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Advanced Prostate Cancer

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Specific Alcoholic Beverages & Prostate Cancer Status

pjoshea13 profile image
20 Replies

Interesting international study below [1].

"Intake frequency patterns of total alcohol were similar for non-PCa men and PCa patients after adjusting for demographic and other factors.

"However, PCa patients were more likely to drink wine (light/moderate, OR = 1.11 ...) and spirits (light/moderate, OR = 1.14 ... and heavy, OR = 1.34 ...) than non-PCa men.

"Patients with aggressive PCa drank more beer than patients with non-aggressive PCa (heavy, OR = 1.48 ...).

"Interestingly, heavy wine intake was inversely associated with PCa aggressiveness (OR = 0.56 ...)." {That's the choice I made years ago.}

-Patrick

[1] pubmed.ncbi.nlm.nih.gov/354...

Cancers (Basel)

. 2022 Apr 14;14(8):1981. doi: 10.3390/cancers14081981.

Intake Patterns of Specific Alcoholic Beverages by Prostate Cancer Status

Hui-Yi Lin 1 , Tung-Sung Tseng 2 , Xinnan Wang 1 , Zhide Fang 1 , Arnold H Zea 3 4 , Liang Wang 5 , Julio Pow-Sang 6 , Catherine M Tangen 7 , Phyllis J Goodman 7 , Alicja Wolk 8 , Niclas Håkansson 9 , Manolis Kogevinas 10 11 12 13 , Javier Llorca 13 14 , Hermann Brenner 15 16 17 , Ben Schöttker 15 , Jose Esteban Castelao 18 , Manuela Gago-Dominguez 19 20 , Marija Gamulin 21 22 , Davor Lessel 23 , Frank Claessens 24 , Steven Joniau 25 , The Practical Consortium 26 , Jong Y Park 27

Affiliations collapse

Affiliations

1 Biostatistics Program, School of Public Health, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.

2 Behavioral and Community Health Sciences Program, School of Public Health, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.

3 Department of Microbiology, School of Medicine, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.

4 Stanley S. Scott Cancer Center, Louisiana State University Health Sciences Center, New Orleans, LA 70112, USA.

5 Department of Tumor Biology, Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA.

6 Department of Genitourinary Oncology, Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA.

7 SWOG Statistical Center, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

8 Department of Surgical Sciences, Uppsala University, SE-751 85 Uppsala, Sweden.

9 Unit of Cardiovascular and Nutritional Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, SE-171 77 Stockholm, Sweden.

10 Barcelona Institute of Global Health (ISGlobal), 08036 Barcelona, Spain.

11 IMIM (Hospital del Mar Medical Research Institute), 08003 Barcelona, Spain.

12 Universitat Pompeu Fabra (UPF), 08002 Barcelona, Spain.

13 CIBER Epidemiología y Salud Pública (CIBERESP), 28029 Madrid, Spain.

14 University of Cantabria, 39005 Santander, Spain.

15 Division of Clinical Epidemiology and Aging Research, German Cancer Research Center (DKFZ), D-69120 Heidelberg, Germany.

16 German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), D-69120 Heidelberg, Germany.

17 Division of Preventive Oncology, German Cancer Research Center (DKFZ) and National Center for Tumor Diseases (NCT), Im Neuenheimer Feld 460, D-69120 Heidelberg, Germany.

18 Genetic Oncology Unit, CHUVI Hospital, Complexo Hospitalario Universitario de Vigo, Instituto de Investigación Biomédica Galicia Sur (IISGS), 36204 Vigo, Spain.

19 Genomic Medicine Group, Galician Foundation of Genomic Medicine, Instituto de Investigacion Sanitaria de Santiago de Compostela (IDIS), Complejo Hospitalario Universitariode Santiago, Servicio Galego de Saúde, SERGAS, 15706 Santiago de Compostela, Spain.

20 Department of Family Medicine and Public Health, Moores Cancer Center, University of California San Diego, La Jolla, CA 92037, USA.

21 Department of Oncology, University Hospital Centre Zagreb, 10 000 Zagreb, Croatia.

22 School of Medicine, University of Zagreb, 10 000 Zagreb, Croatia.

23 Institute of Human Genetics, University Medical Center Hamburg-Eppendorf, D-20246 Hamburg, Germany.

24 Molecular Endocrinology Laboratory, Department of Cellular and Molecular Medicine, Campus Gasthuisberg, University of Leuven, Herestraat 49, P.O. Box 901, 3000 Leuven, Belgium.

25 Department of Urology, University Hospitals Leuven, Herestraat 49, P.O. Box 7003 41, 3000 Leuven, Belgium.

26 The Prostate Cancer Association Group to Investigate Cancer Associated Alterations in the Genome Consortium, Sutton SM2 5NG, UK.

27 Department of Cancer Epidemiology, Moffitt Cancer Center & Research Institute, Tampa, FL 33612, USA.

PMID: 35454886 DOI: 10.3390/cancers14081981

Abstract

Background: Previous studies have shown that different alcoholic beverage types impact prostate cancer (PCa) clinical outcomes differently. However, intake patterns of specific alcoholic beverages for PCa status are understudied. The study's objective is to evaluate intake patterns of total alcohol and the three types of beverage (beer, wine, and spirits) by the PCa risk and aggressiveness status.

Method: This is a cross-sectional study using 10,029 men (4676 non-PCa men and 5353 PCa patients) with European ancestry from the PCa consortium. Associations between PCa status and alcohol intake patterns (infrequent, light/moderate, and heavy) were tested using multinomial logistic regressions.

Results: Intake frequency patterns of total alcohol were similar for non-PCa men and PCa patients after adjusting for demographic and other factors. However, PCa patients were more likely to drink wine (light/moderate, OR = 1.11, p = 0.018) and spirits (light/moderate, OR = 1.14, p = 0.003; and heavy, OR = 1.34, p = 0.04) than non-PCa men. Patients with aggressive PCa drank more beer than patients with non-aggressive PCa (heavy, OR = 1.48, p = 0.013). Interestingly, heavy wine intake was inversely associated with PCa aggressiveness (OR = 0.56, p = 0.009).

Conclusions: The intake patterns of some alcoholic beverage types differed by PCa status. Our findings can provide valuable information for developing custom alcohol interventions for PCa patients.

Keywords: aggressiveness; alcohol; beverage; prostate cancer.

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20 Replies
Garp41 profile image
Garp41

Beer (Hops) activaies ER-Alpha.Doug

Garp41 profile image
Garp41 in reply to Garp41

ncbi.nlm.nih.gov/pmc/articl...

Search Red Wine in article

Doug

pjoshea13 profile image
pjoshea13 in reply to Garp41

Doug,

For those who didn't:

"Among men with prostate cancer, red wine was associated with a lower risk of progression to lethal disease."

-Patrick

6357axbz profile image
6357axbz

🍸🍸🍷 🍷 🍷🍷

Graham49 profile image
Graham49

Drink red wine with your salmon!

noahware profile image
noahware in reply to Graham49

Pinot noir, or Chianti, can be great with salmon!

MateoBeach profile image
MateoBeach

I’m with you on the choice of heavy wine intake. Cheers Patrick, raising a glass to you. Paul

leo2634 profile image
leo2634

Johnny Walker Black after the first three the PC doesn't bother me as much.

pjoshea13 profile image
pjoshea13 in reply to leo2634

Scotch is one of the essential food categories. I like White Horse - & not just for the Lagavulin content. For malt, I would go with Talisker more often than not. Cheers!

leo2634 profile image
leo2634 in reply to pjoshea13

I'll need to try them for medicinal purposes only 😆

cigafred profile image
cigafred

One of your better finds, thanks Patrick.

pjoshea13 profile image
pjoshea13 in reply to cigafred

I thought you might approve. -Patrick

CharlieBC profile image
CharlieBC

As one who only drinks when I'm alone or with somebody, this is interesting. Two substances that need to be considered are sugar and glyphosate (Roundup). Dry reds are great- higher antioxidant properties, low sugar. But the fields are often sprayed with Roundup for weed control. In addition, lifestyle is a factor- salmon with wine, vs pork on the smoker with suds.

Oldie68 profile image
Oldie68

This study suggests that white wine consumption is associated with higher bone density

onlinelibrary.wiley.com/doi...

Perhaps something to think about if you are at risk of osteoporosis.

Gabby643 profile image
Gabby643

I don’t recommend “boozing” while fighting Cancer.

joeguy profile image
joeguy in reply to Gabby643

I dont recommend stopping everything you enjoy just because you have cancer....

GreenStreet profile image
GreenStreet

Cheers Patrick. Red wine is my alcohol of choice in moderation 🍷🙂👍

JPnSD profile image
JPnSD

Being of French origin....wine has been a life-long staple for me...and I enjoy it daily. However having a Gleason 9, stage 4, Decipher.78....seems to refute this study

pjoshea13 profile image
pjoshea13 in reply to JPnSD

Unfortunately, many in this group are probably exceptions to some beneficial association. The guys who benefited are in a different group.

j-o-h-n profile image
j-o-h-n

WATER................

Good Luck, Good Health and Good Humor.

j-o-h-n Tuesday 04/26/2022 6:01 PM DST

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