TRT anyone?: I was Dx Gleason 8 (4+... - Advanced Prostate...

Advanced Prostate Cancer

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TRT anyone?

900312611 profile image
21 Replies

I was Dx Gleason 8 (4+4) 2015 at 70 years old; had IMRT (25 sessions) & seeds early 2016; shortly after PSA went to .44, but progressively increased to 1.95 by Jan 16 2018; then started dropping: Feb 26 was 1.3, Apr 2 was 1.18, then July 2 it dropped to 0.83. by

11/29/19 0.11 PSA

6/2/20 0.06

8/31/20 0.06

3/2/21 0.03

8/27/21 0.03

12/2/21 0.02

2/25/22 0.02

8/26/22 0.01

12/12/22 0.01

2/27/23 <0.01

Aug 2022 it’s been 0.01 and Feb 2023 it was less than 0.01.;

My Testosterone has fallen also:

8/25/17 158.40 ng/dL

6/8/21 136 ng/dL

Oct 2022 87 ng/dL

The R/O never told me about daily Cialis or the pump, by the time I discovered them it was past atrophy, total ED; to date the ‘little’ fellow is just there…I’ve lost muscle, strength, and gained lower abdominal fat; I still workout (35 yrs) 4-5 days a week/weights; 5’10” tall and have gone from 210# (some muscle) to 195#, where triceps wave to you; strength now is nowhere was even a year ago. I read somewhere, don’t remember where, that TRT is ‘only’ for men who’ve had surgery and only if they’ve had low PSA for 2 plus years. Can I get opinions on TRT, how long you waited, if received after RT, SE, any regrets, age, etc…

Thank you

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21 Replies
mrscruffy profile image
mrscruffy

I regained muscle lost plus added muscle using SARMS, not sure what kind of effect or possible problems you may encounter using TRT

Geo99 profile image
Geo99 in reply tomrscruffy

mrscruffy. You're talking about sarms here and I'm very curious about that. I just purchased some osterine and was going to start on it in a couple of days.

Can you please share any experience you have with this ie, dosage, frequency Etc please? Because it's banned, it's very hard to get any information. Thanks!

mrscruffy profile image
mrscruffy in reply toGeo99

It is kind of a do it yourself experiment. I personally use 15mg a day, 20 mg was giving me fatigue. I workout lifting heavy 5 days a week and consume lots of protein. I cycle on and off, 6 weeks on and 4 weeks off. The only SE that I have encountered is a drop in my HDL which is a known SE, thus the cycling on and off. I gained an inch on my biceps in less than a year, have well developed shoulders and can leg press like crazy. When on cycle my lifts are about 10 lbs higher than off cycle. It was designed as a prostate cancer drug and suppresses T production. Zytiga was beginning to fail me and Ostarine gave me another year and a half of low PSA numbers. I have friends without Prostate Cancer who are using it and having fabulous results. You are correct it is a banned substance and I hear many athletes that test "dirty" is from using SARMS. Any other questions let me know, between my self and my trainer we can probably answer them. By the way it was introduced to me by my trainer as we weren't seeing results from my workouts, she is awesome. Good luck with it, I began to see subtle yet visible results into my second cycle. Take pics of yourself as a reference point and do body measurements.

Geo99 profile image
Geo99 in reply tomrscruffy

Thanks for the info!! I have always been muscular from years of lifting (I'm 67 as of today). I have never been really "big" at 5' 10" I usually would average about 165-168lbs. I started losing weight before my recent recurrance and dropped down to about 158. I am about to finish 28 days of Rad. and on Zytiga and Abi. for a month now. I see the mucle disappearing but still working on them albeit not as hard as I was. I'm hoping this Osterine will help me. It was great being on TRT for 9 years before the bad news popped up...again. I only have 1 pelvic node that "lit up" from the PSMA. No other Mets. Do you really think it's the Oster. that's helping you or the hard training and eating..? I think I will wait for my last 3 Rad. sessions and then start. Thanks again if you have any other insights....

mrscruffy profile image
mrscruffy in reply toGeo99

Pretty sure it is the Ostarine, I was working with my trainer and we just weren't seeing results until I started incorporating it

Geo99 profile image
Geo99 in reply tomrscruffy

That's really good to hear as is your Dr's. assessment.

Thanks!

mrscruffy profile image
mrscruffy in reply toGeo99

Also my MO new exactly what Osterine was and the science behind it. He couldn't recommend it but didn't have a problem with me taking it. When I asked him if I was his son would he recommend it he said,"yes"

Geo99 profile image
Geo99 in reply tomrscruffy

Sorry to bug you again but; How do you take the Ost? Mixed in water, a shake, right from the dropper/spoon? Thanks again.

mrscruffy profile image
mrscruffy in reply toGeo99

I take it in pill form. I asked my trainer and she said her clients using liquid put it under their tongue.

Geo99 profile image
Geo99 in reply tomrscruffy

I took about 10mg today under the tongue. OMG that tastes horrible.... lol. I will definately mix it in with something tomorrow. Thanks a lot mrscruffy!

mrscruffy profile image
mrscruffy in reply toGeo99

Don't forget to up your protein content. I do 1.2g per Kg as well as consume Creatine and BCCA's

fast_eddie profile image
fast_eddie in reply tomrscruffy

I wonder if DHEA could provide a similar benefit? Anyone use this?

webmd.com/diet/dhea-supplem...

I had to look up SARMS:

en.wikipedia.org/wiki/Selec...

mensjournal.com/health-fitn...

mrscruffy profile image
mrscruffy in reply tofast_eddie

The article says increases T. Might be risky

Tall_Allen profile image
Tall_Allen

I waited 3 years.

garyjp9 profile image
garyjp9 in reply toTall_Allen

3 years before starting TRT?

Tall_Allen profile image
Tall_Allen in reply togaryjp9

Yes. My PSA took that long to settle down convincingly after SBRT, so that I knew I wasn't recurrent.

garyjp9 profile image
garyjp9 in reply toTall_Allen

Thank you

London441 profile image
London441

Are you on ADT drugs, or were you?

900312611 profile image
900312611 in reply toLondon441

No ADT or anything like that; just radiation, and seeds and that was it...

London441 profile image
London441

I have no experience with TRT, but I did take HCG to assist in return of T post ADT treatment.

At age 78 and PSA 0.06 or lower for 3 years I would definitely try TRT if I were you. However, of equal importance is to increase the intensity of your weight training if you can do it safely. This would augment any exogenous T nicely.

j-o-h-n profile image
j-o-h-n

To all those who have lost muscle mass, don't fret cause of of that mass turns into politicians.....

Good Luck, Good Health and Good Humor.

j-o-h-n Thursday 07/06/2023 6:34 PM DST

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