ADT sensitizes prostate cancer cells to T-cell killing through androgen receptor dependent modulation of the apoptotic pathway

[MrG68]

Hi all,

For those of you taking enzalutamide and/or abiraterone as part of your treatments, here's an article I came across that describes what they do.It states that conventional therapies such as chemotherapy or radiation can be used in conjunction with these to leverage the effects and create a more potent treatment.

doi.org/10.18632%2Foncotarg...

Hope it helps.

[Scout4answers]

Cure is coming...

[andrew61 in reply to Scout4answers]

Very soon I hope.

[monte1111 in reply to Scout4answers]

I love cured ham.

[Seasid]

could you please fill out your profile information?

[Tony666]

very interesting. Thanks for sharing. It seems the previous view that ADT plus newer drugs only weakens cancer cells and allows radiation to kill them is wrong. The ADT and newer drugs can kill cancer cells even without radiation.

[monte1111]

Thanks for the post. As usual, I didn't understand a word of it.

[MrG68 in reply to monte1111]

Yep I can see why people find these things difficult/confusing. You're not alone. People generally read the abstract and conclusions without reading the main piece.

Maybe this could be more useful:

healthunlocked.com/advanced...

This ones relatively straight forward.

[Bjry]

I'm sure there are many others, but the only trial I could find is NCT01867333 - Enzaltamide with Prostvac. Started in 2013 and final results in January 2023. I can't any interim results so the only good news is that it hasn't been cancelled for futility.