire 18 months ago. Good luck to you both.

[Condor77]

Started Erleada & Lupron Jan 1 this year. PSA not detectable after 6 months. Only SE that I have experienced is rashes and diarrhea. Take Immodium AD for the diarrhea which controls it completely. Use a moisturizing cream for the rashes. Other than that no problems.

[NorYug in reply to Condor77]

I’ve been taking it for four years. Psa went to undetectable in about six months and has stayed there. No side effects really….other than a few that are more likely attributable to natural aging. Yes, I’m a lucky guy.

[PC-22]

I was first prescribed abiraterone but that made my blood pressure go sky high and I just didn’t feel well when taking it.

So the Doctor switched me to Erleada and I seem to tolerate it much better. I have been taking high blood pressure medication for years prior to my diagnosis but now I am on a very low dose as my blood pressure was becoming too low at times. I don’t know if this is due to Erleada or not though. But the timing of the change in blood pressure seems to correlate.

[dhccpa in reply to PC-22]

Are you metastatic to distant areas? Thanks

[PC-22 in reply to dhccpa]

Unfortunately yes I am. In my bones from skull to my feet. But I think I only have it in one lymph node in the pelvic region and with standard of care treatment along with Lutetium 177 as I am on a clinical trial via Mayo called PSMAddition it appears that my cancer is currently under control, but the trial folk along with my insurance company will not approve a PET Scan so I really do not know. But my PSA is considered undetectable.

[dhccpa in reply to PC-22]

Thanks, I didn't know that Erleada was used in metastatic patients.

[tayninhtom]

I've had good success with it. My mets in lymphs had been treated with SBRT, but PC in Brain took up residence. After Craniotomy, SAS radiation did not halt brain mets. once on Erleada, the mets went away. Clear 2 years and still working. MO, RO, GP all happy. I think it's working for me, but had to monitor dose to avoid kidney distress. Once dose set, all smooth sailing.

Side effects are significant. You MUST ramp up exercise to maintain any quality of life. Listen to the guys here. Without extensive exercise, I'd be a dishrag in front of the TV waiting to die.

Another thing, marijuana was an occasional pleasure of mine. Erleada changed that. I now have one good scotch before dinner. Anything else is too much.

[Cancer2x in reply to tayninhtom]

Great report Tom! I’m with you on the nightly Scotch. Hey, you probably made it in and back out of the Michelin Rubber Plantation alive. You can do this!

[tayninhtom in reply to Cancer2x]

Thanks, hate those rubber plantations, US Government should have charged Michelin for harboring enemy there. BTW, is your logo a tunnel rat?

[Cancer2x in reply to tayninhtom]

Hehe…no, too big for that! More like a Secret Squirrel.

[SteveTheJ]

Erleada is fine; it's better than cancer! I have had no issues attributable to Erleada in >3 years. I think the Lupron is responsible for the noticeable side effects; namely, fatigue and brain fog. Go for it!

[Chadsdad]

I’m 45 mths on Eligard, Erleada and Prolia all started at the same time. Results have been fantastic as far as a 0 PSA and <10 T level. Loss of libido, little brain fog, energy level lower than when started. Exercise, attitude and trying to eat healthy works for me. I used to be able to run faster than a freight train and leap tall buildings. Now I have to purchase a ticket and ride the elevator. But I’m still alive , so there’s that.

[j-o-h-n in reply to Chadsdad]

To Chad's Dad,

BTW for your info......escalators have been free for years.........but don't forget to hold onto the handrail.....

It should be noted that they may not be free (electric ⚡ya know) in the near future and if the AC/DC police catch you without a ticket or a ticket stub..................... Oh! New Zealand.... looking betterer and betterer every day...........

Good Luck, Good Health and Good Humor.

j-o-h-n Sunday 09/24/2023 3:34 PM DST

[pacificvo]

I'm taking Erleada from Sept 2021 untill now less SE than Zoladex, psa 0.03. But not good if you get covid, you have stop erleada 14 days before taking paxlovid.

[Izzysdad]

Been on Erleada for almost 3 years. PSA is still undetectable. I didn’t notice any additional side effects from what I already have with Eligard. I walk most days and do an hour resistance workout twice a week. I strongly recommend that. All blood tests in normal range ( except testosterone of course ) and hemoglobin is technically in the anemia range but I don’t feel any effects from that. I’m 72.